1st Edition

Aromatherapy Basic Mechanisms and Evidence Based Clinical Use

    480 Pages 71 B/W Illustrations
    by CRC Press

    Recent clinical studies have demonstrated an impact of aromatherapy on the control of symptoms associated with human diseases not fully controlled by conventional therapy. Aromatherapy: Basic Mechanisms and Evidence Based Clinical Use provides an up-to-date compilation of background scientific information that advocates the application of currently developed clinical studies on the effects of aromatherapy to the treatment of human diseases such as mild, stress-induced mood disorders, infectious diseases, and age-related disturbances.

    The book encompasses all aspects of successful clinical use of aromatherapy, including phytochemistry, technology, and clinical trials. It outlines a rational basis for clinical translation of aromatherapy for treating human diseases in need of safer therapies. It also describes evidence-based use of aromatherapy in controlling clinical manifestations of severe diseases for which conventional therapies often fail, such as managing agitation and aggression associated with Alzheimer�€�s disease and other neurodegenerative diseases.

    Containing a wealth of references and a thorough presentation of knowledge on essential oils and aromatherapy, this book is a valuable resource for students, researchers, clinicians, and policy makers in health care systems. It details the current clinical uses of aromatherapy while promoting further clinical development in areas where therapy is lacking.

    Historical Notes on Essential Oils and Aromatherapy with Special Reference to Bergamot Essential Oil
    Alfredo Focà and Maria Carla Liberto

    The Olfactory System: From Odorant Molecules to Perception
    Simone Pifferi and Anna Menini


    Taxonomy, Morphology, and Physiology of Aromatic Plants: A Botanical Perspective
    Salvatore Ragusa

    Phytochemical Components of Aromatic Plants and Factors Influencing Their Variability
    Giancarlo Statti

    Aromatic Plants: Molecular Biology/Biotechnology Approach
    Candida Vannini and Marcella Bracale

    Extraction, Sample Preparation, and Analytical Methods for Quality Issues of Essential Oils
    Paola Montoro, Milena Masullo, Sonia Piacente, and Cosimo Pizza

    Technological Aspects of Essential Oils
    Maria Chiara Cristiano, Donato Cosco, and Donatella Paolino


    Essential Oils Exploited in Cytotoxicity Studies for Translation into Safer and More Effective Cancer Therapeutics
    Rossella Russo, Maria Tiziana Corasaniti, Giacinto Bagetta, and Luigi Antonio Morrone

    Phototoxicity of Essential Oils
    Michele Navarra, Marco Miroddi, and Gioacchino Calapai

    Essential Oils: Fragrances and Antioxidants
    Rosalia Crupi and Salvatore Cuzzocrea


    Aromatherapy and Neurotransmission: Behavioral and Neurochemical Studies
    Luigi Antonio Morrone, Laura Rombolà, Diana Amantea, Maria Tiziana Corasaniti, and Giacinto Bagetta

    Rational Basis for Research and Development of Essential Oils in Pain Trials
    Laura Rombolà, Luigi Antonio Morrone, Chizuko Watanabe, Hirokazu Mizoguchi, Tsukasa Sakurada, Laura Berliocchi, Maria Tiziana Corasaniti, Giacinto Bagetta, and Shinobu Sakurada

    Pain Relief by Local Peripheral Injection of Beta-Caryophyllene through Cannabinoid 2 Receptor
    Soh Katsuyama, Takaaki Komatsu, Giacinto Bagetta, Shinobu Sakurada, and Tsukasa Sakurada

    Essential Oils, the Immune System, and Inflammation
    Franca Marino, Raffaella Bombelli, and Marco Cosentino

    Antimicrobial Effects of Bergamot Essential Oil: From Ancient Medicine to Modern Research
    Alfredo Focà and Maria Carla Liberto


    Aromatherapy for the Treatment of Neuropsychiatric Symptoms of Dementia
    Luca Cravello and Carlo Caltagirone

    Aromatherapy in Dementia and Dementia-Related Neuropsychiatric Disorders
    Sergio Fusco, Francesco Corica, and Andrea Corsonello

    Therapeutic Applications of Aromatherapy in Pediatrics
    Samaneh Khanpour Ardestani, Cecilia Bukutu, and Sunita Vohra

    Aromatic Plants and Essential Oils in the Treatment and Prevention of Infectious Diseases
    Neda Mimica-Dukic, Natasa Simin, Ivana Beara, Dejan Orcic, Marija Lesjak, Marina Franciškovic, and Emilija Svircev


    Regulatory Issues in Aromatherapy
    Gioacchino Calapai

    Pharmacovigilance and Phytovigilance for a Safe Use of Essential Oils
    Alfredo Vannacci, Alessandra Pugi, Eugenia Gallo, Fabio Firenzuoli, and Alessandro Mugelli

    Essential Oils and Aromatherapy: Epidemiology of Their Utilization
    Anna Loraschi and Marco Cosentino


    Giacinto Bagetta, University of Calabria, Rende, Italy

    Marco Cosentino, University of Insubria, Varese, Italy

    Tsukasa Sakurada, Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan