Shaped by Quantum Theory, Technology, and the Genomics Revolution
The integration of photonics, electronics, biomaterials, and nanotechnology holds great promise for the future of medicine. This topic has recently experienced an explosive growth due to the noninvasive or minimally invasive nature and the cost-effectiveness of photonic modalities in medical diagnostics and therapy. The second edition of the Biomedical Photonics Handbook presents recent fundamental developments as well as important applications of biomedical photonics of interest to scientists, engineers, manufacturers, teachers, students, and clinical providers. The first volume, Fundamentals, Devices, and Techniques, focuses on the fundamentals of biophotonics, optical techniques, and devices.
Represents the Collective Work of over 150 Scientists, Engineers, and Clinicians
Designed to display the most recent advances in instrumentation and methods, as well as clinical applications in important areas of biomedical photonics to a broad audience, this three-volume handbook provides an inclusive forum that serves as an authoritative reference source for a broad audience involved in the research, teaching, learning, and practice of medical technologies.
What’s New in This Edition:
A wide variety of photonic biochemical sensing technologies has already been developed for clinical monitoring of physiological parameters, such as blood pressure, blood chemistry, pH, temperature, and the presence of pathological organisms or biochemical species of clinical importance. Advanced photonic detection technologies integrating the latest knowledge of genomics, proteomics, and metabolomics allow sensing of early disease states, thus revolutionizing the medicine of the future. Nanobiotechnology has opened new possibilities for detection of biomarkers of
Table of Contents
Photonics and Tissue Optics. Optical Properties of Tissues. Light-Tissue Interactions. Theoretical Models and Algorithms in Optical Diffusion Tomography. Basic Instrumentation. Basic Instrumentation in Photonics. Optical Fibers and Waveguides for Medical Applications. Fiberoptics Probe Design. Laser and Optical Radiation Safety in Biophotonics. Photonic Detection and Imaging Techniques. Biological Imaging Spectroscopy. Lifetime-Based Imaging. Confocal Microscopy. Two-Photon Excitation Fluorescence Microscopy. Laser Doppler Perfusion Monitoring and Imaging. Light Scatter Spectroscopy and Imaging of Cellular and Subcellular Events. Tissue Viability Imaging. Photothermal Detection and Tracking of Individual Non-fluorescent Nanosystems. Thermal Imaging. Multidimensional fluorescence imaging of biological tissue. Speckle Correlometry. Spectroscopic Data in Biological and Biomedical Analysis
Tuan Vo-Dinh is the R. Eugene and Susie E. Goodson Distinguished Professor of biomedical engineering, professor of chemistry, and director of the Fitzpatrick Institute for Photonics at Duke University. He received a B.S. in physics in 1970 from EPFL (Ecole Polytechnique Federal de Lausanne) in Lausanne and a Ph.D. in physical chemistry in 1975 from ETH (Swiss Federal Institute of Technology) in Zurich, Switzerland. Dr. Vo-Dinh has authored over 350 publications in peer-reviewed scientific journals. He is the author of a textbook on spectroscopy and editor of 6 books. He has received numerous awards and holds over 37 U.S. and international patents.