Antithrombotic Drugs in Thrombosis Models: 1st Edition (Hardback) book cover

Antithrombotic Drugs in Thrombosis Models

1st Edition

By Josef Hladovec

CRC Press

240 pages

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Hardback: 9780849351624
pub: 1989-08-31
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Description

Antithrombotic Drugs in Thrombosis Models presents a critical review of the use of thrombosis models and an original, highly sensitive methodology for testing antithrombotics based on a more adequate understanding of thrombotic processes. The methods form an integrated system stressing particularly the plurifactorial and global character of thrombosis and the key role of a generalized mild endothelial lesion. Packed with illustrations, this book documents the effectiveness of the system through the screening of a series of acknowledged and potential antithrombotics, and includes a unique study of their mutual combinations. Special emphasis is placed on the importance of biomodels for preliminary testing of antithrombotics. This book is particularly useful to researchers in pharmacology and the pharmaceutical industry; however, those interested in drug research and the field of cardiovascular medicine will benefit as well.

Table of Contents

Introduction. The Rational Basis of Thrombosis Models. Basic Methods. Effects of Antithrombotics and Results of Drug Screening. Drug Combinations. General Conclusions.

Subject Categories

BISAC Subject Codes/Headings:
MED038000
MEDICAL / Hematology
MED071000
MEDICAL / Pharmacology