Biocontrol of Plant Diseases by Bacillus subtilis: Basic and Practical Applications, 1st Edition (Hardback) book cover

Biocontrol of Plant Diseases by Bacillus subtilis

Basic and Practical Applications, 1st Edition

By Makoto Shoda

CRC Press

326 pages | 100 B/W Illus.

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Hardback: 9780367136109
pub: 2019-10-01
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Plant diseases are a serious threat to food production. This unique volume provides the fundamental knowledge and practical use of B.subtilis as a promising biocontrol agent. In order to replace chemical pesticides, one possibility is microbial pesticides using safe microbes. Bacillus subtilis is one of several candidates. Screening of the bacterium, the application of plant tests, clarification of its suppressive mechanism to plant pathogens and engineering aspects of suppressive peptides production are presented here. The author illustrates how B. subtilis is far more advantageous than, for example, Pseudomonas in biocontrol and can be considered as an useful candidate.


  • Bacterium B. subtilis suppresses many plant pathogens and is a biocontrol agent to replace chemical pesticides
  • The book presents the bacterium's suppressive mechanism to plant pathogens, and engineering aspects of suppressive peptides production
  • Biological control of plant disease plays an important role in sustainable agricultural production practices and is expected to replace agricultural chemicals
  • Table of Contents

    In vitro selection of B. subtilis as a candidate of biocontrol agent; In vivo plant tests, including stability of B. subtilis in soil; Characterization of suppressive products to plant pathogens produced by B. subtilis; Biochemical and genetic analysis of B. subtilis related with production of three antibacterial and antifungal peptide substances; Engineering study of production of antibacterial and antifungal substances; comparison of submerged cultivation with solid-state cultivation and optimization; Co-use of B. subtilis with chemical pesticide; Mixed culture effect on biocontrol; Practical application of B. subtilis in some fruit gardens; Degradation characteristics of soybean curd residue by B. subtilis

    About the Author

    The author, Dr. M. Shoda, started his academic career with undergraduate, and graduate courses in Biochemical Engineering at the University of Tokyo, Tokyo, Japan. His Ph.D. thesis was on the modeling and computer simulation of product inhibition in microbial reactions under the supervision of Professor S. Aiba, who was a pioneer in Biochemical Engineering. This work on the introduction of computers to modeling was the first trial in the microbial world, and his scientific paper received 40th Anniversary Award for Papers with Special Impact on Biotechnology (John Wiley and Sons, Inc.).

    As assistant professor at Nagoya University, he gained experience in basic biochemistry and microbiology under the supervision of the late Professor S. Udaka, who was famous as the pioneer of producing amino acids using microbial reactions. He then moved to Tokyo Institute of Technology, where he concentrated on environmental biotechnology based on basic genetics and biochemistry, as well as computer control. As Director of the Research Laboratory of Resources Recycling Process, he supervised numerous graduate students who contributed to this book. He published more than 250 scientific papers, regarding isolation of several new microorganisms, including a new fungus that decomposes many toxic and colored chemicals by producing different unique enzymes, and a bacterium that converts ammonia directly to N2 gas without using conventional nitrification and denitrification processes at a 100-fold higher rate than the conventional method. He is active in research and application of microbial reactions as Professor Emeritus at Tokyo Institute of Technology.

    About the Series

    New Directions in Organic & Biological Chemistry

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    Subject Categories

    BISAC Subject Codes/Headings:
    MEDICAL / Pharmacology
    SCIENCE / Life Sciences / Botany
    SCIENCE / Chemistry / General
    SCIENCE / Environmental Science