Biomedical Photonics Handbook, 3 Volume Set  book cover
2nd Edition

Biomedical Photonics Handbook, 3 Volume Set

Edited By

Tuan Vo-Dinh

ISBN 9781439804445
Published July 29, 2014 by CRC Press
827 B/W Illustrations

FREE Standard Shipping
SAVE $75.00
was $375.00
USD $300.00

Prices & shipping based on shipping country


Book Description

Shaped by Quantum Theory, Technology, and the Genomics Revolution

The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers.

Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians

Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies.

What’s New in This Edition:

A wide variety of photonic biochemical sensing technologies have already been developed for clinical monitoring of physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics and metabolomics allow sensing of early disease state biomarkers, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of disease, imaging single molecules and in situ diagnostics at the single cell level. In addition to these state-of-the art advancements, the second edition contains new topics and chapters including:

  • Fiber Optic Probe Design
  • Laser and Optical Radiation Safety
  • Photothermal Detection
  • Multidimensional Fluorescence Imaging
  • Surface Plasmon Resonance Imaging
  • Molecular Contrast Optical Coherence Tomography
  • Multiscale Photoacoustics
  • Polarized Light for Medical Diagnostics
  • Quantitative Diffuse Reflectance Imaging
  • Interferometric Light Scattering
  • Nonlinear Interferometric Vibrational Imaging
  • Multimodality Theranostics Nanoplatforms
  • Nanoscintillator-Based Therapy
  • SERS Molecular Sentinel Nanoprobes
  • Plasmonic Coupling Interference Nanoprobes

Comprised of three books: Volume I: Fundamentals, Devices, and Techniques; Volume II: Biomedical Diagnostics; and Volume III: Therapeutics and Advanced Biophotonics, this second edition contains eight sections, and provides introductory material in each chapter. It also includes an overview of the topic, an extensive collection of spectroscopic data, and lists of references for further reading.

Table of Contents

Volume One:

Photonics and Tissue Optics

Optical Properties of Tissues; Joel Mobley, Tuan Vo-Dinh and Valery Tuchin

Light-Tissue Interactions; Valery V. Tuchin

Theoretical Models and Algorithms in Optical Diffusion Tomography; Stephen J. Norton and Tuan Vo-Dinh

Basic Instrumentation

Basic Instrumentation in Photonics; Tuan Vo-Dinh

Optical Fibers and Waveguides for Medical Applications; Israel Gannot and Moshe Ben David

Fiberoptics Probe Design; Urs Utzinger

Laser and Optical Radiation Safety in Biophotonics; Robert J. Landry, T. Joshua Pfefer, and Ilko K. Ilev

Photonic Detection and Imaging Techniques

Biological Imaging Spectroscopy; Gregory Bearman, David Cuccia and Richard Levenson

Lifetime-Based Imaging; Petr Herman and Joseph R. Lakowicz

Confocal Microscopy; Tony Wilson

Two-Photon Excitation Fluorescence Microscopy; Peter T.C. So, Chen Y. Dong, and Barry R. Masters

Laser Doppler Perfusion Monitoring and Imaging; T. Stromberg and K. Wardell, M. Larsson, and E.G. Salerud

Light Scatter Spectroscopy and Imaging of Cellular and Subcellular Events; Nada N. Boustany and Nitish V. Thakor

Tissue Viability Imaging; Gert E. Nilsson

Photothermal Detection and Tracking of Individual Non-fluorescent Nanosystems; Laurent Cognet & Brahim Lounis

Thermal Imaging; Jay Gore and Lisa X. Xu

Multidimensional fluorescence imaging of biological tissue; Paul French

Speckle Correlometry; Dmitry A. Zimnyakov and Valery V. Tuchi

Spectroscopic Data

Spectroscopic Data in Biological and Biomedical Analysis; Dimitra N. Stratis-Cullum, Mikella E. Farrell, Ellen Holthoff, David L. Stokes,Brian M. Cullum, Joon Myong Song, Paul M. Kasili, Ramesh Jaganathan, and Tuan Vo-Dinh

Volume Two:

Biomedical Analysis, Sensing and Imaging

Biosensors for Medical Applications; Tuan Vo-Dinh, Leonardo Allain and Andrew Fales

Glucose Monitoring; Casey W. Pirnstill, Brian Cummins, Gerard L. Coté, Roger J. McNichols

Biochips and MicroArrays: Tools for the New Medicine; Tuan Vo-Dinh and G. D. Griffin

Atomic Spectroscopy for Biological and Clinical Analysis; Andrew Taylor

Flow Cytometry; Francis Mandy, Joe Trotter, Rudi Varro, Ming Yan, and Diether Recktenwald

Capillary Electrophoresis Techniques in Biomedical Analysis; S. Douglas Gilman and Michael J. Sepaniak

Surface Plasmon Resonance Imaging: Principle, Development, and Biomedical Applications; Julien Moreau, Jean-Pierre Cloarec, Paul Charette, Michel Goossens, Michael Canva, Tuan Vo-Dinh

Surface-Enhanced Raman Scattering (SERS) for Biomedical Diagnostics; Tuan Vo-Dinh and David L. Stokes

Functional Imaging with Diffusing Light; Arjun G. Yodh and David A. Boas

Molecular Contrast Optical Coherence Tomography; Oscar Carrasco-Zevallos, and Joseph Izatt

Multiscale Photoacoustic Microscopy and Macroscopy; Song Hu and Lihong V. Wang

Polarized light for Medical Diagnostics; Steven L. Jacques

X-Ray Diagnostic Techniques; Xizeng Wu, Molly. D. Wong, Abby E. Deans and Hong Liu

Optical Pumping and MRI of Hyperpolarized Spins; Xizeng Wu, Thomas Nishino and Hong Liu

Biomedical Diagnostics and Optical Biopsy

Fluorescence Spectroscopy for Biomedical Diagnostics; Tuan Vo-Dinh and Brian M. Cullum

Elastic-Scattering Spectroscopy and Diffuse Reflectance; Judith R. Mourant and Irving J. Bigio

Quantitative Diffuse Reflectance Imaging of Tumor Margins; Bing Yu, Nirmala Ramanujam

Near Infrared Fluorescence Imaging and Spectroscopy in Random Media and Tissues; E.M. Sevick-Muraka, E. Kuwana, A. Godavarty, J.P. Houston, A.B. Thompson, R.Roy

Interferometric Light Scattering Techniques For Measuring Nuclear Morphology and Detecting Dysplasia; Yizheng Zhu, Francisco E. Robles, Neil G. Terry, and Adam Wax

Ultrasonically Modulated Optical Imaging; François Ramaz, Emmanuel Bossy, Michel Gross and A. Claude Boccara

Optoacoustic Tomography; Alexander A. Oraevsky and Alexander A. Karabutov

Raman Spectroscopy: From Benchtop to Bedside; Anita Mahadevan-Jansen

Fourier Transform Infrared (FTIR) Microspectroscopic Methods for Biomedical Analyses: From Single Point Detection to Two-Dimensional Imagin; Rohit Bhargava and Ira W. Levin

Photon Migration Spectroscopy Frequency-Domain Techniques; Albert E. Cerussi and Bruce J. Tromberg

Volume Three:

Therapeutic and Interventional Techniques

Mechanistic Principles of Photodynamic Therapy; Barbara W Henderson Sandra O Gollnick

Synthesis and Biological Significance of Porphyrin-based Photosensitizers in Photodynamic Therapy; Penny Joshi Ravindra K Pandey

Lasers in Dermatology; Lilit Garibyan H Ray Jalian Kittisak Suthamjariya and R Rox Anderson

Lasers in Interventional Pulmonolog; Anubhav N Mathur Praveen N Mathur

Lasers in Diagnostics and Treatment of Brain Disease; Steen J Madsen Bernard Choi Henry Hirschberg

Lasers in Ophthalmology; Ezra Maguen Thomas G Chu and David Boyer

Lasers in Otolaryngology; Lou Reinisch

Therapeutic Applications of Lasers in Gastroenterology; Masoud Panjehpour Bergein F Overholt

Low-Power Laser Therapy; Tina I Karu

Image Guided Surgery; Richard D Bucholz Keith A Laycock

Optical Methods for Caries Detection Diagnosis and Therapeutic Intervention; Daniel Fried

Nonlinear Interferometric Vibrational Imaging and Spectroscopy; Haohua Tu Zhi Jiang Praveen D Chowdary Wladimir Benalcazar Eric J Chaney Daniel L Marks Martin Gruebele Stephen A Boppart

Multifunctional Theranostic Platform: Plasmonic-Active Gold Nanostars; Hsiangkuo Yuan, Andrew M Fales, Tuan Vo-Dinh

Activity Of Psoralen-Functionalized Nanoscintillators Against Cancer Cells Upon X-Ray Excitation; John Scaffidi Molly K Gregas Bernard Lauly Yang Zhang Tuan Vo-Dinh

Advanced Biophotonics and Nanophotonics

Living Cell Analysis Using Optical Methods; Pierre M Viallet Tuan Vo-Dinh

Amplification Techniques for Optical Detection; Guy D Griffin Dimitra N Stratis-Cullum Timothy E McKnight M Wendy Williams Tuan Vo-Dinh

Fluorescent Probes in Biomedical Application; Darryl J Bornhop Kai Licha and Lynn E Samuelson

Optical Trapping Techniques in Bioanalysis; Kenji Yasuda

Luminescent Nanoparticle-Based Probes for Bioassays; Georgeta Crivat Sandra M Da Silva Ashley D Quach Venkata R Kethineedi Matthew A Tarr and Zeev Rosenzweig

Fluorescent Molecular Beacon Nucleic Acid Probes for Biomolecular Recognition; Cuichen Wu Chaoyong James Yang Kemin Wang Xiaohong Fang Terry Beck Richard Hogrefe Weihong Tan

Luminescent Quantum Dots for Diagnositc and Bioimaging Applications; Brad A Kairdolf Shuming Nie

PEBBLE Nanosensors for In Vitro Bioanalysis; Yong-Eun Koo Lee Eric Monson Murphy Brasuel Martin A Philbert Raoul Kopelman

Nanosensors for Single-Cell Analyses; Charles K Klutse Brian M Cullum, Molly K Gregas, John P Scaffidi, Tuan Vo-Dinh

SERS Molecular Sentinel Nanoprobes to Detect Biomarkers for Medical Diagnostics; Tuan Vo-Dinh Hsin-Neng Wang Hoan Thanh Ngo

Plasmonic Coupling Interference (PCI) Nanoprobes for Gene Diagnostics; Hsin-Neng Wang Stephen Norton Tuan Vo-Dinh

DNA Sequencing using Fluorescence Detection; Steven A Soper, Clyde V Owens, Suzanne J Lassiter, Yichuan Xu and Emanuel Waddell

In Vivo Bioluminescence Imaging as a Tool for Drug Development; Pamela R Contag Christopher H Contag





View More


"Excellent book! Sheds new, latest and important light on the field of biomedical photonics. The second edition has put together a comprehensive resource covering all aspects of photonics in the field of biomedicine under three volumes. The use of practical examples summarizing real-world examples by scientists and engineers allows a collective look into the current best practices. This book will be valuable to anyone seeking to understand the complexities of designing fiber optic instruments, techniques involved behind analysis, diagnostics nuances and therapeutic modalities. Students and practitioners will learn about the latest tools and techniques used by leading researchers, scientists and engineers. A great compilation of varied research fields in the area of Biophotonics. Especially, a great reference book as topics are effectively dealt in-depth with lots of citations after each chapter."
—Dr. Shanthi Prince, SRM University, India

"No one has, or ever will, attempt to create such a comprehensive text in this field. It is an enormous undertaking that we are all grateful to have, but would not want to do it ourselves."
—Christopher H. Contag, Stanford University, California, USA

"… extensive and comprehensive coverage, resulting in an additional two volumes of material in this new edition … [containing] the latest research and technology in biomedical optics/photonics."
—Inci Cilesiz, Istanbul Technical University, Turkey

"I like the breadth of topics, particularly the fact that they cover fundamental issues as well as advanced research areas. … exhaustive coverage of biomedical optics starting from the very basic fundamentals to a wide variety of cutting-edge concepts. This makes the text ideal for all levels of readers—from undergraduate students to senior researchers."
—Kartikeya Murari, University of Calgary, Alberta, Canada

"… written in a clear language providing an easy transaction from the basic and fundamental concepts to expert level topics. This approach makes these materials very suitable for academic purposes. … an excellent reference book for the researcher, teacher, and student. It provides a detailed and up-to-date expert coverage of fundamental concepts and current biomedical photonics techniques and applications. It also addresses several frontier research topics and emergent technologies that will surely result in future applications."
—António Miguel Morgado, University of Coimbra, Portugal

"This handbook is a step ahead in the sense that it brings together the recent advances in various fields of biomedical photonics. [It] serves as a teaching reference as well as a research guide."
—Renu John, Indian Institute of Technology Hyderabad, Telangana