This overview of autonomic pharmacology describes the anatomy, physiology and pharmacology of the autonomic involuntary nervous system. Covering the diverse group of drugs acting on the autonomous nervous system, their actions are reviewed together with their clinical uses, side effects, interactions and subcellular mechanisms of action. Information is organized in a logical flow, bringing together the latest advances in an integrated form on topics usually found only in a fragmented form.; This work is intended for all those researching in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry and molecular biology.
Section 1: Introduction. Anatomy and Physiology of the Autonomic Nervous System. Section 2: Sympathetic NORADRENERGIC Neurones. Sympathetic Neurotransmission. Drugs Affecting Noradrenergic Neurones. Sympathomimetic Amines. Alpha- and Bet-Adrenoceptor Antagonists. Section 3: Cholinergic Neurotransmission. Parasympathomimetic Amines. Muscarine Receptor Antagonists. Anticholinesterases. Drugs Affecting Autonomic Ganglia. Section 4: Non-Adrenergic Non-Cholinergic NANC Neurones. History and Evidence for NANC Neurones. Putative NANC Transmitters. Section 5: Subcellular Mechanisms of Autonomic Receptor Mediated Effects. Alpha-Adrenoceptors and Muscarine Receptors. Beta-Adrenoceptors. Section 6: Experimental Methodology. In Vivo Methods and Models. In Vitro Methods. Receptor Binding Methods.