Apoptosis in Neurobiology: 1st Edition (Hardback) book cover

Apoptosis in Neurobiology

1st Edition

Edited by Yusuf A. Hannun, Rose-Mary Boustany

CRC Press

296 pages

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Hardback: 9780849333521
pub: 1998-12-24

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The rapid growth of the study of apoptosis-mechanism-driven, regulated cell death-has created an urgent need for reliable documentation of the different approaches to and methods of studying the various aspects of the field. Apoptosis in Neurobiology is an important resource for researchers in this emerging frontier of biomedical study. This volume allows the uninitiated neuroscientist intellectual and practical access to the study of apoptosis, with special consideration to the nervous system. The first section concentrates on conceptual approaches to the study of apoptosis in neurobiology and its significance to the nervous system. The second section provides a user-friendly approach to methods and techniques in the study of apoptosis as applied to neurobiology.


… a nice introduction to the field of neuronal apoptosis and to methods for identifying apoptotic cells. … the editor and authors are to be commended for providing a coherent, although detailed overview, indicated by an average of over 170 references per chapter.

-Joseph A. Bobich, Chemistry, Texas Christian University, Fort Worth, Texas, USA

Table of Contents


Diseases and Concepts

Introduction: Occurrence, Mechanisms, and Role of Apoptosis in Neurobiology and in Neurologic Disorders, R.-M. Boustany and Y.A. Hannun

Cell Death in the Developing Nervous System, V. Narayanan

Neurodegenerative Disorders, D. Schmechel

Neurooncology and Cancer Therapy, N.F. Schor

Human Immunodeficiency Virus Type I, H.A. Gelbard

The Role of Proteases in Neuronal Apoptosis, S. Kaufmann

Molecular Mechanisms in the Activation of Apoptotic and Anti-Apoptotic Pathways by Ceramide, R. Dobrowsky


Assessment of Cell Viability and Histochemical Methods in Apoptosis, K. Puranam and R.-M. Boustany

Assessment of Ultrastructural Changes Associated with Apoptosis, D. Schmechel

Flow Cytometry in the Study of Apoptosis, M. Smyth

Methods Used to Study Protease Activation During Apoptosis, S. Kaufmann

Qualitative and Quantitative Methods for the Measurement of Ceramide, R. Dobrowsky

In Vivo Neuronal Targeting of Genes, A. Amalfitano

About the Series

Frontiers in Neuroscience

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Anatomy
SCIENCE / Life Sciences / Cytology
SCIENCE / Life Sciences / General
SCIENCE / Life Sciences / Neuroscience