Biomaterials: A Nano Approach, 1st Edition (Hardback) book cover

Biomaterials

A Nano Approach, 1st Edition

By Seeram Ramakrishna, Murugan Ramalingam, T .S. Sampath Kumar, Winston O. Soboyejo

CRC Press

372 pages | 133 B/W Illus.

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Hardback: 9781420047813
pub: 2010-06-14
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Description

There are several well-known books on the market that cover biomaterials in a general way, but none provide adequate focus on the future of and potential for actual uses of emerging nanontechnology in this burgeoning field.

Biomaterials: A Nano Approach is written from a multi-disciplinary point of view that integrates aspects of materials science and engineering, nanotechnology, bioengineering, and biosciences. The book fills a glaring void in the literature by providing a comprehensive discussion of biomaterials and a scientifically plausible extrapolation of likely scenarios in which nanotechnology could play a significant role. The authors introduce and examine basic concepts, processing methodologies, and techniques involved in the preparation and characterization of nanobiomaterials that are specific to biomedical applications.

A Self-Contained Book Illustrating Past, Present, and Future Trends in Biomaterials

Spanning from the historical development of biomaterials to cutting-edge advances in the field, the text describes how basic concepts in nanotechnology are applied to the processing of novel nanobiomaterials, including nanostructured metals and alloys. With its illustrative examples and presentation of applications, this text offers a solid framework for understanding present and future trends of biomaterials in human healthcare systems. It is an ideal companion resource for students, researchers, and industrial scientists who specialize in biomaterials and nanobiomaterials.

Table of Contents

Overview of Biomaterials

Introduction

Biomaterials: From Then to Now

Impact of Biomaterials

Characteristics of Biomaterials

Classification of Biomaterials

Surface Modification of Biomaterials

Recent Trends in Biomaterials

Summary

Glossary

References

Basics of Human Biology

Introduction

Structure and Function of the Human Body

Chemical Level

Cellular Level

Tissue Level

Organ Level

System Level

Glossary

References

Further Reading

Degradation and Corrosion of Biomaterials

Introduction

Surface Properties

Degradation of Biomaterials

Corrosion of Biomaterials

Methods of Corrosion Testing

Biocompatibility of Implants

Case Study

Summary

Glossary

References

Further Reading

Failure and Tribology of Biomaterials

Introduction

Deformation Mechanics

Deformation Analysis of Biomaterials

Fracture Mechanics

Classification of Fracture

Brittle to Ductile Transition of Biomaterials

Fracture Toughness

Toughness Analysis of Biomaterials

Fatigue Mechanics

Fatigue Analysis of Biomaterials

Tribology

Tribological Analysis of Biomaterials

Case Study

Summary

Glossary

References

Further Reading

Nanoscale Phenomena

Introduction

Nanoscale Phenomena

Processing of Nanostructured Materials

Characterization Techniques

Environmental and Safety Aspects of Nanomaterials

Summary

Glossary

References

Further Reading

Metallic Biomaterials

Introduction

Metallic Biomaterials

Nanostructured Metallic Implants

Case Study

Summary

Glossary

References

Ceramic Biomaterials

Introduction

Bioceramics

Nanostructured Bioceramics

Synthesis and Characterization of Nano Bioceramics

Case Study

Summary

Glossary

References

Polymeric Biomaterials

Introduction

Polymers as Biomaterials

Classification of Polymeric Biomaterials

Naturally Derived Polymers

Synthetic Polymers

Polymeric Nanobiomaterials

Processing of Polymer Nanofibers: Current Scenarios

Electrospun Polymer Nanofibrous Scaffolds

Biomedical Applications of Polymer Nanofibers

Summary

Glossary

References

Composite Biomaterials

Introduction

Classification of Composite Biomaterials

Biological Responses to Composite Biomaterials

Biomedical Applications of Composite Biomaterials

Evolution of Nanocomposite Biomaterials

Nanocomposites: A New Class of Nanobiomaterials

Conventional Nanocomposites

Biomimetic Nanocomposites

Tissue-Engineered Nanocomposites

Nanocomposites for Growth Factor Delivery

Summary

Glossary

References

Nanobiomaterials for Tissue Regeneration

Introduction

Concept of Tissue Engineering

The Promise of Stem Cells

Nanobiomaterials: A New Generation Scaffolding Material

Characteristics of a Scaffold

Types of Scaffolding Materials

Scaffold Designing using Nanobiomaterials

Tissue-Engineered Ceramic Nanobiomaterials

Tissue-Engineered Polymeric Nanobiomaterials

Patterning of Biomaterials for Cell Engineering

Tissue-Engineered Products: The Artificial Skin and Cartilage

Case Study

Summary

Glossary

References

Index

About the Authors

Dr. Seeram Ramakrishna is a professor of Mechanical Engineering and Bioengineering at the National University of Singapore (NUS). He is also Vice-President (Research Strategy) of NUS. He is the founding co-director of NUS Nanoscience & Nanotechnology Initiative (NUSNNI). His current research interests include biomaterials, tissue engineering and nanotechnology. He is advancing the materials science, manufacturing technology, and design aspects of nanobiomaterials to realize their full potential in human health care. His research output appeared in over 400 publications. The ISI Essential Science Indicators (ESI) places him among the top 110 materials scientists in the world based on citations. These include several peer-reviewed journal publications, book chapters, books and patents. He is board member of fifteen international journals. He is a scientific advisory board member to biomedical companies, Stem Life and Biomers International.

Dr. Murugan Ramalingam is a NRC Associate at the National Institute of Standards and Technology (NIST), USA, working under the United States National Research Council’s joint NIH/NIST program. He joined the NIST after completion of postdoctoral training at the Nano Science and Technology Center (NSTC), University of Central Florida, USA. His main research interests are the development of multiphase biomaterials, through conventional to biomimetics and tissue engineering approaches. He has authored several peer-reviewed journal articles, book chapters, and patents relevant to micro-/nano-biomaterials.

Dr. T.S. Sampath Kumar is an associate professor of Metallurgical and Materials Engineering at the Indian Institute of Technology Madras, India. His research interests are on nanobioceramics, functionally graded biomaterials, novel ceramic coatings and ceramic based drug delivery systems. He is currently the Secretary of the Society for Biomaterials and Artificial Organs-India (SBAOI). He is the associate editor of the SBAOI journal of "Trends in Biomaterials and Artificial Organs-India"during 2002-2005, and continues to be on its editorial board since 1991. He has published 3 issues of this journal and an issue of the "Transactions of the Indian Institute of Metals" journal as a guest editor.

Wole Soboyejo received his Bachelor of Science degree in Mechanical Engineering from King’s College London in 1985, and a Ph.D. in materials science from Cambridge University in 1988. He then worked as a research scientist at the McDonnell Douglas Research Labs from 1988 until 1992. He worked briefly as a Principal Research Engineer at the Edison Welding Institute before joining the faculty in the department of materials science and engineering at The Ohio State University in 1992. He was a Visiting Martin Luther King Associate Professor in the departments of mechanical engineering and materials science and engineering at MIT from 1997 to 1998. In 1999, he moved to Princeton University as a professor of mechanical and aerospace engineering, and a faculty member in the Princeton Institute of Science and Technology of Materials (PRISM). He is the recipient of 2 National Young Investigator Awards (NSF and ONR), the Lumley Research Award of the Ohio State University and the Bradley Stoughton Award for young teachers of materials science. Professor Soboyejo is a Fellow of ASME and the Nigerian Academy of Science. He has published 250 journal papers and a textbook on the Mechanical Properties of Engineered Materials. He has also edited a recent text on Advanced Structural Materials and 18 special issues of journals/conference proceedings.

Subject Categories

BISAC Subject Codes/Headings:
MED009000
MEDICAL / Biotechnology
TEC021000
TECHNOLOGY & ENGINEERING / Material Science