This volume provides a comprehensive overview of the rapidly developing field of asymmetric synthesis. Using easy to understand graphical abstracts it presents 348 important catalytic and stoichiometric reactions leading to the synthesis of optically active chiral compounds. The first part of the book covers reactions related to reductions, oxidations, carbon-carbon bond formation and carbon-heteroatom bond formation. Each graphical abstract is accompanied by a list of important keywords and references to assist the reader. The second part concentrates on experimental aspects, describing synthetic procedures for selected chiral reagents and chiral auxiliaries, and provides an invaluable reference tool for laboratory work. Written with both the graduate student and professional organic chemist in mind, this book will serve as an important resource for the synthetic organic chemist.
Table of Contents
1. Oxidation - Oxidative Addition to Carbon-Carbon Double Bond Carbon-Carbon Bond Formation - Conjugate Addition 2. Desymmetrization 3. Reduction - Carbon-Carbon Double Bond 4. Deprotonation and Protonation - Protonation 5. Carbon-Heteroatom Bond Formation - Carbon-Fluorine Bond Formation