1st Edition

Biotechnological Relevance of Cytochrome P450 in Boosting Agricultural Production and Food Security

328 Pages 63 B/W Illustrations
by CRC Press

328 Pages 63 B/W Illustrations
by CRC Press

This book explores the untapped potential of cytochrome P450 monooxygenases , a highly versatile class of enzymes central to plant metabolism, defense, and growth. With over 95% of plant P450s still functionally uncharacterized, this volume serves as a comprehensive reference for understanding their multifaceted roles in modern agricultural biotechnology. Bridging molecular biology and... Read more

Chapter 1. Evolutionary History of Cytochrome P450 Genes in Plants

Wadzani Palnam Dauda, Peter Abraham, Elkanah Glen, Morumda Daji, Chidichukwu Ebere, Ajamu Temitope Ayinde, Maryam Peter Abraham, Samuel Toba Anjorin, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, and Henry Osaro Aisagbonhi

Chapter 2. Role of Cytochrome P450 monooxygenase in Crop Improvement

Alaba Adewole Adebayo, Abidemi David Adetulubo, Olufemi Gabriel Abimbola, Ayobami Christianah Olawusi, Adeniyi Philip Adebule, and Ayomide Emmanuel Fadiji 

Chapter 3. Cytochrome P450 Monooxygenase in Plant Defense Mechanisms Against Insect Pests

Rakesh Kumar, Vijay Kumar, Narendra Singh, Simardeep Kaur, Akshay Kumar Yogi, and Partha Chandra Mondal  

Chapter 4. The Role of Cytochrome P450 Monooxygenases in the Regulation of Plant Hormones 

Chukwu Chidiebere, Peter Abraham, Wadzani Palnam Dauda, Fatima B.J. Sawa, Stella Chinonye Ijemere, Adamu Waziri, Kapsiya Joel, and Henry Osaro Aisagbonhi

Chapter 5. Role of Cytochrome P450 Monooxygenase in Fatty Acids Metabolism of Plant

Israel Ogwuche Ogra, Grace Wabba Peter, Mariam Salifu, Jonathan Utos Emohchonne, Matthew Abu John, Ijeoma Princess, Blessing Ismaila, Peter Abraham, Wadzani Palnam Dauda, Uche Samuel Ndidi, Emmanuel Oluwadare Balogun, and Umezuruike Linus Opara

Chapter 6. Role of Cytochrome P450 Monooxygenase in Sterols Biosynthesis in Plant

Israel Ogwuche Ogra, Grace Wabba Peter, Johnson Kalu Ndukwe, John Wassagwa, Emeka John Dingwoke, Peter Abraham, Wadzani Palnam Dauda, Morumda Daji, Uche Samuel Ndidi, Emmanuel Oluwadare Balogun, and Umezuruike Linus Opara

Chapter 7. Role of Cytochrome P450 Monooxygenase in Biosynthesis and Functional Regulation of Plants Cell Wall Components

Wadzani Palnam Dauda, Peter Abraham, Ndukwe K. Johnson, Mayen Kalu, Dogara Tumba Elisha, Jonathan Utos Emohchonne, Ajamu Temitope Ayinde, Mary Olubunmi Adetula, Bukky Onyemowo Bamigbade, Israel Ogwuche Ogra, Maryam Peter Abraham, Samuel Toba Anjorin, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, and Henry Osaro Aisagbonhi

Chapter 8. Role of Cytochrome P450 Monooxygenase in Plant Antioxidant Metabolism

Elkanah Glen, Victor Duniya Sheneni, Faokunla Opeyemi Olubunmi, Wadzani Palnam Dauda, and Peter Abraham

Chapter 9. Role of Cytochrome P450 Monooxygenase in Plants Secondary Metabolites Biosynthesis

Israel Ogwuche Ogra, Grace Wabba Peter, Lamin B. S. Dibba, Justina Seun Obademi, Oluwafemi Abiodun Adepoju, Evelyn Omolola Ajibua, Peter Abraham, Wadzani Palnam Dauda, Henry Osaro Aisagbonhi, Uche Samue Ndidi, Emmanuel Oluwadare Balogun, and Umezuruike Linus Opara

Chapter 10. Unique Cytochrome P450 Monooxygenese with Biotechnologically Relevant Properties 

Peter Abraham, Wadzani Palnam Dauda, Daji Morumda, Elkanah Glen, Chukwu Chidiebere, Maryam Peter Abraham, Israel Ogwuche Ogra, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, Ishaku James Dantata, and Henry Osaro Aisagbonhi

Chapter 11. Role of Cytochrome P450 Monooxygenase in Plants Drought Stress Tolerance

Musa, S.I., Sheila Ojei, Ekene Chidozie, Onukwu, Ifeoma Sonia, Nathan Moses, Nathaniel Iboyi, Okoji Comfort, Harrison Ogala, and Okorie Maria Ezinne

Chapter 12. Role of Cytochrome P450 Monooxygenase in Plants Temperature Tolerance

Peter Abraham, Wadzani Palnam Dauda, Iroha Okechukwu Kalu, Chukwu Chidiebere, Elkanah Glen, Evelyn Omolola Ajibua, Maryam Peter Abraham, Jonathan Utos Emohchonne , Grace Wabba Peter Samuel Toba Anjorin, Charles Oluwaseun Adetunji, and Amrutha M. Lakshmi

Chapter 13. Role of Cytochrome P450 Monooxygenases in Plant Salinity Stress Tolerance

Partha Chandra Mondal, Shreosi Biswas, Biswajit Pramanik, and Anamika Das

Chapter 14. Role of Cytochrome P450 Monooxygenase in Plants Flooding Stress Tolerance

Grace Wabba Peter, Israel Ogwuche Ogra, Agatha Seember Ukande, Samson Usman, Samuel Olabode Charles, Aliyu Muhammad, Aliyu Salihu, Peter Abraham, Zainab Kasim Mohammed, and Wadzani Palnam Dauda

Chapter 15. Role of Cytochrome P450 Monooxygenases in Heavy Metal Stress Tolerance

Simardeep Kaur, Karishma Seem, Ekta Narwal, Kamlesh Kumar, Rakesh Kumar, Sandeep Jaiswal, and Binay Kumar Singh

Chapter 16. Role of Cytochrome P450 Monooxygenese in Herbicide Stress Tolerance

Peter Abraham, Wadzani Palnam Dauda, Dasoem Naanswan Joseph, Iroha Okechukwu Kalu, Samson Usman, Israel Ogwuche Ogra, Maryam Peter Abraham, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, and Ishaku James Dantata

Chapter 17. Role of Cytochrome P450 Monooxygenase in Cold Stress Tolerance

Wadzani Palnam Dauda, Peter Abraham, Ajamu Temitope Ayinde, Bukky Onyemowo Bamigbade, Mayen Kalu, Ndukwe K. Johnson, Mary Olubunmi Adetula, Jonathan Utos Emohchonne, Dogara Tumba Elisha, Maryam Peter Abraham, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, and Ishaku James Dantata

Chapter 18. Cytochrome P450 Monooxygenase Plant Defense Mechanisms Against Plant Parasitic Nematodes 

Peter Abraham, Wadzani Palnam Dauda, Caleb Iliya Jidere, Dasoem Naansuwan Joseph, Samson Usman, Maryam Peter Abraham, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, Daji Morumda, and Zainab Kasim Mohammed

Chapter 19. Cytochrome P450 Monooxygenase in Plant Defense Mechanisms Against Fungal Pathogens

Karuppiah Manikandan, K Nishmitha, Marimuthu Elangovan, and Shanmugam Velmurugan

Chapter 20. Cytochrome P450 Monooxygenase in Plant Defense Mechanisms Against Bacteria

Mela Ilu Luka, Elkanah Glen, Peter Abraham, Bulus Sharpshi Bdliya, and Wadzani Palnam Dauda

Chapter 21. Cytochrome P450 Monooxygenase Plant Defense Mechanisms Against Viruses

Peter Abraham, Wadzani Palnam Dauda, Elkanah Glen, Samson Usman, Boniface David Kashina, Olalekan Oyeleke Banwo, Ibrahim Umar Mohammed, Maryam Peter Abraham, Shuaibu S. Kahya, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, and Mathew Dada Alegbejo

Chapter 22. The Role of Cytochrome P450 Monooxygenase in Plant Xenobiotic Metabolism

Rakesh Kumar, Vijay Kumar, Kailash Pati Tripathi, Niraj Guleria, Randeep Kumar and Wadzani Palnam Dauda

Chapter 23. Cytochrome P450 Monooxygenase Roles in Allelopathic Plant-Plant Interactions

Peter Abraham, Wadzani Palnam Dauda, Samson Usman, Dasoem Naansuwan Joseph, Iroha Okechukwu Kalu, Maryam Peter Abraham, Ishaku James Dantata, Charles Oluwaseun Adetunji, Amrutha M. Lakshmi, and Zainab Kasim Mohammed

Chapter 24. Exploring the Role of Cytochrome 450 in Plants Biology in Genetic Engineering

Manjesh Saakre

Chapter 25. Cytochrome P450 Monooxygenases: Perspectives for Combining Biotic and Abiotic Stress Tolerant in Plant

Musa Ojeba Innocent, Afeez Idowu Temitope, Abdulhakeem Idris Abdulhakeem, Miracle Uwa Livinus, Mustapha Abdulsalam, Husna Farouq Ibrahim, Sikirula Abolaji Akande, Oluwafemi Adebayo Oyewole, and Charles Oluwaseun Adetunji

Chapter 26. Role of Genome-Structure-Function-Omic Analysis and Modern Biology in Regulating Cytochrome P450 Genes in Plants

Jerry Gbotemi Oni, Samuel Adeniyi Oyegbade, Emmanue Ojochegbe Mameh, Wurie Wopa Ahmed, Eniola Opeyemi Abiodun, Joseph Olaoluwa Akomolafe, Oluwafemi Adebayo Oyewole, and Charles Oluwaseun Adetunji

Chapter 27. Future Developments of Cold-Resistant Crops and the Role of Cytochrome P450 Monooxygenase

Damilare Isaiah Taiwo, Austine Atokolo, Ngozi Faith Omuekwu, Oluwafemi Adebayo Oyewole, and Charles Oluwaseun Adetunji

Chapter 28. Natural Diversity of Cytochrome P450 Enzymes and Their Role in Biofabrication of Plant’s Cell Wall Components

Mustapha Abdulsalam, Miracle Uwa Livinus, Musa Ojeba Innocent, Shehu-Alimi Elelu, Sunday Zeal Bala, Salami Olaitan Lateefat, Joshua Oluwatobi Akinola, Oluwafemi Adebayo Oyewole, and Charles Oluwaseun Adetunji

Biography

Wadzani Palnam Dauda is a researcher, an academic mentor, and a life coach currently serving as a faculty member at the Federal University Gashua, Nigeria. His illustrious career is marked by over 130 scholarly publications reflecting his unwavering commitment to advancing scientific discourse. He was ranked number 10th by SciVal/SCOPUS in two different fields, Biological Sciences and Agricultural Science, among 500 prolific authors from 58 different countries in Africa. He holds esteemed positions, including Editorial Board memberships for Frontiers in Genome Editing, PLOS ONE, Springer Nature, Taylor & Francis, and Elsevier journals. Recognized for his scholarly eminence, he has received accolades and grants from prestigious organizations such as the Bill & Melinda Gates Foundation, UNESCO, Regeneron, American Phytopathological Society (APS), American Society of Microbiology (ASM), Department of Biotechnology (DBT) India, World Academy of Science (TWAS) Italy, Tertiary Education Trust Fund (TETFUND), and the prestigious M.J. Thirumalachar Merit Award for Young Scientists in 2022. His extensive research interests encompass diverse domains, including disease detection, mycotoxicology, agricultural microbiology, genome editing, and bioinformatics. His intellectual versatility is further highlighted by his memberships in renowned societies such as the American Society for Biochemistry and Molecular Biology (ASBMB), International Society for Computational Biology (ISCB), International Society for Molecular Plant–Microbe Interactions (IS-MPMI), Society for Applied Microbiology (SfAM), American Phytopathological Society (APS), American Society for Microbiology (ASM), the Nigerian Young Academy (NYA), and the Royal Society of Biology (RSB), UK. He has been invited as a keynote speaker at various national and international institutions and conferences, including the UNESCO International Centre for Biotechnology in Nsukka, Nigeria; the Doctoral Academy of Nigeria (DAN); National Open University of Nigeria (NOUN); University of Jos; Nnamdi Azikiwe University; Annamalai University; and several others. He holds the esteemed title of Fellow of the Society for Plant Research (FSPR). He is the Director of Research and Development at the Academic and Grant Writing Enclave (AGE).

Charles Oluwaseun Adetunji is a distinguished scholar in the Department of Microbiology, Faculty of Science, Edo State University, Uzairue (EDSU), Edo State, Nigeria. His research integrates biological techniques and microbial bioprocesses to advance sustainable development goals and foster agrarian transformation through impactful teaching, research, and community service. He currently serves as the Director of Research and Innovation and Chairman of the Grant Committee at EDSU, having previously held positions including Acting Director of Intellectual Property and Technology Transfer, Head of Department, Sub-Dean, and Dean of the Faculty of Science. He delivered the university’s 11th Inaugural Lecture, titled "Microbial Biosphere: The Global Impact and Underexplored Currency," and was elected as a Senate representative for the Vice-Chancellor selection committee.

He began his career at the Nigerian Stored Products Research Institute (NSPRI), Ilorin, where he advanced from Research Officer II to Principal Scientist. His pioneering work improved food safety, shelf-life extension, and post-harvest technology. He later joined Landmark University, Omu-Aran, and served as a visiting fellow at the Hebrew University of Jerusalem and Wageningen Centre for Development and Innovation, Netherlands.

He is a fellow of the Royal Society of Biology (UK), the Biotechnology Society of Nigeria, the Nigerian Society of Microbiology, and the Nigerian Young Academy. He holds visiting professorships at Precious Cornerstone University, Trinity University, and the University of Johannesburg, among others. He serves as an external examiner and assessor for universities across Nigeria, Finland, South Africa, and Ethiopia and as an instructor at the University of the People, USA.

His global recognition includes being listed in Stanford University’s "World’s Top 2% Scientists" rankings (2023–2025) and named among ScholarGPS’s 2024 Top 0.5% of Scholars globally in Life Sciences and Microbiology. With over 900 publications, including 60 books, 600 book chapters, and several patents, he has published in top journals such as Nature Medicine and The Lancet. His Google Scholar i10-Index exceeds 260. He is ranked first among Nigeria’s top 500 prolific authors in Microbiology and Agricultural Sciences by SciVal/SCOPUS (Elsevier). He also serves as a book series editor with Wiley, Elsevier, Springer, and Taylor & Francis.

A global scientific leader, he has delivered keynote and plenary lectures at over 100 international conferences and reviews manuscripts for more than 100 journals, including Nature and PLOS One. His research contributions to the UN Sustainable Development Goals have been acknowledged by Elsevier.

He currently presides as President and Chairman of the Governing Council of the Nigerian Bioinformatics and Genomics Network Society and Vice-President of the Biotechnology Society of Nigeria. He has served on international committees, including the African Union Development Agency–NEPAD, American Society of Tropical Medicine and Hygiene, and Africa Research Excellence Fund (UK). Additionally, he consults for the Governments of Serbia and South Africa and coordinates the 1000 Scientific Trials Programme by Harvest Harmonics (USA) across 58 countries.

A mentor to numerous scholars globally, he guides postgraduate and postdoctoral researchers in translational and innovative science. Through his leadership, EDSU has signed over 30 international MoUs. As convener of the annual Recent Advances in Biotechnology Conference, he continues to inspire groundbreaking collaboration and innovation in microbiology, biotechnology, and bioinformatics.