Bio-MEMS: Technologies and Applications, 1st Edition (Hardback) book cover

Bio-MEMS

Technologies and Applications, 1st Edition

Edited by Wanjun Wang, Steven A. Soper

CRC Press

488 pages | 197 B/W Illus.

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pub: 2006-12-15
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Description

Microelectromechanical systems (MEMS) are evolving into highly integrated technologies for a variety of application areas. Add the biological dimension to the mix and a host of new problems and issues arise that require a broad understanding of aspects from basic, materials, and medical sciences in addition to engineering. Collecting the efforts of renowned leaders in each of these fields, BioMEMS: Technologies and Applications presents the first wide-reaching survey of the design and application of MEMS technologies for use in biological and medical areas.

This book considers both the unique characteristics of biological samples and the challenges of microscale engineering. Divided into three main sections, it first examines fabrication technologies using non-silicon processes, which use materials that are appropriate for medical/biological analyses. These include UV lithography, LIGA, nanoimprinting, injection molding, and hot-embossing. Attention then shifts to microfluidic components and sensing technologies for sample preparation, delivery, and analysis. The final section outlines various applications and systems at the leading edge of BioMEMS technology in a variety of areas such as genomics, drug delivery, and proteomics.

Laying a cross-disciplinary foundation for further development, BioMEMS: Technologies and Applications provides engineers with an understanding of the biological challenges and biological scientists with an understanding of the engineering challenges of this burgeoning technology.

Table of Contents

Introduction; Wanjun Wang and Steven A. Soper

BASIC BIO-MEMS FABRICATION TECHNOLOGIES

UV Lithography of Ultra-Thick SU-8 for Microfabrication of High-Aspect-Ratio Microstructures and Applications in Microfluidic and Optical Components; Ren Yang and Wanjun Wang

The LIGA Process: A Fabrication Process for High-Aspect-Ratio Microstructures in Polymers, Metals, and Ceramics; Jost Goettert

Nanoimprinting Technology for Biological Applications; Sunggook Park and Helmut Schift

Hot Embossing for Lab-on-a-Chip Applications; Ian Papautsky

MICROFLUIDIC DEVICES AND COMPONENTS FOR BIO-MEMS

Micropump Applications in Bio-MEMS; Jeffrey D. Zahn

Micromixers; D.E. Nikitopoulos and A. Maha

Microfabricated Devices for Sample Extraction, Concentrations, and Related Sample Processing Technologies; Gang Chen and Yuehe Lin

Bio-MEMS Devices in Cell Manipulation: Microflow Cytometry and Applications; Choongho Yu and Li Shi

BIO-MEMS APPLICATIONS AND SYSTEMS

Coupling Electrochemical Detection with Microchip Capillary Electrophoresis; Carlos D. García and Charles S. Henry

Culture-Based Biochip for Rapid Detection of Environmental Mycobacteria; Ian Papautsky and Daniel Oerther

MEMS for Drug Delivery; Kabseog Kim and Jeong-Bong (J-B.) Lee

Microchip Capillary Electrophoresis Systems for DNA Analysis; Ryan T. Kelly and Adam T. Woolle

Bio-MEMS Devices for Proteomics; Justin S. Mecomber, Wendy D. Dominick, Lianji Jin, and Patrick A. Limbach

Single-Cell and Single-Molecule Analyses Using Microfluidic Devices; Malgorzata. A. Witek, Mateusz L. Hupert, and Steven A. Soper

Pharmaceutical Analysis Using Bio-MEMS; Celeste Frankenfeld and Susan Lunte

Index

Subject Categories

BISAC Subject Codes/Headings:
SCI053000
SCIENCE / Optics
TEC008070
TECHNOLOGY & ENGINEERING / Electronics / Microelectronics
TEC021000
TECHNOLOGY & ENGINEERING / Material Science