Preface
About the Editors
List of Contributors
Chapter 1 What is an Astrocyte?: Diversity of Structures and Functions
Randy F. Stout, Jr. and David C. Spray
Chapter 2 Gap Junctions and Aquaporins
Eliana Scemes and Grazia Paola Nicchia
Chapter 3 Adhesion Molecules in Astrocytes
Nariko Arimura
Chapter 4 Multi-scale Astrocyte-Neuron Communication
Maria Amalia Di Castro and Andrea Volterra
Chapter 5 Blood-Brain Barrier and the Neural-Vascular Unit
Rolf Dermietzel and David C. Spray
Chapter 6 Oligodendrocytes: Gateway to the Panglial Syncytium
Irene Sargiannidou, Styliani Theophanous, and Kleopas A. Kleopa
Chapter 7 Critical Role of Astrocytes in the Development of Epilepsy
Christian Steinhäuser and Peter Bedner
Chapter 8 The Role of Glial Pathology in Autism Spectrum Disorders
S. Hossein Fatemi and Neelufaar Fatemi
Chapter 9 Astrocytes in Aging and Alzheimer’s Disease
Alexei Verkhratsky, Dmitry Lim, and Carlos Matute
Chapter 10 Astrocytes in Stroke
Madison L. Chandler, Mustafa Balkaya, and Alexander A. Mongin
Chapter 11 Astrocytes in Depression: Insights from Postmortem Human Studies and Animal Models
Christa Hercher and Naguib Mechawar
Index
Biography
Dr. Eliana Scemes is a professor at New York Medical College. She obtained her Ph.D. in general physiology from the University of Sao Paulo, Brazil, and obtained further postdoctoral training in neurobiology in Brazil and in neuroscience at Albert Einstein College of Medicine. Her research has made significant contributions to the understanding of astrocyte biology, focusing on gap junction proteins (connexins and pannexins) and their impact on CNS physiopathology. She has contributed over 100 publications, with an h-index of 49, in the form of research and review articles and book chapters, and has been a member of numerous professional societies and the editorial board member of many scientific journals.
Dr. David C. Spray is a professor in the Dominick P. Purpura Department of Neuroscience and Department of Medicine at Albert Einstein College of Medicine and an adjunct professor of biomedical engineering at the City College of New York. His Ph.D. in physiology at the University of Florida College of Medicine, supported by one of the first Centers for Neuroscience, dealt with transduction properties of peripheral sensory neurons. As a Grass Foundation Fellow and for more than a dozen years afterward, he spent summers doing research at the Marine Biological Laboratory in Woods Hole, MA. His primary research focus has been on gap junctions, where current research of the laboratory focuses on neuron–glial interactions in peripheral ganglia associated with several models of chronic pain and gap junction control of the blood–brain barrier at the astrocyte endfeet. Dr. Spray has published about 500 papers, with an h-index >100, and with Dr. Scemes, he has co-authored more than 50 original articles and reviews, primarily dealing with gap junctions and astrocytes. He has served on NIH study sections, including Molecular and Cellular Biology of Glia, which he chaired, and is on the editorial boards of numerous journals, including Glia.
