1st Edition
Bioassay Techniques for Drug Development
240 Pages
by
CRC Press
240 Pages
by
CRC Press
Also available as eBook on:
The goal of an activity-directed isolation process is to isolate bioactive compounds which may provide structural leads of therapeutic importance. Whereas the traditional process of drug development is long and expensive, simple and rapid bioassays can serve as the starting point for drug discovery. This book presents a range of "bench top" bioassay techniques useful for natural product and... Read more
Part A. Bench-Top Primary Bioassay Screening. Toxicity Assays. Antimicrobial Assays. Antiviral and Anticancer Assays. Antimitotic Assay. Genotoxicity Assays. Assays for Control of Tropical Diseases. Assays for Agrochemicals. Hepatoxicity Assays. Hypoglycemic/Antidiabetic Activity Assays. Diuretic Activity Assays. Anthelminthic Assays. Anti-fertility/Anti-implantation Assay. In-vitro Assay for Platelet Aggregation. Anti-inflammatory Assay. Immunomodulating Assay. Antiepileptic (Anticonvulsant) Assay. Analgesic Assays. Gastroprotective/Antiulcer Assays. Radio-labeling Bioassays. Anti-emitic Assay. Part B. High-Throughput Screening. Enzyme Assays. Cell-based Receptor Functional Assays. Radioligand Binding Assays.
Biography
Atta-ur-Rahman, M. Iqbal Choudhary, William J. Thomsen
