1st Edition

Bioactive Peptides

Edited By John Howl, Sarah Jones Copyright 2009
    504 Pages
    by CRC Press

    504 Pages
    by CRC Press

    Focuses on Biology, Pharmacology, and Therapeutic Applications

    The study and diverse applications of bioactive peptides traverse many sub-disciplines within chemistry, biology, physics, and medicine. Answering a long-standing need, Bioactive Peptides focuses on the biology, pharmacology, and therapeutic applications of endogenous peptide mediators and their analogues. Moving peptide science beyond chemical synthesis strategies and into the realms of peptide biology and therapeutics, it presents the overall contribution that peptide science has made to molecular, cellular, and whole organism biology, while also discussing future targets and therapeutic applications.

    Beneficial for Experts and Novices Alike

    Part I provides details of bioactive peptides that interact with common drug targets and analyzes some of the most competitive areas of current research worldwide. While it is widely known that mammalian physiological systems utilize bioactive peptides that have yet to be discovered, other animals provide a rich and valuable source of bioactive peptides. This fascinating area of science is the theme of Part II. Parts III and IV investigate the unique bioactivities of various peptides that are ripe for further exploration.

    This definitive reference also includes:

    • A detailed description and analysis of a broad range of peptides that interact with G protein-coupled receptors, the quantitatively dominant drug target

    • A discussion of non-ribosomal peptides, which hold promise as sources of endogenous mediators

    • Important examples of common methodologies employed to identify, characterize, and further develop bioactive peptides from a range of natural sources

    With mounting worldwide interest in their therapeutic potential, bioactive peptides—includ



    John Howl, Sarah Jones