2nd Edition
Bacterial Resistance to Antimicrobials
444 Pages
by
CRC Press
444 Pages
by
CRC Press
448 Pages
by
CRC Press
Also available as eBook on:
The enormous genetic flexibility of bacteria jeopardizes the usefulness of currently available antibiotics, and requires new approaches to antibiotic discovery and development. Antimicrobial resistance can be acquired in a short time frame, both by genetic mutation and by direct transfer of resistance genes across genus and species boundaries. Understanding mechanisms of resistance is crucial... Read more
Microbial Drug Resistance: A Historical Perspective. Ecology of Antibiotic Resistance Genes. Global Response Systems that Confer Resistance. Multidrug Efflux Pumps: Structure, Efflux, and Inhibition. Mechanisms of Aminoglycoside Antibiotic Resistance. Resistance to ß-Lactam Antibiotics Mediated by ß-Lactamases. Target Modification as a Mechanism of Antimicrobial Resistance. Antibiotic Permeability. Genetic Methods for Detecting Bacterial Resistance Genes. The Evolution and Epidemiology of Antibiotic Resistant Pneumococci. Antimicrobial Resistance in the Enterococcus. Methicillin Resistance in Staphylococcus aureus. Mechanism of Drug Resistance in Mycobacterium tuberculosis. Antibiotic Resistance in Enterobacteria. Resistance as a Worldwide Problem. Public Health Responses to Antimicrobial Resistance in Outpatient and Inpatient Settings. Antibacterial Drug Discovery in the 21st Century.
Biography
Richard G. Wax, Kim Lewis, Abigail A. Salyers, Harry Taber
