2nd Edition

Biomedical Engineering Fundamentals

    1180 Pages
    by CRC Press

    1180 Pages 645 B/W Illustrations
    by CRC Press

    Known as the bible of biomedical engineering, The Biomedical Engineering Handbook, Fourth Edition, sets the standard against which all other references of this nature are measured. As such, it has served as a major resource for both skilled professionals and novices to biomedical engineering.

    Biomedical Engineering Fundamentals, the first volume of the handbook, presents material from respected scientists with diverse backgrounds in physiological systems, biomechanics, biomaterials, bioelectric phenomena, and neuroengineering.

    More than three dozen specific topics are examined, including cardiac biomechanics, the mechanics of blood vessels, cochlear mechanics, biodegradable biomaterials, soft tissue replacements, cellular biomechanics, neural engineering, electrical stimulation for paraplegia, and visual prostheses. The material is presented in a systematic manner and has been updated to reflect the latest applications and research findings.


    An Outline of Cardiovascular Structure and Function; Daniel J. Schneck

    Kidney Structure and Physiology; Joel M. Henderson and Mostafa Belghasem

    Nervous System; Evangelia Micheli-Tzanakou

    Vision System; Aaron P. Batista and George D. Stetten

    Auditory System; Ben M. Clopton and Herbert F. Voigt

    Gastrointestinal System; Berj L. Bardakjian

    Respiratory System; Arthur T. Johnson, Christopher G. Lausted, and Joseph D. Bronzino


    Mechanics of Hard Tissue; J. Lawrence Katz, Anil Misra, Orestes Marangos, Qiang Ye, and Paulette Spencer

    Musculoskeletal Soft-Tissue Mechanics; Richard L. Lieber, Samuel R. Ward, and Thomas J. Burkholder

    Joint-Articulating Surface Motion; Kenton R. Kaufman and Kai-Nan An

    Joint Lubrication; Michael J. Furey

    Analysis of Gait; Roy B. Davis, III, Sylvia Õunpuu, and Peter A. DeLuca

    Mechanics of Head/Neck; Albert I. King and David C. Viano

    Biomechanics of Chest and Abdomen Impact; David C. Viano and Albert I. King

    Cardiac Biomechanics; Andrew D. McCulloch and Roy C.P. Kerckhoffs

    Heart Valve Dynamics; Choon Hwai Yap, Erin Spinner, Muralidhar Padala, and Ajit P. Yoganathan

    Arterial Macrocirculatory Hemodynamics; Baruch B. Liber

    Mechanics of Blood Vessels; Thomas R. Canfield and Philip B. Dobrin

    The Venous System; Artin A. Shoukas and Carl F. Rothe

    The Microcirculation Physiome; Aleksander S. Popel and Roland N. Pittman

    Mechanics and Deformability of Hematocytes; Richard E. Waugh and Robert M. Hochmuth

    Mechanics of Tissue/Lymphatic Transport; Geert W. Schmid-Schönbein and Alan R. Hargens

    Modeling in Cellular Biomechanics; Alexander A. Spector and Roger Tran-Son-Tay

    Cochlear Mechanics; Charles R. Steele and Sunil Puria

    Inner Ear Hair Cell Bundle Mechanics; Jong-Hoon Nam and Wally Grant

    Exercise Physiology; Cathryn R. Dooly and Arthur T. Johnson

    Factors Affecting Mechanical Work in Humans; Ben F. Hurley and Arthur T. Johnson


    Metallic Biomaterials; Joon B. Park and Young Kon Kim

    Ceramic Biomaterials; W.G. Billotte

    Polymeric Biomaterials; Hai Bang Lee, Gilson Khang, and Jin Ho Lee

    Composite Biomaterials; Roderic S. Lakes

    Biodegradable Polymeric Biomaterials: An Updated Overview; C.C. Chu

    Biologic Biomaterials: Tissue-Derived Biomaterials (Collagen); Shu-Tung Li

    Biologic Biomaterials: Silk; Biman Mandal and David L. Kaplan

    Biofunctional Hydrogels; Melissa K. McHale and Jennifer L. West

    Soft Tissue Replacements; K.B. Chandran, K.J.L. Burg, and S.W. Shalaby

    Hard Tissue Replacements; Sang-Hyun Park, Adolfo Llinás, and Vijay K. Goel


    Basic Electrophysiology; Roger C. Barr

    Volume Conductor Theory; Robert Plonsey

    Electrical Conductivity of Tissues; Bradley J. Roth

    Cardiac Microimpedances; Andrew E. Pollard

    Membrane Models; Anthony Varghese

    Computational Methods and Software for Bioelectric Field Problems; Christopher R. Johnson

    The Potential Fields of Triangular Boundary Elements; A. van Oosterom

    Principles of Electrocardiography; Edward J. Berbari

    Electrodiagnostic Studies; Sanjeev D. Nandedkar

    Principles of Electroencephalography; Joseph D. Bronzino

    Biomagnetism; Jaakko Malmivuo

    Electrical Stimulation of Excitable Tissue; Dominique M. Durand


    History and Overview of Neural Engineering; Daniel DiLorenzo and Robert E. Gross

    Theory and Physiology of Electrical Stimulation of the Central Nervous System; Warren M. Grill

    Transcutaneous FES for Ambulation: The Parastep System; Daniel Graupe

    Comparing Electrodes for Use as Cortical Control Signals: Tines, Wires, or Cones on Wires—Which Is Best?; Philip R. Kennedy

    Development of a Multifunctional 22-Channel Functional Electrical Stimulator for Paraplegia; R. Davis, T. Johnston, B. Smith, R. Betz, T. Houdayer, and A. Barriskill

    An Implantable Bionic Network of Injectable Neural Prosthetic Devices: The Future Platform for Functional Electrical Stimulation and Sensing to Restore Movement and Sensation; J. Schulman, P. Mobley, J. Wolfe, R. Davis, and I. Arcos

    Visual Prostheses; Robert J. Greenberg

    Interfering with the Genesis and Propagation of Epileptic Seizures by Neuromodulation; Ana Luisa Velasco, Francisco Velasco, Marcos Velasco, Bernardo Boleaga, Mauricio Kuri, Fiacro Jiménez, and José María Núñez

    Transcranial Magnetic Stimulation of Deep Brain Regions; Yiftach Roth and Abraham Zangen


    Joseph D. Bronzino is the founder and president of the Biomedical Engineering Alliance and Consortium (BEACON) in Hartford, Connecticut. He earned a PhD in electrical engineering from Worcester Polytechnic Institute in Massachusetts. Dr. Bronzino has received the Millennium Award from IEEE/EMBS and the Goddard Award from Worcester Polytechnic Institute for Professional Achievement. He is the author of more than 200 articles and 11 books.

    Donald R. Peterson is a professor of engineering and dean of the College of Science, Technology, Engineering, Mathematics, and Nursing at Texas A&M University–Texarkana. He earned a PhD in biomedical engineering from Worcester Polytechnic Institute in Massachusetts. Dr. Peterson’s recent research focuses on measuring and modeling human, organ, and/or cell performance, including exposures to various physical stimuli and the subsequent biological responses. Dr. Peterson has published more than 50 journal articles and 12 reference books.