Biomedical Engineering Fundamentals  book cover
2nd Edition

Biomedical Engineering Fundamentals

ISBN 9781138748071
Published February 26, 2018 by CRC Press
1180 Pages

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Book Description

Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.

Biomedical Engineering Fundamentals, the first volume of the handbook, presents material from respected scientists with diverse backgrounds in physiological systems, biomechanics, biomaterials, bioelectric phenomena, and neuroengineering.

More than three dozen specific topics are examined, including cardiac biomechanics, the mechanics of blood vessels, cochlear mechanics, biodegradable biomaterials, soft tissue replacements, cellular biomechanics, neural engineering, electrical stimulation for paraplegia, and visual prostheses. The material is presented in a systematic manner and has been updated to reflect the latest applications and research findings.

Table of Contents


An Outline of Cardiovascular Structure and Function; Daniel J. Schneck

Kidney Structure and Physiology; Joel M. Henderson and Mostafa Belghasem

Nervous System; Evangelia Micheli-Tzanakou

Vision System; Aaron P. Batista and George D. Stetten

Auditory System; Ben M. Clopton and Herbert F. Voigt

Gastrointestinal System; Berj L. Bardakjian

Respiratory System; Arthur T. Johnson, Christopher G. Lausted, and Joseph D. Bronzino


Mechanics of Hard Tissue; J. Lawrence Katz, Anil Misra, Orestes Marangos, Qiang Ye, and Paulette Spencer

Musculoskeletal Soft-Tissue Mechanics; Richard L. Lieber, Samuel R. Ward, and Thomas J. Burkholder

Joint-Articulating Surface Motion; Kenton R. Kaufman and Kai-Nan An

Joint Lubrication; Michael J. Furey

Analysis of Gait; Roy B. Davis, III, Sylvia Õunpuu, and Peter A. DeLuca

Mechanics of Head/Neck; Albert I. King and David C. Viano

Biomechanics of Chest and Abdomen Impact; David C. Viano and Albert I. King

Cardiac Biomechanics; Andrew D. McCulloch and Roy C.P. Kerckhoffs

Heart Valve Dynamics; Choon Hwai Yap, Erin Spinner, Muralidhar Padala, and Ajit P. Yoganathan

Arterial Macrocirculatory Hemodynamics; Baruch B. Liber

Mechanics of Blood Vessels; Thomas R. Canfield and Philip B. Dobrin

The Venous System; Artin A. Shoukas and Carl F. Rothe

The Microcirculation Physiome; Aleksander S. Popel and Roland N. Pittman

Mechanics and Deformability of Hematocytes; Richard E. Waugh and Robert M. Hochmuth

Mechanics of Tissue/Lymphatic Transport; Geert W. Schmid-Schönbein and Alan R. Hargens

Modeling in Cellular Biomechanics; Alexander A. Spector and Roger Tran-Son-Tay

Cochlear Mechanics; Charles R. Steele and Sunil Puria

Inner Ear Hair Cell Bundle Mechanics; Jong-Hoon Nam and Wally Grant

Exercise Physiology; Cathryn R. Dooly and Arthur T. Johnson

Factors Affecting Mechanical Work in Humans; Ben F. Hurley and Arthur T. Johnson


Metallic Biomaterials; Joon B. Park and Young Kon Kim

Ceramic Biomaterials; W.G. Billotte

Polymeric Biomaterials; Hai Bang Lee, Gilson Khang, and Jin Ho Lee

Composite Biomaterials; Roderic S. Lakes

Biodegradable Polymeric Biomaterials: An Updated Overview; C.C. Chu

Biologic Biomaterials: Tissue-Derived Biomaterials (Collagen); Shu-Tung Li

Biologic Biomaterials: Silk; Biman Mandal and David L. Kaplan

Biofunctional Hydrogels; Melissa K. McHale and Jennifer L. West

Soft Tissue Replacements; K.B. Chandran, K.J.L. Burg, and S.W. Shalaby

Hard Tissue Replacements; Sang-Hyun Park, Adolfo Llinás, and Vijay K. Goel


Basic Electrophysiology; Roger C. Barr

Volume Conductor Theory; Robert Plonsey

Electrical Conductivity of Tissues; Bradley J. Roth

Cardiac Microimpedances; Andrew E. Pollard

Membrane Models; Anthony Varghese

Computational Methods and Software for Bioelectric Field Problems; Christopher R. Johnson

The Potential Fields of Triangular Boundary Elements; A. van Oosterom

Principles of Electrocardiography; Edward J. Berbari

Electrodiagnostic Studies; Sanjeev D. Nandedkar

Principles of Electroencephalography; Joseph D. Bronzino

Biomagnetism; Jaakko Malmivuo

Electrical Stimulation of Excitable Tissue; Dominique M. Durand


History and Overview of Neural Engineering; Daniel DiLorenzo and Robert E. Gross

Theory and Physiology of Electrical Stimulation of the Central Nervous System; Warren M. Grill

Transcutaneous FES for Ambulation: The Parastep System; Daniel Graupe

Comparing Electrodes for Use as Cortical Control Signals: Tines, Wires, or Cones on Wires—Which Is Best?; Philip R. Kennedy

Development of a Multifunctional 22-Channel Functional Electrical Stimulator for Paraplegia; R. Davis, T. Johnston, B. Smith, R. Betz, T. Houdayer, and A. Barriskill

An Implantable Bionic Network of Injectable Neural Prosthetic Devices: The Future Platform for Functional Electrical Stimulation and Sensing to Restore Movement and Sensation; J. Schulman, P. Mobley, J. Wolfe, R. Davis, and I. Arcos

Visual Prostheses; Robert J. Greenberg

Interfering with the Genesis and Propagation of Epileptic Seizures by Neuromodulation; Ana Luisa Velasco, Francisco Velasco, Marcos Velasco, Bernardo Boleaga, Mauricio Kuri, Fiacro Jiménez, and José María Núñez

Transcranial Magnetic Stimulation of Deep Brain Regions; Yiftach Roth and Abraham Zangen

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Joseph D. Bronzino is the founder and president of the Biomedical Engineering Alliance and Consortium (BEACON) in Hartford, Connecticut. He earned a PhD in electrical engineering from Worcester Polytechnic Institute in Massachusetts. Dr. Bronzino has received the Millennium Award from IEEE/EMBS and the Goddard Award from Worcester Polytechnic Institute for Professional Achievement. He is the author of more than 200 articles and 11 books.

Donald R. Peterson is a professor of engineering and dean of the College of Science, Technology, Engineering, Mathematics, and Nursing at Texas A&M University–Texarkana. He earned a PhD in biomedical engineering from Worcester Polytechnic Institute in Massachusetts. Dr. Peterson’s recent research focuses on measuring and modeling human, organ, and/or cell performance, including exposures to various physical stimuli and the subsequent biological responses. Dr. Peterson has published more than 50 journal articles and 12 reference books.