Biomedical Nanosensors: 1st Edition (Hardback) book cover

Biomedical Nanosensors

1st Edition

Edited by Joseph M. Irudayaraj

Jenny Stanford Publishing

398 pages | 32 Color Illus. | 98 B/W Illus.

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Hardback: 9789814303033
pub: 2012-11-21
eBook (VitalSource) : 9780429113185
pub: 2012-11-21
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This book draws together recent data on both cytoplasmic and flagellar dyneins and the proteins they interact with, to give the reader a clear picture of what is currently known about the structure and mechanics of these remarkable macro-molecular machines. Each chapter is written by active researchers, with a focus on currently used biophysical, biochemical, and cell biological methods. In addition to comprehensive coverage of structural information gained by electron microscopy, electron cryo-tomography, X-ray crystallography, and nuclear magnetic resonance, this book provides detailed descriptions of mechanistic experiments by single-molecule nanometry.


"Biomedical nanosensors have a wide range of applications in human, animal, and plant health for diagnostics and therapeutics. Assembled by Prof. Joseph Irudayaraj, this book is an important reference in the exciting, important, and rapidly evolving field of biomedical nanotechnology. The chapters are detailed and thorough, and rich with references. It is an interdisciplinary collection of contributions from experts with diverse backgrounds, and therefore a very interesting and educational read for students and faculty researchers in bionanotechnology."

—Prof. Rashid Bashir - University of Illinois at Urbana-Champaign, USA

"This book gives an inspirational overview on current developments in nanomaterial and nanoarchitecture for advanced sensing applications in the fields of medical diagnostics and therapeutics agents for drug delivery. It focuses on the nanoscale perspective of materials properties towards new sensing strategies to study the biological systems with improved sensitivity, to characterize molecular interaction and cellular mechanisms at molecular or cellular dimension. The content is comprehensive and rich in references covering the topics on fundamental biosensor design, natural and synthetic biorecognition elements, inorganic nanomaterials such as gold nanoparticles and carbon nanotube-based sensors, engineered nanoparticles for drug delivery, and nanoarchitecture and nanodevices towards implantable sensing. Each chapter is provided with a clear and brief introduction, the sub-topics are well organized and easy to follow, and summarized with a prospective and future outlook. . . .

I am very impressed by the concise and informative content of this . . . very useful reference work for research scientists working in the field of nanotechnology, as well as high school teachers and university students to get an overview on the topic of biomedical nanosensors."

—Dr. W. C. Mak, Biosensors and Bioelectronics Centre, Department of Physics, Chemistry and Biology, Linköping University, Sweden

Table of Contents

Biomolecular Components of a Biosensor: Fundamentals, Kaustubh D. Bhalerao and Goutam J. Nistala

What Makes a Biosensor a Biosensor?

The Recognition Layer


Conclusions and Future Outlook

Macromolecule-Imprinted Polymers: Antibody/Receptor Mimics for Protein Recognition and Catalysis, Yun Peng, David W. Britt, Marie K. Walsh, and Timothy Doyle




Chemical and Biological Sensing and Imaging Using Plasmonic Nanoparticles and Nanostructures, Qi Wang and Chenxu Yu


Theoretical Background of nanoSPR

Synthesis, Fabrication, and Functionalization of Plasmonic Nanostructures

Application of nanoSPR in Chemical and Biological Sensing

Conclusions and Future Perspectives

Surface-Raman Scattering for Medical Applications, Mustafa Çulha


Introduction to Raman Scattering and Surface-Enhanced Raman Scattering

Applications of SERS in Biomedical Sciences and Medicine

Concluding Remarks and Future Outlook

Diagnostic and Therapeutic Applications of Carbon Nanotubes, Balaji Panchapakesan, Thomas Burkhead, Ben King, Peng Xu, James Loomis, and Eric Wickstrom


Nanotechnology for Cancer

Carbon Nanotubes

Electronic Properties of Carbon Nanotubes

Optical Properties of Carbon Nanotubes

Biological Applications of Carbon Nanotubes

Bioelectronic Devices Based on Carbon Nanotubes

Applications of Nanotube Transistors for Detecting Circulating Cancer Cells

Integrated Molecular Targeting and Selective Photothermal Therapy of Breast Cancer Cells Using Carbon Nanotubes

Conclusions and Future Applications of Carbon Nanotubes for Biomedical

Graphene for Biosensing Applications, Romaneh Jalilian, Luis A. Jauregui, Kyuwan Lee, Yong P. Chen, and Joseph Irudayaraj


Fabrication of Graphene-Based Materials and Devices

Basic Properties of Graphene

Biosensing Applications of Graphene

Closing Remarks and Future Work

Single-Molecule Fluorescence Spectroscopy Techniques for Biomedicine, Jose M. Moran-Mirabal, Harold G. Craighead, and Larry P. Walker

Single-Molecule Fluorescence Spectroscopy Fundamentals

Experimental Implementations of SMFS Techniques

Observables Measured with SMFS Techniques

Micro- and Nanostructured Surfaces for SMFS

Micro- and Nanofluidic Slits and Channels

Potential Biomedical SMFS Applications

Particle Engineering for Inhalational Drug Delivery, Basma Ibrahim, Yan Yang, and Yoon Yeo

Dry Particles for Inhalational Therapy

Traditional Particle Manufacturing for Inhalational Drug Delivery

NPs for Inhalational Drug Delivery


Devices and Sensors for Bioelectric Monitoringand Stimulation, Benjamin Moody, Mathew K. Zachek, and Gregory S. McCarty


Electrode Basics

Electrochemical Measurements

Biosensor Electrodes

Advances in Electrodes for Biological Measurements

Applications in the Brain

Applications to the Heart and Muscles


Microelectromechanical Systems for in vivo Therapeutics, Masaru P. Rao


Advantageous Features of MEMS

The MEMS "Tool Kit": Common MEMS Materials and Fabrication Techniques

Selected Examples of Application Areas within in vivo Therapeutics

In vivo Therapeutic MEMS Enabled by Titanium Micromachining

Conclusions and Outlook

Implantable Electrochemical Biosensors: A Perspective, Sridhar Govindarajan and Bella B. Manshian


In vivo Monitoring — Challenges and Progress



About the Series

Pan Stanford Series on Biomedical Nanotechnology

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Subject Categories

BISAC Subject Codes/Headings:
SCIENCE / Chemistry / Industrial & Technical