1st Edition

Bioinformatics and Human Genomics Research

Edited By Diego A. Forero Copyright 2022
    374 Pages 7 Color & 42 B/W Illustrations
    by CRC Press

    374 Pages 7 Color & 42 B/W Illustrations
    by CRC Press

    374 Pages 7 Color & 42 B/W Illustrations
    by CRC Press

    Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide
    expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.

    1. Bioinformatics and Human Genomics Research: An Introduction 
    Diego A. Forero and Yeimy González-Giraldo 
    2. Bioinformatics of Genome Annotation 
    Dinesh Gupta and Rahila Sardar 
    3. Protein Function Prediction: Human Sequences and Structures
    Sonal Modak and Jayaraman Valadi 
    4. Bioinformatics and Genomic Data Mining 
    Juan Camilo Ramírez 
    5. Bioinformatics of Genome-wide Expression Studies 
    Hugo Tovar, Diana E. Alvarez-Suarez, Laura Gómez-Romero and Enrique Hernández-Lemus 
    6. Whole-genome Sequencing: From Samples to Variants and Beyond   
    Jose M. Lorenzo-Salazar, Adrián Muñoz-Barrera, Rafaela González-Montelongo and Carlos Flores 
    7. Bioinformatics for Whole Exome Studies 
    Manojkumar Kumaran and Bharanidharan Devarajan 
    8. Bioinformatics of Variant Effect Prediction 
    Ariel José Berenstein, Franco Gino Brunello, Adrian Turjanski and Marcelo A. Martì 
    9. Bioinformatics of Genome-wide DNA Methylation Studies 
    Neeti Sharma and Anshika N. Singh 
    10. Bioinformatics of Transcription Factor Binding Prediction 
    Erick I. Navarro-Delgado, Marisol Salgado-Albarrán, Karla Torres-Arciga, Nicolas Alcaraz, Ernesto Soto-Reyes, Luis A. Herrera and Rodrigo González-Barrios 
    11. Bioinformatics of Prediction of Secondary Structures of Non-coding RNAs 
    S.S. Vinod Chandra 
    12. Bioinformatics of microRNA Target Prediction   
    Abdul Rawoof, Aviral Kumar, Shirish Tiwari and Lekha Dinesh Kumar 
    13. Bioinformatics and Network Analysis of Biological Data 
    Enrique Hernández-Lemus, Hugo Tovar, Laura Gómez-Romero and Mireya Martínez-García 
    14. Bioinformatics of Functional Categories Enrichment 
    Laura Gómez-Romero, Hugo Tovar and Enrique Hernández-Lemus 
    15. Bioinformatics of Meta-analyses of Genomic Data 
    Aditya Saxena 
    16. Clinical Data Integration with Cancer Genomics: Insights Into Computational and Quantitative Methods 
    Tábata Barbosa, Felipe Rojas-Rodríguez, Janneth Gonzalez and Andres Felipe Aristizabal-Pachón 
    17. Bioinformatics of Correction of Multiple Testing: An Introduction for Life Scientists (in Bioinformatics and Human Genomics Research) 
    Antonio Carvajal-Rodríguez 


    Diego A. Forero, MD, PhD is Professor and Research Leader at the School of Health and Sport Sciences, Fundación Universitaria del Área Andina (Bogotá, Colombia). He is a Medical Doctor (Universidad Nacional de Colombia, Colombia, 2003) and PhD in Biomedical Sciences (University of Antwerp, Belgium, 2009) and has a recognized track record in research on genetics and genomics. He has authored 107 international scientific publications, has a cumulative impact factor of 373,750 and a h-index of 27. He is Senior Editorial Member of BMC Research Notes, has been peer reviewer for 91 international scientific publications and for 28 academic and scientific institutions.