Biofluid Mechanics: The Human Circulation, Second Edition, 2nd Edition (Hardback) book cover

Biofluid Mechanics

The Human Circulation, Second Edition, 2nd Edition

By Krishnan B. Chandran, Stanley E. Rittgers, Ajit P. Yoganathan

CRC Press

451 pages | 255 B/W Illus.

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Description

Designed for senior undergraduate or first-year graduate students in biomedical engineering, Biofluid Mechanics: The Human Circulation, Second Edition teaches students how fluid mechanics is applied to the study of the human circulatory system. Reflecting changes in the field since the publication of its predecessor, this second edition has been extensively revised and updated.

New to the Second Edition

  • Improved figures and additional examples
  • More problems at the end of each chapter
  • A chapter on the computational fluid dynamic analysis of the human circulation, which reflects the rapidly increasing use of computational simulations in research and clinical arenas

Drawing on each author’s experience teaching courses on cardiovascular fluid mechanics, the book begins with introductory material on fluid and solid mechanics as well as a review of cardiovascular physiology pertinent to the topics covered in subsequent chapters. The authors then discuss fluid mechanics in the human circulation, primarily applied to blood flow at the arterial level. They also cover vascular implants and measurements in the cardiovascular system.

Reviews

"… the book provides a good platform in fluid mechanics prior to progressing to the physiological applications which make it an appropriate textbook for BME students."

—Professor Tim McGloughlin, Centre for Applied Biomedical Engineering Research and Department of Mechanical Aeronautical and Biomedical Engineering, University of Limerick

Table of Contents

FLUID AND SOLID MECHANICS AND CARDIOVASCULAR PHYSIOLOGY

Fundamentals of Fluid Mechanics

Introduction

Intrinsic Fluid Properties

Hydrostatics

Macroscopic Balances of Mass and Momentum

Microscopic Balances of Mass and Momentum

Bernoulli Equation

Dimensional Analysis

Fluid Mechanics in a Straight Tube

Boundary Layer Separation

Introduction to Solid Mechanics

Introduction to Mechanics of Materials

Analysis of Thin-Walled Cylindrical Tubes

Analysis of Thick-Walled Cylindrical Tubes

Viscoelasticity

Cardiovascular Physiology

Introduction

Heart

Cardiac Valves

Systemic Circulation

Coronary Circulation

Pulmonary Circulation and Gas Exchange in the Lungs

Cerebral and Renal Circulations

Microcirculation

Regulation of the Circulation

Atherosclerosis

BIOMECHANICS OF THE HUMAN CIRCULATION

Rheology of Blood and Vascular Mechanics

Rheology of Blood

Vascular Mechanics

Summary

Static and Steady Flow Models

Introduction

Hydrostatics in the Circulation

Applications of the Bernoulli Equation

Rigid Tube Flow Models

Estimation of Entrance Length and Its Effect on Flow Development in Arteries

Flow in Collapsible Vessels

Summary

Unsteady Flow and Nonuniform Geometric Models

Introduction

Windkessel Models for the Human Circulation

Continuum Models for Pulsatile Flow Dynamics

Hemodynamic Theories of Atherogenesis

Wall Shear Stress and Its Effect on Endothelial Cells

Flow through Curved Arteries and Bifurcations

Flow through Arterial Stenoses and Aneurysms

Summary

Native Heart Valves

Introduction

Aortic and Pulmonary Valves

Mitral and Tricuspid Valves

CARDIOVASCULAR IMPLANTS, BIOMECHANICAL MEASUREMENTS, AND COMPUTATIONAL SIMULATIONS

Prosthetic Heart Valve Dynamics

Introduction

Brief History of Heart Valve Prostheses

Hemodynamic Assessment of Prosthetic Heart Valves

In Vitro Studies of Coagulation Potential and Blood Damage

Durability of Prosthetic Heart Valves

Current Trends in Valve Design

Conclusions

Vascular Therapeutic Techniques

Vascular Graft Implants

Arteriovenous Fistulas

Types of Vascular Graft Materials Used

Clinical Experience with Vascular Grafts

Biomechanics and Anastomotic IH

Angioplasty, Stent, and Endoluminal Graft Implants

Biomechanics of Stent Implants

Fluid Dynamic Measurement Techniques

Introduction

Blood Pressure Measurement

Blood Flow Measurement

Impedance Measurement

Flow Visualization

Ultrasound Doppler Velocimetry

Laser Doppler Velocimetry

MRI and Velocity Mapping Techniques

Computational Fluid Dynamic Analysis of the Human Circulation

Introduction

Computational Fluid Dynamic (CFD) Analysis Techniques

Modeling Considerations for Biofluid Mechanical Simulations

Fluid Dynamic Simulations in the Human Circulation

Future Directions: Multiscale Modeling

Summary

CFD Simulation Assignments

Index

Problems and References appear at the end of each chapter.

About the Authors

Krishnan B. Chandran is the Lowell G. Battershell Chair and professor in biomedical engineering, professor in mechanical and industrial engineering, and faculty research engineer in IIHR—Hydroscience & Engineering at the University of Iowa. His current research interests include vascular prosthesis and artificial heart valve dynamics, fluid dynamics and mass transport in arteries, and fluid dynamics and atherosclerosis.

Stanley E. Rittgers is a professor emeritus in biomedical engineering at the University of Akron. His research interests include cardiovascular hemodynamics, noninvasive diagnostics, ultrasound Doppler techniques, in vitro flow modeling, arterial bypass grafting, blood shear and vascular hyperplasia, and cardiovascular drug delivery.

Ajit P. Yoganathan is Regents’ Professor and associate chair for research, Wallace H. Coulter Distinguished Faculty Chair in biomedical engineering, and director of the Cardiovascular Fluid Mechanics Laboratory at Georgia Institute of Technology. His research areas include cardiovascular fluid dynamics, optimization of cardiovascular surgeries, surgical planning, tissue engineering of heart valves, and the use of MRI and 3D Echo to study blood flow patterns in cardiovascular structures.

Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
MED010000
MEDICAL / Cardiology
MED014000
MEDICAL / Clinical Medicine
SCI024000
SCIENCE / Energy
TEC009070
TECHNOLOGY & ENGINEERING / Mechanical