1st Edition

Bioinformatics for Oral Cancer Current Insights and Advances

    114 Pages 16 Color Illustrations
    by CRC Press

    Amid the rising global concern of oral cancer, this book provides a compelling exploration of the intricate oral cavity, focused on shedding light on early diagnosis and addressing outdated paradigms, it delves into the persistent challenges of oral premalignant lesions. Tailored for both beginners and researchers, its six chapters encompass the spectrum of genome sequencing, diagnostic biomarkers, gene expression, and more. Discover a fusion of basic and clinical sciences, aiming to invigorate the study of bioinformatics and oral cancer, and ultimately improve survival rates.

    Bioinformatics for Oral Cancer: Current Insights and Advances serves as a comprehensive guide, offering a deep dive into the multifaceted landscape of oral cancer research and bioinformatics. Within its pages, readers will uncover a wealth of knowledge, starting with foundational chapters introducing bioinformatics and establishing the backdrop of oral cancer. The book then progresses into the realm of diagnostic biomarkers, revealing cutting-edge methodologies for their identification in the context of oral cancer. The book’s keen focus extends to gene expression profiles and the intricacies of gene sequencing in the context of oral cancer progression. By systematically unravelling these critical aspects, the book bridges the gap between basic and clinical sciences, equipping readers with a holistic understanding of bioinformatics’ pivotal role in enhancing our grasp of oral cancer’s complexities.

    By deciphering the enigmatic landscape of oral premalignant lesions, the book equips clinicians and researchers with tools to predict malignant potentials. Its meticulous exploration of gene expression profiles and sequencing promises to reshape early detection strategies, propelling the field towards improved diagnosis and treatment outcomes.

    Chapter 1: Introduction to Bioinformatics
    Viveka S, Bhargav Shreevatsa, Kavana CP, Chandan Dharmashekara, Mahesh KP, Shiva Prasad Kollur, Chandan Shivamallu

    Chapter 2: Background of Oral Cancer
    Viveka S, Bhargav Shreevatsa, Kavana C P, Chandan Dharmashekara, Bhavana H H, Sumitha.E, Mahesh KP, Shiva Prasad Kollur, Chandan Shivamallu

    Chapter 3: Biomarkers as a Diagnostic Tool
    Bhargav Shreevatsa, Viveka S, Sai Chakith M R, Chandan Dharmashekara, Siddesh V Siddalingegowda, Umamaheswari, Mahesh KP, Shiva Prasad Kollur, Chandan Shivamallu

    Chapter 4: Methodologies for Identifying Oral Cancer Biomarkers
    Bhargav Shreevatsa, Viveka S, Sai Chakith M R, Ashwini Prasad, Umamaheswari, Mahesh KP, Shiva Prasad Kollur, Chandan Shivamallu

    Chapter 5: Gene Expression Profile in OSCC
    Viveka S, Bhargav Shreevatsa, Kavana CP, Chandan Dharmashekara, Ashwini Prasad, Mahesh KP, Shiva Prasad Kollur, Chandan Shivamallu

    Chapter 6: Next Genome Sequencing in Oral Cancer
    Bhargav Shreevatsa, Viveka S, Sai Chakith M R, Chandan Dharmashekara, Siddesh V Siddalingegowda, Mahesh KP, Shiva Prasad Kollur, Chandan Shivamallu


    Dr. Mahesh K P is an Associate Professor specializing in oral diagnostics and radiology at JSS Dental College and Hospital, JSS AHER, Mysuru, India. With a teaching journey spanning 17 years, dedicated to both educating and researching in diverse areas of dentistry. Achievements include receiving the Asia Pacific Young Achiever Award (Education Sector) from Belgave and the Commonwealth Vocational Services (Education Sector) recognition in 2019, authoring 45 publications, securing three patents, and authoring two textbooks along with a textbook chapter in the field of dentistry.

    Raghavendra Amachawadi, also known as Raghu, holds the position of an Associate Professor of Food Animal Therapeutics, Department of Clinical Sciences at the College of Veterinary Medicine, Kansas State University. Raghu’s journey began with a BVSc degree from the Veterinary School in Bangalore, India, which is comparable to a DVM degree. In 2008, a new chapter began by coming to the United States earning from Kansas State University an MS degree in 2010, followed by a PhD in Microbiology/ Epidemiology in 2014.

    Shiva Prasad Kollur is an Associate Professor in the field of Chemistry at Amrita Vishwa Vidyapeetham, located in Mysuru, India. Academic pursuits have centred around the realms of Bioinorganic and Materials Chemistry. Professor Kollur has contributed significantly to the scientific community, authoring and publishing over 120 research articles in prestigious international peer-reviewed journals as well as successfully patented research discoveries. Another gratifying aspect has been the role of mentor, having the privilege of guiding more than 40 scholars, both at the graduate and postgraduate levels, in their pursuit of academic accomplishments.

    Chandan S, Deputy Dean of Research and Associate Professor at JSS AHER, is an accomplished researcher with an exceptional 15-year track record in the world of academia. His journey is marked by numerous accolades, including the highly prestigious Young Scientist Award conferred by the Department of Science and Technology. He has authored an impressive 248 international publications, reflecting his unwavering commitment to advancing knowledge in his field. Beyond publications, he has also secured five patents, underlining his innovative contributions to research. Importantly, his work has gone beyond theory, resulting in the creation of three prototypes. Mentorship and education are integral aspects of Chandan S's career. He has successfully guided four PhD students. Currently, he continues to mentor six more students, further highlighting his commitment to fostering academic excellence. Professor Chandan S's work exemplifies a multifaceted commitment to research, mentorship, and innovation. His diverse research interests and collaborative efforts not only enrich the academic community but also contribute significantly to the broader advancement of knowledge in his field. His impressive career, complemented by a plethora of awards and recognitions, solidifies his status as a leading figure in research and academia.