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Application of Solution Protein Chemistry to Biotechnology




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ISBN 9781420073416
Published May 12, 2009 by CRC Press
456 Pages - 156 B/W Illustrations

 
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Book Description

Reflecting the versatility of the author’s science and the depth of his experience, Application of Solution Protein Chemistry to Biotechnology explores key contributions that protein scientists can make in the development of products that are both important and commercially viable, and provides them with tools and information required for successful participation.

One of the of the world’s most respected protein researchers, Roger Lundblad does not succumb to the notion that new is always better. The application of protein science to the practice of commercial biotechnology is traced to the underlying basic solution protein chemistry.  It is only by achieving this understanding that the full potential of protein science may be obtained in the development and characterization of the diverse products of modern biotechnology.  

Dr. Lundblad also goes far beyond the biopharmaceutical applications that are often equated with protein science today to demonstrate the field’s unique versatility. From the making of bread and the invention of adhesives to the production of pharmaceuticals and the development of recombinant DNA products— in each of these products, the role of the protein chemist remains prominent. The important point is that classical protein chemistry is a critical part of the practice of biotechnology in the marketplace.

Providing the direction and the foundational work needed by students as well as the details and hundreds of references needed by designers and developers, this remarkable work—

  • Delves into the application of protein science for producing products as diverse as adhesives, drug delivery systems, and quality food products
  • Explores chemistry of attachment of proteins and peptides to solid surfaces with regard to applications both for the improvement of steel and titanium and in DNA and protein microarrays
  • Describes the development of bioconjugates used in antibodies
  • Offers essential advice on guidelines required for producing licensed biopharmaceutical products

While he does include a great deal of material not found in other sources, Dr. Lundblad makes a point to separate what is truly new from that which has merely been renamed. A reference unlike most, scientists and students eager to learn will find a text that is as practical as it is purposeful.

Table of Contents

Introduction to the Solution Chemistry of Proteins

Application of Solution Protein Chemistry to the Study of

Biopharmaceutical Conformation

Chemistry of the Attachment of Proteins and Peptides to

Solid Surfaces

Protein Conjugates

Protein Hydrogels

Adhesives, Glues, and Sealants

Protein Drug Delivery

Application of Solution Protein Chemistry to Proteomics

Use of Chemical Modification to Produce

Biopharmaceutical Products

Food and Agricultural Chemistry

Index

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Author(s)

Biography

One of the world’s most respected protein researchers, Dr. Lundblad has authored and edited several books for CRC Press including the Biochemistry and Molecular Biology Compendium.

Reviews

...it is a container of a lot of entries taking us on a veritable guided tour through a large number of chemical reactions concerning proteins for practical and diverse biotechnological fields.
Proteomics, 2011

… The book is a very valuable source for specialists interested in various aspects of proteins — from physicians to biochemists, molecular biologists, geneticists, and biotechnologists. There is no doubt that this book will be very useful for medical schools and universities students and their teachers.
—G. Y. Wiederschain, Doctor of Biological Sciences, writing in Biochemistry (Moscow), 2010, Vol. 75, No. 6.