Biology and Physiology of the Osteoclast is a comprehensive volume thoroughly covering the field of osteoclast biology. The book features some of the latest work (much of which has never before been published) from internationally respected scientists in the field. It will be a significant reference volume for researchers interested in the broad field of bone metabolism, especially those in cell and molecular biology, dental science, endocrinology, hematology, orthopedics, and rheumatology.
Experimental Systems for Studying Osteoclast Biology (P. Osdoby, M. Krukowski, and P. Collin-Osdoby). Antigenic Markers of Osteoclasts (M.A. Horton and M.H. Helfrich). Acid Phosphatases (G. Andersson, B. Ek-Rylander, and C. Minkin). Ontogeny of the Osteoclast (P.J. Nijweide and R. de Grooth). Regulation of Osteoclast Development and Function (T.J. Chambers). Osteoclast Ultrastructure and Enzyme Histochemistry: Functional Implications (C.V. Gay). Systematic Factors Regulating Osteoclast Function (J.N.M. Heersche). Local Factors Regulating Osteoclast Function (G.R. Mundy). The Influence of Matrix Components on Osteoclasts (J. Glowacki). Signal Transduction Mechanisms in Osteoclasts (H.J. Donahue). Electrophysiology of Osteoclasts (S.M. SIms, M.E.M. Kelly, S.A. Arkett, and S.J. Dixon). Osteoclast Cytoskeleton and Attachment Proteins (A. Teti and A. Zambonin-Zallone). The Mechanism of Osteoclast Acidification (H.C. Blair and P.H. Schlesinger). Mechanism of Mineral Solubilization and Matrix Degradation in Osteoclastic Bone Resorption (J.-M. Delaissé and G. Vaes). Reactive Oxygen Species as Potential Mediators of Osteoclast Action (R.A. Greenwald and B.R. Rifkin). Osteoblast/Osteoclast Coupling (J.E. Puzas and M. Ishibe). Effects of Pharmacological Agents on Osteoclasts (P.H. Stern and P. Lakatos). Bisphosphonates (P.H. Schlesinger and H.C. Blair). . Mechanical Effects on Osteoclast Function (E.H. Burger). Osteopetrosis (L.K. Osier and S.C. MArks, Jr.). The Osteoclast in Paget's Disease of Bone (G. David Roodman). Index.