Biochemical Applications of Nonlinear Optical Spectroscopy: 1st Edition (Paperback) book cover

Biochemical Applications of Nonlinear Optical Spectroscopy

1st Edition

Edited by Vladislav V. Yakovlev

CRC Press

290 pages | 150 B/W Illus.

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Description

For a host of reasons, nonlinear optical spectroscopy is a valuable tool for biochemical applications where minimally invasive diagnostics is desired. Biochemical Applications of Nonlinear Optical Spectroscopy presents the latest technological advances and offers a perspective on future directions in this important field.

Written by an international panel of experts, this volume begins with a comparison of nonlinear optical spectroscopy and x-ray crystallography. The text examines the use of multiphoton fluorescence to study chemical phenomena in the skin, the use of nonlinear optics to enhance traditional optical spectroscopy, and the multimodal approach, which incorporates several spectroscopic techniques in one instrument. Later chapters explore Raman microscopy, third-harmonic generation microscopy, and non-linear Raman microspectroscopy. The text explores the promise of beam shaping and the use of broadband laser pulse generated through continuum generation and an optical pulse shaper.

Lastly, the book discusses the effects of spatial beam shaping on the generated nonlinear Raman signals in a tightly focused geometry and provides insight into the extension of nonlinear optical spectroscopy to the nanoscale through the use of plasmonic tip-enhanced arrangement. With novel experimental approaches to this technology expanding day-by-day, the book’s balanced coverage from a wide range of international contributors not only elucidates important achievements, but also outlines future directions in this dynamic and promising field.

Table of Contents

Structural Dynamics and Kinetics of Myoglobin-CO Binding: Lessons from Time-Resolved X-ray Diffraction and Four-Wave Mixing Spectroscopy, V. Raicu, M. Schmidt, and M. Stoneman

Using Two-Photon Fluorescence Microscopy to Study Chemical Phenomena in the Skin, K.M. Hanson and C.J. Bardeen

Ultrafast Fluorescence Microscopes, T. Fujino and T. Tahara

Multicontrast Nonlinear Imaging Microscopy, R. Cisek, N. Prent, C. Greenhalgh, D. Sandkuijl, A. Tuer, A. Major, and V. Barzda

Broadband Laser Source and Sensitive Detection Solutions for Coherent Anti-Stokes Raman Scattering Microscopy, F. Ganikhanov

Nonlinear Optical Microspectroscopy of Biochemical Interactions in Microfluidic Devices, V. V. Yakovlev, G.I. Petrov, V. Shcheslavskiy, and R. Arora

Advanced Multiphoton and CARS* Microspectroscopy with Broadband Shaped Femtosecond Laser Pulses, B. von Vacano and M. Motzkus

Nonlinear Optical Imaging with Sub-10 fs Pulses, M. Dantus, D. Pestov, and Y. Andegeko

Imaging with Phase Sensitive Narrowband Nonlinear Microscopy, E.O. Potma and V.V. Krishnamachari

Biomolecular Imaging by Near-Field Nonlinear Spectroscopy and Microscopy, N. Hayazawa, T. Ichimura, K. Ikeda, and S. Kawata

About the Series

Optical Science and Engineering

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Subject Categories

BISAC Subject Codes/Headings:
SCI013060
SCIENCE / Chemistry / Industrial & Technical
SCI053000
SCIENCE / Optics
TEC019000
TECHNOLOGY & ENGINEERING / Lasers & Photonics