2nd Edition

Biopsy Pathology in Colorectal Disease, 2Ed

    Biopsy Pathology in Colorectal Disease shows how the practising pathologist can extract the maximum of diagnostic value from biopsies of the colon, rectum and anus. With the advances in colonoscopic mucosal biopsy techniques these are amongst the most frequently encountered specimens in hospital histopathology departments. This new edition provides practising pathologists and those in allied disciplines with a thorough guide to the diagnosis of colorectal conditions, both common and rare, and offers expert guidance in the handling of biopsy specimens.

    The most valuable information for diagnostic interpretation of the various types of inflammatory disease is presented clearly and succinctly, minimizing the use of non-diagnostic terms such as non-specific colitis. Optimal ways of handling and examining polyps, the assessment of biopsies in motility disorders and the interpretation of biopsies of anal lesions are described. A rational classification and practical approach to dysplasia is presented.

    The early chapters describe how to recognize the many different features, both normal and abnormal, which can be regarded as signposts to diagnosis. The significance of these diagnostic signposts is briefly described and cross referenced to later chapters, in which the histological features of the specific diseases are covered in greater depth.

    1. Introduction
    2. Normal features
    3. Assessment of abnormalities: diagnostic signposts
    4. Infective colitis
    5. Ulcerative colitis
    6. Crohn's disease
    7. Ileoanal pouch pathology
    8. Pseudomembranous colitis
    9. Microscopic - colitis collagenous colitis, lymphocytic colitis and their variants
    10. Ischaemic colitis
    11. Iatrogenic disease
    12. The differential diagnosis of inflammatory bowel disease
    13. Disorders of motility
    14. Neoplasia in the colon and rectum and its classification
    15. Polyps
    16. The diagnosis of malignancy
    17. Dysplasia in inflammatory bowel disease
    18. Malignant tumours
    19. Anal biopsy
    20. Miscellaneous conditions


    Ian Talbot is a consulting pathologist at St. Marks and Northwick Park Hospitals and Professor of Histopatholgy at Imperial College Faculty of Medicine.
    Ashley Price is a consulting pathologist at Northwick Park and St Marks Hospitals and Professor of Gastrointestinal Pathology at Imperial College Faculty of Medicine.
    Manuel Salto-Tellez is Associate Professor at the Department of Pathology, Yong Loo Lin School of Medicine, at the National University of Singapore and Senior Consultant Pathologist at the National University Hospital in Singapore.

    "This book fulfils the needs of all clinicians and pathologists having to deal with various colorectal conditions, both common and rare, that are looking for an expert guidance for the diagnosis."

    Dr P Kitsanta, ACP News

    "This book is a must-keep and a worthy successor to the first edition ... One would hope that all surgical pathologists, whether practitioner or academic, residents or fellows, would read this superb publication."

    Gregory Y. Lauwers, Archives of Pathology and Laboratory Medicine