Autonomous Positioning of Piezoactuated Mechanism for Biological Cell Puncture  book cover
1st Edition

Autonomous Positioning of Piezoactuated Mechanism for Biological Cell Puncture

  • Available for pre-order on May 3, 2023. Item will ship after May 24, 2023
ISBN 9781032277202
May 24, 2023 Forthcoming by CRC Press
208 Pages 104 B/W Illustrations

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Book Description

Autonomous Positioning of Piezoactuated Mechanism for Biological Cell Puncture gives a systematic and almost selfcontained description of the many facets of advanced design, optimization, modeling, system identification and advanced control techniques for positioning of cell puncture mechanism with piezoelectric actuator in micro/nanorobotics systems.

To achieve biomedical applications, reliability design, modeling, and precision control are vitally important for developing engineering systems. With the advances in mechanical design, dynamic modeling, system identification, and control techniques, exploiting them for the benefit of reliability design, precision control, and quick actuation of micro/nanomanipulation systems to expand the robot’s applications at the micro and nanoscales, especially for biomedical applications.

This book unifies existing and emerging techniques concerning advanced design, modeling and advanced control methodologies in micropuncture of biological cells using piezoelectric actuator with their practical biomedical applications.

The book is an essential resource for researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts.


• Provides a series of latest results in, including but not limited to, design, modeling, and control of micro/nanomanipulation systems utilizing piezoelectric actuator

• Gives recent advances of theory, technological aspects, and applications of advanced modeling, control, and actuation methodologies in cell engineering applications

• Presents simulation and experimental results to reflect the micro/nano manipulation practice, and also validate the performances of the developed design, analysis, and synthesis approaches

Table of Contents

1. Introduction.  2. Structural Design and Optimization of Cell Puncture Mechanism.  3. Dynamic Modeling, System Identification and Hysteresis Effect of the Cell Puncture Mechanism.  4. Position Tracking of Cell Puncture Mechanism using Composite Proportional Integral Sliding Mode Control with Feedforward Control.  5. Motion Control of Cell Puncture Mechanism based on Fractional Non-singular Terminal Sliding Mode.  6. Motion Tracking of Cell Puncture Mechanism using Improved Sliding Mode Control with Time Delay Estimation Technology.  7. Micro Force Tracking Control of Cell Puncture Mechanism based on Time Delay Estimation Technology.  8. Hybrid Control Strategy of Force and Position for Cell Puncture based on Adaptive Smooth Switching.  9. Automated Cell Biopsy Utilizing Micropuncture Technique


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Dr. Mingyang Xie, Nanjing University of Aeronautics and Astronautics, College of Automation Engineering.

Prof. Xie is one of the scholars in the field of micro/nano robot and micro/nano manipulation. He has published 1 academic books, 30+ academic papers, including 10+ papers in the top journals and conferences in the field of robotics, such as, IEEE/ASME Transactions on Mechatronics, IEEE Transactions on Automation Science and Engineering, IEEE Transactions on Control Systems Technology, IEEE Transactions on Biomedical Engineering, ICRA, IROS, AIM, etc..

Prof. Xie is currently the Associate Editor of the IET Electronics Letters, Designs, Guest Editor of the International Journal of Advanced Manufacturing Technology. He also serves as the workshop organizer of IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2019), invited session chair of IEEE International Conference on Advanced Intelligent Mechatronics (AIM 2019), PC member of IEEE International Conference on Robotics and Biomimetics (Robio 2019). He is currently served as reviewer of many top journals and conferences, such as, the IEEE Transactions on Robotics, the IEEE/ASME Transactions on Mechatronics, the IEEE Transactions on Industrial Electronics, the IEEE Transactions on Neural Networks and Learning Systems, the IEEE Transactions on Circuits and Systems-I: Regular Papers, International Journal of Robust and Nonlinear Control, ICRA, IROS, CDC, ACC, AIM. He is the Senior member of IEEE.

Dr. Shengdong Yu, Wenzhou Institute, University of Chinese Academy of Sciences.

Prof. Shengdong Yu obtained his M.S. and Ph.D. degree from Mechanical and Electrical College of Nanjing University of Aeronautics and Astronautics. He is currently an associate professor of Electromechanical Engineering with the Wenzhou Institute, University of Chinese Academy of Sciences (WIUCAC). His current research interests include micro/nanosystems, micro/nanomechatronics, smart materials and structures, and sliding mode control theory. He has published a series of academic papers on the research of micro/nano manipulation, such as, ISA Transactions, Journal of the Franklin Institute, Bio Design and Manufacturing, IEEE Transactions on Circuits and Systems I, etc..