1st Edition
Biotic Type Antioxidants: the prospective search area for novel chemical drugs
584 Pages
by
CRC Press
560 Pages
by
Routledge
Also available as eBook on:
The discovery of molecular and cellular mechanisms of pathology, together with the present data on drug treatment result in enhanced drug design and testing. The known mechanisms of biological activity as displayed by ascorbic acid and other natural reductones are the reason that they are considered to be physiologically compatible antioxidants, many of which are trace elements in food. The... Read more
Preface
CHAPTER 1. REDUCTONES AS A VARIETY OF ANTIOXIDANTS OF THE BIOTIC TYPE
1.1. Introduction
1.2. Natural reductones
1.2.1. Asorbic acid (AA)
1.2.2. Coumarin reductones of the aliphatic type
1.2.3. Polyphenoles of vegetable and animal origin
1.2.4. Other heterocyclic compounds
1.3. Conclusion
CHAPTER 2. ANTITUMOUR POTENTIAL OF SUPEROXIDE DISMUTASE MODEL
2.1. Introduction
2.1.1. The notion of superoxide dismutase models
2.1.2. Superoxide dismutase and cancer
2.1.3. SOD models and cancer
2.1.4. Copper metabolism and oncological diseases
2.1.5. Antitumour effect of inorganic copper salts
2.2. The search for antitumour agents among complex copper compounds
2.2.1. Salicylate SOD models
2.2.2. Other carboxylate SOD models
2.2.3. Amino acid and peptide SOD models
2.2.4. Other types of SOD models
2.2.5. Stable SOD models
2.2.6. The search for effective chelators
2.2.7. Concept of iron chelators
2.2.8. Principles of SOD model design
2.3. Molecular mechanisms of the SPD model antitumour effects
2.3.1. SOD models as anticarcinogenes
2.3.2. SOD models as antitumour agents
2.3.3. Prooxidant activity of SOD models
2.3.4. Mechanisms of physiological compatibility of SOD models
2.3.5. Is a universal antioxidant possible?
CHAPTER 3. HOW TO TRANSFORM AVAILABLE KNOWLEDGE INTO SPECIFIC ELABORATIONS
3.1. Raw material sources and technological scheme
3.2. Estimation of the possibilities of the technological scheme suggested by the assortment of products
3.3. Conclusion
Subject index
List of abbreviations
Biography
Parfenov, E A.
