2nd Edition

Biomedical Photonics Handbook, 3 Volume Set

Edited By Tuan Vo-Dinh
    827 B/W Illustrations
    by CRC Press

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    Shaped by Quantum Theory, Technology, and the Genomics Revolution

    The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers.

    Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians

    Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies.

    What’s New in This Edition:

    A wide variety of photonic biochemical sensing technologies have already been developed for clinical monitoring of physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics and metabolomics allow sensing of early disease state biomarkers, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules and in situ diagnostics at the single cell level. In addition to these state-of-the art advancements, the second edition contains new topics and chapters including:

    • Fiber Optic Probe Design
    • Laser and Optical Radiation Safety
    • Photothermal Detection
    • Multidimensional Fluorescence Imaging
    • Surface Plasmon Resonance Imaging
    • Molecular Contrast Optical Coherence Tomography
    • Multiscale Photoacoustics
    • Polarized Light for Medical Diagnostics
    • Quantitative Diffuse Reflectance Imaging
    • Interferometric Light Scattering
    • Nonlinear Interferometric Vibrational Imaging
    • Multimodality Theranostics Nanoplatforms
    • Nanoscintillator-Based Therapy
    • SERS Molecular Sentinel Nanoprobes
    • Plasmonic Coupling Interference Nanoprobes

    Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and lists of references for further reading.

    Volume One:

    Photonics and Tissue Optics

    Optical Properties of Tissues; Joel Mobley, Tuan Vo-Dinh and Valery Tuchin

    Light-Tissue Interactions; Valery V. Tuchin

    Theoretical Models and Algorithms in Optical Diffusion Tomography; Stephen J. Norton and Tuan Vo-Dinh

    Basic Instrumentation

    Basic Instrumentation in Photonics; Tuan Vo-Dinh

    Optical Fibers and Waveguides for Medical Applications; Israel Gannot and Moshe Ben David

    Fiberoptics Probe Design; Urs Utzinger

    Laser and Optical Radiation Safety in Biophotonics; Robert J. Landry, T. Joshua Pfefer, and Ilko K. Ilev

    Photonic Detection and Imaging Techniques

    Biological Imaging Spectroscopy; Gregory Bearman, David Cuccia and Richard Levenson

    Lifetime-Based Imaging; Petr Herman and Joseph R. Lakowicz

    Confocal Microscopy; Tony Wilson

    Two-Photon Excitation Fluorescence Microscopy; Peter T.C. So, Chen Y. Dong, and Barry R. Masters

    Laser Doppler Perfusion Monitoring and Imaging; T. Stromberg and K. Wardell, M. Larsson, and E.G. Salerud

    Light Scatter Spectroscopy and Imaging of Cellular and Subcellular Events; Nada N. Boustany and Nitish V. Thakor

    Tissue Viability Imaging; Gert E. Nilsson

    Photothermal Detection and Tracking of Individual Non-fluorescent Nanosystems; Laurent Cognet & Brahim Lounis

    Thermal Imaging; Jay Gore and Lisa X. Xu

    Multidimensional fluorescence imaging of biological tissue; Paul French

    Speckle Correlometry; Dmitry A. Zimnyakov and Valery V. Tuchi

    Spectroscopic Data

    Spectroscopic Data in Biological and Biomedical Analysis; Dimitra N. Stratis-Cullum, Mikella E. Farrell, Ellen Holthoff, David L. Stokes,Brian M. Cullum, Joon Myong Song, Paul M. Kasili, Ramesh Jaganathan, and Tuan Vo-Dinh

    Volume Two:

    Biomedical Analysis, Sensing and Imaging

    Biosensors for Medical Applications; Tuan Vo-Dinh, Leonardo Allain and Andrew Fales

    Glucose Monitoring; Casey W. Pirnstill, Brian Cummins, Gerard L. Coté, Roger J. McNichols

    Biochips and MicroArrays: Tools for the New Medicine; Tuan Vo-Dinh and G. D. Griffin

    Atomic Spectroscopy for Biological and Clinical Analysis; Andrew Taylor

    Flow Cytometry; Francis Mandy, Joe Trotter, Rudi Varro, Ming Yan, and Diether Recktenwald

    Capillary Electrophoresis Techniques in Biomedical Analysis; S. Douglas Gilman and Michael J. Sepaniak

    Surface Plasmon Resonance Imaging: Principle, Development, and Biomedical Applications; Julien Moreau, Jean-Pierre Cloarec, Paul Charette, Michel Goossens, Michael Canva, Tuan Vo-Dinh

    Surface-Enhanced Raman Scattering (SERS) for Biomedical Diagnostics; Tuan Vo-Dinh and David L. Stokes

    Functional Imaging with Diffusing Light; Arjun G. Yodh and David A. Boas

    Molecular Contrast Optical Coherence Tomography; Oscar Carrasco-Zevallos, and Joseph Izatt

    Multiscale Photoacoustic Microscopy and Macroscopy; Song Hu and Lihong V. Wang

    Polarized light for Medical Diagnostics; Steven L. Jacques

    X-Ray Diagnostic Techniques; Xizeng Wu, Molly. D. Wong, Abby E. Deans and Hong Liu

    Optical Pumping and MRI of Hyperpolarized Spins; Xizeng Wu, Thomas Nishino and Hong Liu

    Biomedical Diagnostics and Optical Biopsy

    Fluorescence Spectroscopy for Biomedical Diagnostics; Tuan Vo-Dinh and Brian M. Cullum

    Elastic-Scattering Spectroscopy and Diffuse Reflectance; Judith R. Mourant and Irving J. Bigio

    Quantitative Diffuse Reflectance Imaging of Tumor Margins; Bing Yu, Nirmala Ramanujam

    Near Infrared Fluorescence Imaging and Spectroscopy in Random Media and Tissues; E.M. Sevick-Muraka, E. Kuwana, A. Godavarty, J.P. Houston, A.B. Thompson, R.Roy

    Interferometric Light Scattering Techniques For Measuring Nuclear Morphology and Detecting Dysplasia; Yizheng Zhu, Francisco E. Robles, Neil G. Terry, and Adam Wax

    Ultrasonically Modulated Optical Imaging; François Ramaz, Emmanuel Bossy, Michel Gross and A. Claude Boccara

    Optoacoustic Tomography; Alexander A. Oraevsky and Alexander A. Karabutov

    Raman Spectroscopy: From Benchtop to Bedside; Anita Mahadevan-Jansen

    Fourier Transform Infrared (FTIR) Microspectroscopic Methods for Biomedical Analyses: From Single Point Detection to Two-Dimensional Imagin; Rohit Bhargava and Ira W. Levin

    Photon Migration Spectroscopy Frequency-Domain Techniques; Albert E. Cerussi and Bruce J. Tromberg

    Volume Three:

    Therapeutic and Interventional Techniques

    Mechanistic Principles of Photodynamic Therapy; Barbara W Henderson Sandra O Gollnick

    Synthesis and Biological Significance of Porphyrin-based Photosensitizers in Photodynamic Therapy; Penny Joshi Ravindra K Pandey

    Lasers in Dermatology; Lilit Garibyan H Ray Jalian Kittisak Suthamjariya and R Rox Anderson

    Lasers in Interventional Pulmonolog; Anubhav N Mathur Praveen N Mathur

    Lasers in Diagnostics and Treatment of Brain Disease; Steen J Madsen Bernard Choi Henry Hirschberg

    Lasers in Ophthalmology; Ezra Maguen Thomas G Chu and David Boyer

    Lasers in Otolaryngology; Lou Reinisch

    Therapeutic Applications of Lasers in Gastroenterology; Masoud Panjehpour Bergein F Overholt

    Low-Power Laser Therapy; Tina I Karu

    Image Guided Surgery; Richard D Bucholz Keith A Laycock

    Optical Methods for Caries Detection Diagnosis and Therapeutic Intervention; Daniel Fried

    Nonlinear Interferometric Vibrational Imaging and Spectroscopy; Haohua Tu Zhi Jiang Praveen D Chowdary Wladimir Benalcazar Eric J Chaney Daniel L Marks Martin Gruebele Stephen A Boppart

    Multifunctional Theranostic Platform: Plasmonic-Active Gold Nanostars; Hsiangkuo Yuan, Andrew M Fales, Tuan Vo-Dinh

    Activity Of Psoralen-Functionalized Nanoscintillators Against Cancer Cells Upon X-Ray Excitation; John Scaffidi Molly K Gregas Bernard Lauly Yang Zhang Tuan Vo-Dinh

    Advanced Biophotonics and Nanophotonics

    Living Cell Analysis Using Optical Methods; Pierre M Viallet Tuan Vo-Dinh

    Amplification Techniques for Optical Detection; Guy D Griffin Dimitra N Stratis-Cullum Timothy E McKnight M Wendy Williams Tuan Vo-Dinh

    Fluorescent Probes in Biomedical Application; Darryl J Bornhop Kai Licha and Lynn E Samuelson

    Optical Trapping Techniques in Bioanalysis; Kenji Yasuda

    Luminescent Nanoparticle-Based Probes for Bioassays; Georgeta Crivat Sandra M Da Silva Ashley D Quach Venkata R Kethineedi Matthew A Tarr and Zeev Rosenzweig

    Fluorescent Molecular Beacon Nucleic Acid Probes for Biomolecular Recognition; Cuichen Wu Chaoyong James Yang Kemin Wang Xiaohong Fang Terry Beck Richard Hogrefe Weihong Tan

    Luminescent Quantum Dots for Diagnositc and Bioimaging Applications; Brad A Kairdolf Shuming Nie

    PEBBLE Nanosensors for In Vitro Bioanalysis; Yong-Eun Koo Lee Eric Monson Murphy Brasuel Martin A Philbert Raoul Kopelman

    Nanosensors for Single-Cell Analyses; Charles K Klutse Brian M Cullum, Molly K Gregas, John P Scaffidi, Tuan Vo-Dinh

    SERS Molecular Sentinel Nanoprobes to Detect Biomarkers for Medical Diagnostics; Tuan Vo-Dinh Hsin-Neng Wang Hoan Thanh Ngo

    Plasmonic Coupling Interference (PCI) Nanoprobes for Gene Diagnostics; Hsin-Neng Wang Stephen Norton Tuan Vo-Dinh

    DNA Sequencing using Fluorescence Detection; Steven A Soper, Clyde V Owens, Suzanne J Lassiter, Yichuan Xu and Emanuel Waddell

    In Vivo Bioluminescence Imaging as a Tool for Drug Development; Pamela R Contag Christopher H Contag






    Tuan Vo-Dinh

    "Excellent book! Sheds new, latest and important light on the field of biomedical photonics. The second edition has put together a comprehensive resource covering all aspects of photonics in the field of biomedicine under three volumes. The use of practical examples summarizing real-world examples by scientists and engineers allows a collective look into the current best practices. This book will be valuable to anyone seeking to understand the complexities of designing fiber optic instruments, techniques involved behind analysis, diagnostics nuances and therapeutic modalities. Students and practitioners will learn about the latest tools and techniques used by leading researchers, scientists and engineers. A great compilation of varied research fields in the area of Biophotonics. Especially, a great reference book as topics are effectively dealt in-depth with lots of citations after each chapter."
    —Dr. Shanthi Prince, SRM University, India

    "No one has, or ever will, attempt to create such a comprehensive text in this field. It is an enormous undertaking that we are all grateful to have, but would not want to do it ourselves."
    —Christopher H. Contag, Stanford University, California, USA

    "… extensive and comprehensive coverage, resulting in an additional two volumes of material in this new edition … [containing] the latest research and technology in biomedical optics/photonics."
    —Inci Cilesiz, Istanbul Technical University, Turkey

    "I like the breadth of topics, particularly the fact that they cover fundamental issues as well as advanced research areas. … exhaustive coverage of biomedical optics starting from the very basic fundamentals to a wide variety of cutting-edge concepts. This makes the text ideal for all levels of readers—from undergraduate students to senior researchers."
    —Kartikeya Murari, University of Calgary, Alberta, Canada

    "… written in a clear language providing an easy transaction from the basic and fundamental concepts to expert level topics. This approach makes these materials very suitable for academic purposes. … an excellent reference book for the researcher, teacher, and student. It provides a detailed and up-to-date expert coverage of fundamental concepts and current biomedical photonics techniques and applications. It also addresses several frontier research topics and emergent technologies that will surely result in future applications."
    —António Miguel Morgado, University of Coimbra, Portugal

    "This handbook is a step ahead in the sense that it brings together the recent advances in various fields of biomedical photonics. [It] serves as a teaching reference as well as a research guide."
    —Renu John, Indian Institute of Technology Hyderabad, Telangana