© 2013 – CRC Press
662 pages | 29 Color Illus. | 84 B/W Illus.
Focused on stem cell applications, this book bridges the fields of biomaterials, offering new insights into constructing and regenerating tissues and organs. Its unique feature is linking diseases of the human body to current thinking on how to deal with them in the context of current concepts and technologies by means of an in-depth focus on biomaterials. The book assembles recent advances and covers a range of topics related to stem cell biology, biomaterials and technological approaches such as bioreactors written by top researchers in the field. Stem cells of both embryonic and adult origin are discussed with applications ranging, but not limited to, nerve regeneration, liver, pancreas, skin, trachea, cartilage and bone repair and cardiovascular therapy. Developments in the field reflecting the design and construction of the human body and its principal anatomy are discussed from a materials point of view.
The book will be a valuable tool for biomaterial scientists, tissue engineers, clinicians as well as stem cell biologists involved in basic research and applications of adult and embryonic stem cells. It will also be a source of reference for students in biotechnology, biomedical engineering, biology, biochemistry, materials sciences, pharmaceuticals, and veterinary and human medicine.
Synthetic Polymer-Network Based Materials in Stem Cell Research
Adam L. Sisson and Andreas Lendlein
Membrane Systems in Liver Regenerative Medicine
Simona Salerno, Loredana De Bartolo, and Enrico Drioli
Blood-derived biomaterials: what role can they play in regenerative medicine and stem cell therapy ?
Chen-Yao Su and Thierry Burnouf
Pectins as Future Biomaterials
Hanna Kokkonen and Juha Tuukkanen
Biointerfaces between Biomaterials and Biosystems in Tissue Engineering: Potential Contributions of Two-Photon Polymerization and Polyelectrolyte Multilayer Coatings
S. Grohmann, T.Weiß, and K. Liefeith
Sabrina Morelli and Antonella Piscioneri
Bone Marrow Stem Cells
Xuetao Pei, Wen Yue, Junnian Zhou, Xinlong Yan, Jingxue Wang, Jiafei Xi, Haiyun Pei, and Hailei Yao
Umbilical Cord Matrix Cells–Promising Instrument For Regenerative Medicine
Maslova O.O., Deryabina O.G., and Kordium V.A.
Cellular Properties of Mesenchymal Cells Derived from the Decidua of Human Term Placenta and Their Applications in Regenerative Medicine
Daisuke Kanematsu and Yonehiro Kanemura
Adipose Tissue: a New Source of Hepatic Cells.
Ana Bonora-Centelles, Ramiro Jover Atienza, Vicente Mirabet Lis, José Vicente Castell Ripoll, and MªJosé Gómez-Lechón
Engineering Biomimetic Microenvironments Using Biomaterials, Soluble Signals for Ex Vivo Expansion and Differentiation of Stem Cells: Strategic Challenges For Creation of Clinical Grades for Stem Cell Therapy
Shibashish Giri and Augustinus Bader
Yuji Teramura and Hiroo Iwata
Trachea and Larynx in Regenerative Medicine
Silvia Baiguera, M. Jaus, A. Gonfiotti, and Paolo Macchiarini
Organ Printing: a Novel Tissue Engineering Paradigm
Francoise Marga, Karoly Jakab, IoanKosztin, and Gabor Forgacs
Stem Cell Microencapsulation for Therapeutic Angiogenesis
Clara Sanz Nogués, Dilip Thomas, Abhay Pandit, and Timothy O’Brien
Microencapsulation and Bioreactors for Liver Support
Murielle Dufresne, Nhu Mai Tran, Stéphanie Capone, Martine Daujat, and Cecile Legallais
Mass Transfer and Computational Fluid-Dynamics in Bioreactors
Efrem Curcio and Loredana De Bartolo
Innovative Solutions for Wound Therapy
Christina Irene Günter and Hans-Günther Machens
Neuroprotection and Neuroregeneration Strategies for Neurodegenerative Diseases
Membrane Emulsification for Cell Delivery
Emma Piacentini, Enrico Drioli, and Lidietta Giorno
Regulations and Ethical Issues
GMP Requirements and Quality Management of Cellular Products
Markus Neubauer and Saskia Knothe
From Laboratory Bench to Registration and Marketing Approval: Clinical Development for the Biomaterial Developer
The Tension between Conflicting Fundamental Values: The Ethical Challenge of Embryonic Stem Cell Research