Applied Epidemiologic Principles and Concepts : Clinicians' Guide to Study Design and Conduct book cover
2nd Edition

Applied Epidemiologic Principles and Concepts
Clinicians' Guide to Study Design and Conduct

ISBN 9781315369761
Published December 14, 2017 by CRC Press
344 Pages 77 B/W Illustrations

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Book Description

This book provides practical knowledge to clinicians and biomedical researchers using biological and biochemical specimen/samples in order to understand health and disease processes at cellular, clinical, and population levels. Concepts and techniques provided will help researchers design and conduct studies, then translate data from bench to clinics in attempt to improve the health of patients and populations. This book presents the extreme complexity of epidemiologic research in a concise manner that will address the issue of confounders, thus allowing for more valid inferences and yielding results that are more reliable and accurate.

Table of Contents

Part I

Chapter One Epidemiologic Research Conceptualization
Chapter Two Epidemiologic Proposal Development & Protocol

Chapter Three Epidemiologic Research Challenge:  Confounding, and Effect Measure Modifier
Chapter Four Epidemiologic Case Ascertainment: Disease Screening & Diagnosis
Part II Epidemiologic Methods & Concepts
Chapter Five Epidemiologic Methods and the Measures of Disease Occurrence and Association

Chapter Six Epidemiologic Study Designs : Overview

Chapter Seven Ecologic Studies: Design, Conduct & Interpretation

Chapter Eight  Case-Control Studies: Design, Conduct & Interpretation 

Chapter Nine  Cross-sectional Studies: Design, Conduct & Interpretation
Chapter Ten Cohort Studies: Design, Conduct & Interpretation

Chapter Eleven Clinical Trials (Experimental Designs)

Chapter Twelve Epidemiologic Causal Inference in Clinical  and Quantitative Evidence Synthesis

Part III Perspectives, Challenges and Future  of Epidemiology

Chapter Thirteen Perspectives and Challenges in Epidemiology

Chapter Fourteen Role of Epidemiology in Health and Healthcare Policy

Chapter Fifteen Consequentialist Epidemiology in Clinical  & Translational Research

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Professor Laurens Holmes Jr. was trained in internal medicine, specializing in immunology and infectious diseases prior to his expertise in epidemiology-with- biostatistics. He is an advocate of reality in modeling of epidemiologic, clinical and biomedical research data, consequential epidemiology, as well as explanatory ecologic model in understanding the complex etiologies of health and disease. Over the past two decades, Dr. Holmes had been working in cancer epidemiology, control & prevention with substantial publication on hormonally-related malignancies mainly prostate, thyroid, cervical, and testicular. Other areas where his focus had been during the last fifteen years include pediatric malignancy namely ALL, AML, lymphoma, brain and CNS. His involvement in chronic disease epidemiology, control and prevention includes signal amplification and stratification in risk modeling and health disparities in hypertension, and diabetes mellitus with large legacy (preexisting US National Health Statistics Center) data. Professor Holmes is a pioneer of health disparities epidemiology where he presents on disentangling race in epidemiologic studies by re-considering the biologic,bio-molecular, genetic, epigenetic determinants of disease incidence, prevalence, morbidity, prognosis, severity and mortality.