This book, a part of the series Studies in Medicinal Chemistry, details the biological inhibitors that reflect drug discovery in treating human diseases, including cardiovascular, nervous, inflammatory, hormonal and metabolic processes. Compounds for fungal diseases and HIV/AIDS are also covered.
Table of Contents
1. Medicinal Chemistry of Squalene Epoxidase Inhibitors 2. Dual Inhibitors of 5-Lipoxygenase and Cyclooxygenase 3. Inhibitors of Cholesterol Biosynthesis 4. The Design and Synthesis of Inhibitors of HIV Proteinase 5. Nonpeptide Antagonists at Peptide Receptors 6. Conformations and Binding Interactions of Thyroid Hormones and Analogues 7. Chemical and Computer Assisted Development of an Inclusive Pharmacophore for the Benzodiazepine Receptor