1st Edition

Biophysics of Gap Junction Channels

ISBN 9781315891194
Published November 29, 2017 by CRC Press
413 Pages

USD $290.00

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Book Description

This book provides a state of the art account of present knowledge of the biophysics of cell-to-cell channels. It is divided into two sections, one dealing with two-cell systems and the other with reconstitution systems.

Table of Contents

Section 1: Channels Studied in Two-Cell Systems 1. Channel Formation 2. Possible Involvement of Caffeine- and Ryanodine- Sensitive Calcium Stores in Low pH-Induced Regulation of Gap Junction Channels 3. Patch Clamp Studies of Gap Junctions 4. Gap Junctions in Adult Ventricular Muscle 5. The Physiology of Lens Junctions 6. Modulation of Cardiac Gap Junction Channel Activity by the Membrane Lipid Environment 7. Transjunctional Voltage Dependence of Gap Junction Channels 8. Dual Voltage Control is a Drosophilia Gap Junction Channel 9. Comparative Physiology of Cardiac Gap Junction Channels 10. Control of Gap Junction Conductance by Voltage in the Crayfish Nervous System 11. Modulatory Effect of the Transcellular Electrical Field on Gap Junction Conductance 12. Application of the Patch Clamp Technique to the Sutdy of Junctional Conductance 13. Junctional Coupling Modulation by Secretagogues in Two-Cell Pancreatic Systems 14. Characteristics of Single Channels of Pancreatic Acinar Gap Junctions Subject to Different Uncoupling Procedures 15. Cyclic AMP and Junctional Communication Viewed through a Multi-Biophysical 16. Regulatory Mechanisms of Gap Junctional Communication in Crayfish Axons 17. Properties of Gap Junctional Conductance in Retinal Horizontal Cells Section 2: Channels Studied in Reconstituted Systems 18. Reconstitution and Spectroscopy as Methodologies for Probing Junction Channel Protein Structure and Function 19. Reconstitution and Molecular Processing of MIP26K, a Putative Gap Junctional Component of the Lens Fiber Cell Membrane 20. Reconstitution of the Lens Channels Between Two Membranes 21. Reconstitution into Planar Lipid Bilayers- Application to the Sutdy of Lens MIP 22. Lens Cell Communication - From the Whole Organ to Single Channels 23. Connexin Forms Ion Channels in Single Artificial Membranes

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