Biodrug Delivery Systems : Fundamentals, Applications and Clinical Development book cover
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Biodrug Delivery Systems
Fundamentals, Applications and Clinical Development





ISBN 9781138116795
Published June 16, 2017 by CRC Press
488 Pages - 90 B/W Illustrations

 
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Book Description

Biodrug Delivery Systems: Fundamentals, Applications and Clinical Development presents the work of an international group of leading experts in drug development and biopharmaceutical science who discuss the latest advances in biodrug delivery systems and associated techniques. The book discusses components of successful formulation, delivery, and production of biodrugs, which include sophisticated plants and complex processes, a well-trained and knowledgeable staff, and proper quality control. In addition, the authors examine:

  • ADME (Absorption, Metabolism, Distribution, and Elimination of biodrugs)
  • Directing and influencing the successful development of currently marketed best-selling biodrugs
  • Routes of administration
  • Mechanisms of biodrug absorption
  • Alternative possibilities for drug delivery routes
  • Formulationson the market from the perspective of industry personnel involved in biodrug development

Table of Contents

Overview of Biodrug Delivery System
Issues in Biodrug Delivery System
Pharmacokinetic Consideration of Biodrugs
Specific Route of Delivery
Parenteral Delivery
Brain Delivery
Ocular Delivery
Nasal Delivery
Buccal Delivery
Pulmonary Delivery
Transdermal Delivery
Colon Delivery
Oral Delivery
Cellular Delivery
Delivery Systems
Targeting: PK Consideration
Monoclonal Antibody
Receptor-Mediated Endocytosis
Bioadhesive Delivery System
Modified Release Delivery System
Nanoparticulate Delivery System
Lipid-Based Delivery System
Implantable Delivery System
Modifying the Physiochemical Nature of Biodrugs
Regulatory Perspective of Biodrug Development
Development of Biodrug Products
Leuplin
ANP (Atrial Natriuretic Peptide)
Amylin And GLP-1 Agonists
GHRP-2 (Growth Hormone Releasing Peptide)
Endothelin Receptor Antagonist
Angiotensin II Receptor Antagonist
Insulin (Inhalation)
Calcitonin
Sandstatin LAR
Interferon
Vaccine
Perspective of Biodrug Products

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