Bioinformatics and Human Genomics Research  book cover
1st Edition

Bioinformatics and Human Genomics Research

Edited By

Diego A. Forero




ISBN 9780367437602
Published January 7, 2022 by CRC Press
374 Pages 7 Color & 42 B/W Illustrations

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Book Description

Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in human and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide
expression studies and genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.

Table of Contents

1. Bioinformatics and Human Genomics Research: An Introduction 
Diego A. Forero and Yeimy González-Giraldo 
2. Bioinformatics of Genome Annotation 
Dinesh Gupta and Rahila Sardar 
3. Protein Function Prediction: Human Sequences and Structures
Sonal Modak and Jayaraman Valadi 
4. Bioinformatics and Genomic Data Mining 
Juan Camilo Ramírez 
5. Bioinformatics of Genome-wide Expression Studies 
Hugo Tovar, Diana E. Alvarez-Suarez, Laura Gómez-Romero and Enrique Hernández-Lemus 
6. Whole-genome Sequencing: From Samples to Variants and Beyond   
Jose M. Lorenzo-Salazar, Adrián Muñoz-Barrera, Rafaela González-Montelongo and Carlos Flores 
7. Bioinformatics for Whole Exome Studies 
Manojkumar Kumaran and Bharanidharan Devarajan 
8. Bioinformatics of Variant Effect Prediction 
Ariel José Berenstein, Franco Gino Brunello, Adrian Turjanski and Marcelo A. Martì 
9. Bioinformatics of Genome-wide DNA Methylation Studies 
Neeti Sharma and Anshika N. Singh 
10. Bioinformatics of Transcription Factor Binding Prediction 
Erick I. Navarro-Delgado, Marisol Salgado-Albarrán, Karla Torres-Arciga, Nicolas Alcaraz, Ernesto Soto-Reyes, Luis A. Herrera and Rodrigo González-Barrios 
11. Bioinformatics of Prediction of Secondary Structures of Non-coding RNAs 
S.S. Vinod Chandra 
12. Bioinformatics of microRNA Target Prediction   
Abdul Rawoof, Aviral Kumar, Shirish Tiwari and Lekha Dinesh Kumar 
13. Bioinformatics and Network Analysis of Biological Data 
Enrique Hernández-Lemus, Hugo Tovar, Laura Gómez-Romero and Mireya Martínez-García 
14. Bioinformatics of Functional Categories Enrichment 
Laura Gómez-Romero, Hugo Tovar and Enrique Hernández-Lemus 
15. Bioinformatics of Meta-analyses of Genomic Data 
Aditya Saxena 
16. Clinical Data Integration with Cancer Genomics: Insights Into Computational and Quantitative Methods 
Tábata Barbosa, Felipe Rojas-Rodríguez, Janneth Gonzalez and Andres Felipe Aristizabal-Pachón 
17. Bioinformatics of Correction of Multiple Testing: An Introduction for Life Scientists (in Bioinformatics and Human Genomics Research) 
Antonio Carvajal-Rodríguez 

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Editor(s)

Biography

Diego A. Forero, MD, PhD is Professor and Research Leader at the School of Health and Sport Sciences, Fundación Universitaria del Área Andina (Bogotá, Colombia). He is a Medical Doctor (Universidad Nacional de Colombia, Colombia, 2003) and PhD in Biomedical Sciences (University of Antwerp, Belgium, 2009) and has a recognized track record in research on genetics and genomics. He has authored 107 international scientific publications, has a cumulative impact factor of 373,750 and a h-index of 27. He is Senior Editorial Member of BMC Research Notes, has been peer reviewer for 91 international scientific publications and for 28 academic and scientific institutions.