1st Edition

Basic Mechanisms and Evidence Based Clinical Use

ISBN 9781482246636
Published November 24, 2015 by CRC Press
479 Pages 71 B/W Illustrations

USD $220.00

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Book Description

Recent clinical studies have demonstrated an impact of aromatherapy on the control of symptoms associated with human diseases not fully controlled by conventional therapy. Aromatherapy: Basic Mechanisms and Evidence Based Clinical Use provides an up-to-date compilation of background scientific information that advocates the application of currently developed clinical studies on the effects of aromatherapy to the treatment of human diseases such as mild, stress-induced mood disorders, infectious diseases, and age-related disturbances.

The book encompasses all aspects of successful clinical use of aromatherapy, including phytochemistry, technology, and clinical trials. It outlines a rational basis for clinical translation of aromatherapy for treating human diseases in need of safer therapies. It also describes evidence-based use of aromatherapy in controlling clinical manifestations of severe diseases for which conventional therapies often fail, such as managing agitation and aggression associated with Alzheimer’s disease and other neurodegenerative diseases.

Containing a wealth of references and a thorough presentation of knowledge on essential oils and aromatherapy, this book is a valuable resource for students, researchers, clinicians, and policy makers in health care systems. It details the current clinical uses of aromatherapy while promoting further clinical development in areas where therapy is lacking.

Table of Contents

Historical Notes on Essential Oils and Aromatherapy with Special Reference to Bergamot Essential Oil
Alfredo Focà and Maria Carla Liberto

The Olfactory System: From Odorant Molecules to Perception
Simone Pifferi and Anna Menini


Taxonomy, Morphology, and Physiology of Aromatic Plants: A Botanical Perspective
Salvatore Ragusa

Phytochemical Components of Aromatic Plants and Factors Influencing Their Variability
Giancarlo Statti

Aromatic Plants: Molecular Biology/Biotechnology Approach
Candida Vannini and Marcella Bracale

Extraction, Sample Preparation, and Analytical Methods for Quality Issues of Essential Oils
Paola Montoro, Milena Masullo, Sonia Piacente, and Cosimo Pizza

Technological Aspects of Essential Oils
Maria Chiara Cristiano, Donato Cosco, and Donatella Paolino


Essential Oils Exploited in Cytotoxicity Studies for Translation into Safer and More Effective Cancer Therapeutics
Rossella Russo, Maria Tiziana Corasaniti, Giacinto Bagetta, and Luigi Antonio Morrone

Phototoxicity of Essential Oils
Michele Navarra, Marco Miroddi, and Gioacchino Calapai

Essential Oils: Fragrances and Antioxidants
Rosalia Crupi and Salvatore Cuzzocrea


Aromatherapy and Neurotransmission: Behavioral and Neurochemical Studies
Luigi Antonio Morrone, Laura Rombolà, Diana Amantea, Maria Tiziana Corasaniti, and Giacinto Bagetta

Rational Basis for Research and Development of Essential Oils in Pain Trials
Laura Rombolà, Luigi Antonio Morrone, Chizuko Watanabe, Hirokazu Mizoguchi, Tsukasa Sakurada, Laura Berliocchi, Maria Tiziana Corasaniti, Giacinto Bagetta, and Shinobu Sakurada

Pain Relief by Local Peripheral Injection of Beta-Caryophyllene through Cannabinoid 2 Receptor
Soh Katsuyama, Takaaki Komatsu, Giacinto Bagetta, Shinobu Sakurada, and Tsukasa Sakurada

Essential Oils, the Immune System, and Inflammation
Franca Marino, Raffaella Bombelli, and Marco Cosentino

Antimicrobial Effects of Bergamot Essential Oil: From Ancient Medicine to Modern Research
Alfredo Focà and Maria Carla Liberto


Aromatherapy for the Treatment of Neuropsychiatric Symptoms of Dementia
Luca Cravello and Carlo Caltagirone

Aromatherapy in Dementia and Dementia-Related Neuropsychiatric Disorders
Sergio Fusco, Francesco Corica, and Andrea Corsonello

Therapeutic Applications of Aromatherapy in Pediatrics
Samaneh Khanpour Ardestani, Cecilia Bukutu, and Sunita Vohra

Aromatic Plants and Essential Oils in the Treatment and Prevention of Infectious Diseases
Neda Mimica-Dukić, Natasa Simin, Ivana Beara, Dejan Orčić, Marija Lesjak, Marina Francišković, and Emilija Svirčev


Regulatory Issues in Aromatherapy
Gioacchino Calapai

Pharmacovigilance and Phytovigilance for a Safe Use of Essential Oils
Alfredo Vannacci, Alessandra Pugi, Eugenia Gallo, Fabio Firenzuoli, and Alessandro Mugelli

Essential Oils and Aromatherapy: Epidemiology of Their Utilization
Anna Loraschi and Marco Cosentino

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Giacinto Bagetta, University of Calabria, Rende, Italy

Marco Cosentino, University of Insubria, Varese, Italy

Tsukasa Sakurada, Daiichi College of Pharmaceutical Sciences, Fukuoka, Japan