Biomedical Applications of Computer Modeling: 1st Edition (Hardback) book cover

Biomedical Applications of Computer Modeling

1st Edition

Edited by Arthur Christopoulos

CRC Press

264 pages

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Hardback: 9780849301001
pub: 2000-09-19
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Up to the last decade or so, most general modeling approaches to the study of molecular components of biological responses have required significant amount of computer time, expertise, and resources, as well as highly specialized and often custom-written programs. With Biomedical Applications of Computer Modeling you don't have to be a computer scientist to learn valuable modeling techniques.

The book represents the first single-volume book that describes general approaches to computer modeling as they apply to the biomedical professions, particularly in the realms of pharmacology and biochemistry. Bringing together contributions from researchers with hands-on expertise, the book is loaded with examples, and it also encompasses different types of computer modeling approaches. In fact, the text supports each modeling approach with clinical examples. It thereby provides a convenient source of readily applicable modeling information. In addition, the book offers easy-to-follow information and presents it in a how-to manner that minimizes the use of mathematical jargon.

Biomedical Applications of Computer Modeling includes chapters on equilibrium modeling, dynamic/kinetic modeling, and stochastic modeling, as well as overviews of the application of models to experimental data. With the ubiquitous presence of desktops and notebook computers in biomedical environments, Biomedical Applications of Computer Modeling provides you with an unprecedented means for readily addressing data analysis or computer modeling problems.

Table of Contents

The Pharmacological Consequences of Modeling Synoptic Receptor Systems

The Ternary Complex Model

From the Static to the Dynamic: 3 Models of Signal Transduction in G Protein Coupled Receptors

Intramolecular Dynamics and Ligand-Induced Conformational Changes: A Stochastic Model of Receptor Action

Linking Bioinformatics and Cheminformatics: From Genes to Structure-Activity Relationships

Computer-Intensive Statistical Procedures

Beyond Eyeballing: Fitting Models to Experimental Data

About the Series

Handbooks in Pharmacology and Toxicology

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Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Biochemistry
MEDICAL / Pharmacology
SCIENCE / Biotechnology