The NMDA receptor plays a critical role in the development of the central nervous system and in adult neuroplasticity, learning, and memory. Therefore, it is not surprising that this receptor has been widely studied. However, despite the importance of rhythms for the sustenance of life, this aspect of NMDAR function remains poorly studied. Written by one of the world’s leading authorities on NMDA receptors, Biology of the NMDA Receptor brings together virtually all the players in this important field.
Introduction. Molecular Genetics of the NMDA Receptor. NMDA Receptors: Learning and Memory. The Role of NMDA Receptors in Organizing Brain Development. NMDA Receptors and Developmental Critical Periods. NMDA Receptors and Spine Morphogenesis. NMDA Receptors and Synaptic Plasticity. NMDA Receptor Signaling to the Nucleus. Trafficking and Targeting of NMDA Receptors. Regulation of NMDA Receptor Function by Phosphorylation. Allosteric Modulation of the NMDA Receptor. Pharmacology of the NMDA Receptor. Activation of the NMDA Receptor. Structural Biology of the NMDA Receptor.