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Bioinformatics and Human Genomics Research

Edited By

Diego A. Forero



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ISBN 9780367437602
August 15, 2021 Forthcoming by CRC Press
290 Pages 8 Color & 50 B/W Illustrations

 
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Book Description

Advances in high-throughput biological methods have led to the publication of a large number of genome-wide studies in humans and animal models. In this context, recent tools from bioinformatics and computational biology have been fundamental for the analysis of these genomic studies. The book Bioinformatics and Human Genomics Research provides updated and comprehensive information about multiple approaches of the application of bioinformatic tools to research in human genomics. It covers strategies analysis of genome-wide association studies, genome-wide expression studies, genome-wide DNA methylation, among other topics. It provides interesting strategies for data mining in human genomics, network analysis, prediction of binding sites for miRNAs and transcription factors, among other themes. Experts from all around the world in bioinformatics and human genomics have contributed chapters in this book. Readers will find this book as quite useful for their in silico explorations, which would contribute to a better and deeper understanding of multiple biological processes and of pathophysiology of many human diseases.

Table of Contents

Bioinformatics and Human Genomics Research: An Introduction

Diego A. Forero, Yeimy González-Giraldo, [email protected]

Bioinformatics of Gene Annotation

Dinesh Gupta, Rahila Sardar, [email protected]

Protein Function Prediction: Human Sequences and Structures

Sonal Modak and Jayaraman Valadi, [email protected]

Bioinformatics and Genomic Data Mining

Juan Camilo Ramírez, [email protected]

Bioinformatics of Genome-Wide Expression Studies

Hugo Tovar, Diana E. Alvarez-Suarez, Laura Gómez-Romero, Enrique Hernández-Lemus

[email protected]

Whole-Genome Sequencing: From Samples to Variants and Beyond

José M. Lorenzo-Salazar, Adrián Muñoz-Barrera, Rafaela González-Montelongo, Carlos Flores, [email protected]

Bioinformatics for Whole Exome Studies

Manojkumar Kumaran, Bharanidharan Devarajan, [email protected]

Bioinformatics of Variants Effect Prediction

Ariel José Berenstein, Franco Gino Brunello, Adrian Turjanski, Marcelo A Martì

[email protected]

Bioinformatics of Genome-Wide DNA Methylation Studies

Neeti Sharma, Anshika N. Singh, [email protected]

Bioinformatics of Transcription Factor Binding Prediction

Erick I. Navarro-Delgado, Marisol Salgado-Albarrán, Karla Torres-Arciga, Nicolas Alcaraz, Ernesto Soto-Reyes, Luis A. Herrera, Rodrigo González-Barrios

[email protected]

Bioinformatics of Prediction of Secondary Structures of Non-Coding RNAs

Vinod Chandra, [email protected]

Bioinformatics of Microrna Target Prediction

Abdul Rawoof, Aviral Kumar, Shirish Tiwari, Lekha Dinesh Kumar, [email protected]

Bioinformatics and Network Analysis of Biological Data

Enrique Hernández-Lemus, Hugo Tovar, Laura Gómez-Romero, Mireya Martínez-García

[email protected]

Bioinformatics of Functional Categories Enrichment

Laura Gómez-Romero, Hugo Tovar, Enrique Hernández-Lemus, [email protected]

Bioinformatics of Meta-Analyses of Genomic Data

Aditya Saxena, [email protected]

Clinical Data Integration with Cancer Genomics: Insights of Computational and Quantitative Methods

Tábata Barbosa, Felipe Rojas-Rodríguez, Janneth Gonzalez, Andrés Felipe Aristizabal-Pachón, [email protected]

Bioinformatics of Correction of Multiple Testing  

Antonio Carvajal-Rodríguez, [email protected]

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Editor(s)

Biography

Dr. Diego A. Forero, MD, PhD is a Full Professor and Director of the PhD Program in Health Sciences at the Medical School, Universidad Antonio Nariño (Bogotá, Colombia). He is Medical Doctor (Universidad Nacional de Colombia, Colombia, 2003) and PhD in Biomedical Sciences (University of Antwerp, Belgium, 2009) and has a recognized track record in research on neuropsychiatric genetics. He has authored 81 international scientific publications, has a cumulative impact factor of 209,663 and an h-index of 23. He is Associate Editor of BMC Research Notes, has been peer reviewer for 67 international scientific publications and for 23 academic and scientific institutions.