1st Edition

Aromatic C(sp2)−H Dehydrogenative Coupling Reactions Heterocycles Synthesis

By Bagher Eftekhari-Sis Copyright 2020
    324 Pages 100 B/W Illustrations
    by CRC Press

    324 Pages 100 B/W Illustrations
    by CRC Press

    This comprehensive text covers the research and development trends in the growing field of aromatic C–H dehydrogenative coupling reactions, leading to different types of heterocycles. The author provides answers to how these coupling reactions occur, what kinds of heterocycles are synthesized, and what their advantages are. The palladium-, rhodium-, iridium-, copper-, cobalt-, ruthenium-, and ferric-catalyzed aromatic C(sp2)–H dehydrogenative cross-coupling reactions are described in detail. A useful reference source for researchers and graduates in the field of heterocyclic chemistry and transition-metal-catalyzed dehydrogenative coupling reactions.





    Features:







    • Comprehensive volume on the synthesis of benzo-heterocycles via aromatic C(sp2)–H bond activation.






    • Heterocycles are of paramount importance to medicinal chemistry and drug discovery.






    • Provides a comprehensive literature survey on the construction of heterocycles.






    • Reaction procedures and mechanistic explanations are included, which will appeal to those in fine chemicals and pharmaceutical companies.


    Chapter 1: Five-Membered N-Heterocycles

    Chapter 2: Six- and Higher-Membered N-Heterocycles

    Chapter 3: N-Bridged Heterocycles

    Chapter 4: Five-Membered O-Heterocycles

    Chapter 5: Six- and Seven-Membered O-Heterocycles

    Chapter 6: N,O-Heterocycles

    Chapter 7: N,S-Heterocycles

    Chapter 8: S- and S,O-Heterocycles 

    Chapter 9: P-, and Si-Heterocycles

    Chapter 10: Natural Products Synthesis

     

    Biography

    Prof. Bagher Eftekhari-Sis obtained his PhD from Sharif University of Technology under the supervision of Prof. Mohammed M. Hashemi in 2009 and then joined the Chemistry Department of the University of Maragheh. His research field involves the synthesis of heterocyclic compounds, supported catalysts, and polymeric and nano-materials. He has some reviews in the fields of organic transformations, especially in the heterocycle synthesis trends in the leading chemistry journal Chemical Reviews.