1st Edition

Autonomous Positioning of Piezoactuated Mechanism for Biological Cell Puncture

By Mingyang Xie, Shengdong Yu Copyright 2023
    169 Pages 104 B/W Illustrations
    by CRC Press

    Autonomous Positioning of Piezoactuated Mechanism for Biological Cell Puncture gives a systematic and almost self-contained description of the many facets of advanced design, optimization, modeling, system identification, and advanced control techniques for positioning of the cell puncture mechanism with a piezoelectric actuator in micro/nanorobotics systems.

    To achieve biomedical applications, reliability design, modeling, and precision control are essential for developing engineering systems. With the advances in mechanical design, dynamic modeling, system identification, and control techniques, it is possible to expand the advancements in reliability design, precision control, and quick actuation of micro/nanomanipulation systems to the robot’s applications at the micro- and nanoscales, especially for biomedical applications.

    This book unifies existing and emerging techniques concerning advanced design, modeling, and advanced control methodologies in micropuncture of biological cells using piezoelectric actuators with their practical biomedical applications.

    The book is an essential resource for researchers within robotics, mechatronics, biomedical engineering, and automatic control society, including both academic and industrial parts.


    • Provides a series of latest results in, including but not limited to, design, modeling, and control of micro/nanomanipulation systems utilizing piezoelectric actuators

    • Gives recent advances of theory, technological aspects, and applications of advanced modeling, control, and actuation methodologies in cell engineering applications

    • Presents simulation and experimental results to reflect the micro/nano manipulation practice and validate the performances of the developed design, analysis, and synthesis approaches

    Ch 1. Introduction

    Ch 2. Structural Design and Optimization of Cell Puncture Mechanism

    Ch 3. Dynamic Modeling, System Identification and Hysteresis Effect of the Cell Puncture Mechanism

    Ch 4. Position Tracking of Cell Puncture Mechanism Using Composite Proportional Integral Sliding Mode Control with Feedforward Control

    Ch 5. Motion Control of Cell Puncture Mechanism Based on Fractional Non-singular Terminal Sliding Mode

    Ch 6. Motion Tracking of Cell Puncture Mechanism Using Improved Sliding Mode Control with Time Delay Estimation Technology

    Ch 7. Micro-Force Tracking Control of Cell Puncture Mechanism Based on Time-Delay Estimation Technology

    Ch 8. Hybrid Control Strategy of Force and Position for Cell Puncture Based on Adaptive Smooth Switching

    Ch 9. Automated Cell Biopsy Utilizing Micropuncture Technique



    Dr. Mingyang Xie, Nanjing University of Aeronautics and Astronautics, College of Automation Engineering.

    Prof. Xie is one of the scholars in the field of micro/nano robot and micro/nano manipulation. He has published 1 academic books, 30+ academic papers, including 10+ papers in the top journals and conferences in the field of robotics, such as, IEEE/ASME Transactions on Mechatronics, IEEE Transactions on Automation Science and Engineering, IEEE Transactions on Control Systems Technology, IEEE Transactions on Biomedical Engineering, ICRA, IROS, AIM, etc..

    Prof. Xie is currently the Associate Editor of the IET Electronics Letters, Designs, Guest Editor of the International Journal of Advanced Manufacturing Technology. He also serves as the workshop organizer of IEEE/RSJ International Conference on Intelligent Robots and Systems (IROS 2019), invited session chair of IEEE International Conference on Advanced Intelligent Mechatronics (AIM 2019), PC member of IEEE International Conference on Robotics and Biomimetics (Robio 2019). He is currently served as reviewer of many top journals and conferences, such as, the IEEE Transactions on Robotics, the IEEE/ASME Transactions on Mechatronics, the IEEE Transactions on Industrial Electronics, the IEEE Transactions on Neural Networks and Learning Systems, the IEEE Transactions on Circuits and Systems-I: Regular Papers, International Journal of Robust and Nonlinear Control, ICRA, IROS, CDC, ACC, AIM. He is the Senior member of IEEE.

    Dr. Shengdong Yu, Wenzhou Institute, University of Chinese Academy of Sciences.

    Prof. Shengdong Yu obtained his M.S. and Ph.D. degree from Mechanical and Electrical College of Nanjing University of Aeronautics and Astronautics. He is currently an associate professor of Electromechanical Engineering with the Wenzhou Institute, University of Chinese Academy of Sciences (WIUCAC). His current research interests include micro/nanosystems, micro/nanomechatronics, smart materials and structures, and sliding mode control theory. He has published a series of academic papers on the research of micro/nano manipulation, such as, ISA Transactions, Journal of the Franklin Institute, Bio Design and Manufacturing, IEEE Transactions on Circuits and Systems I, etc..