424 Pages 107 Color & 135 B/W Illustrations
by CRC Press

424 Pages 107 Color & 135 B/W Illustrations
by CRC Press

This second edition comes at a time of a paradigm shift in understanding of the molecular pathology and neuroscience of brain and spinal tumors of childhood and their mechanisms of growth within the developing brain. Excellent collaborative translational networks of researchers are starting to drive change in clinical practise through the need to test many ideas in trials and scientific... Read more

List of Contributors

1. Introduction

David A. Walker, Giorgio Perilongo, Roger E. Taylor, and Ian F. Pollack

2. Epidemiology of Childhood Brain Tumors

Richard J. McNally and Paul Graham Fisher

3. Clinical Presentation and Associated Syndromes of Brain Tumor

David Walker, JoFen Liu, and Dhurgsharna Shanmugavadivel

4. Pediatric Central Nervous System Tumors as Phenotypic Manifestation of Cancer Predisposition Syndromes

Giorgio Perilongo, Irene Toldo, and Stefano Sartori

5. Anatomical and Biological Imaging of Pediatric Brain Tumor

Rob A. Dineen, Shivaram Avula, Andrew C. Peet, Giovanni Morana, and Monika Warmuth- Metz

6. Neurosurgical Techniques and Strategies

Jonathan E. Martin, Ian F. Pollack, and Robert F. Keating

7. Radiotherapy for Pediatric Central Nervous System Tumors – Techniques and Strategies

Nicola Thorp

8. Physical and Cognitive Rehabilitation for Children with Brain and Spinal Tumors

Alexandra M. Gaynor, Helen Hartley, and Stephen A. Sands

9. Drug Delivery

Gudrun Fleischhack, Martin Garnett, and Kévin Beccaria

10. Low- grade Glioma Presenting in the Optic Pathways and Hypothalamus (NF1. and Sporadic)

Peter M.K. de Blank, Ian Simmons, Astrid Sehested, and Michael J. Fisher

11. Low- grade Glioma: Principles of Diagnosis and Drug Treatment

Pablo Hernáiz Driever, Olaf Witt, Astrid Gnekow, Daniela Kandels, and Mark Kieran

12. High- grade Glioma

Donald C. Macarthur, Christof M. Kramm, and Matthias A. Karajannis

13. Diff use Intrinsic Pontine Glioma

Katherine E. Warren, Carolyn R. Freeman, and Dannis G. van Vuurden

14. Embryonal Tumors

Simon Bailey and Jeff Michalski

15. Ependymoma in Childhood and Adolescence

Richard Grundy and Eric Bouffet

16. Germ Cell Tumors of the Central Nervous System

Matthew J. Murray, Ute Bartels, and James C. Nicholson

17. Atypical Teratoid / Rhabdoid Tumors – AT/ RT

Michael C. Frühwald, Jaclyn A. Biegel, and Susan N. Chi

18. Craniopharyngioma

Hermann L. Müller, Claire Alapetite, and Jeffrey Wisoff

19. Choroid Plexus Tumors and Meningiomas

Kenneth K. Wong, Elwira Szychot, Jennifer A. Cotter, and Mark Krieger

20. Pediatric Spinal Tumors

Rajiv R. Iyer, Nir Shimony, Mohammad Hassan A. Noureldine, Eric Bouffet, and George I. Jallo

21. Late Effects of Treatment for Childhood Brain and Spinal Tumors

Ralph Salloum, Katherine Baum, Melissa Gerstle, Helen Spoudeas, and Susan R. Rose

22. The Power of Patient Advocacy in Pediatric Neuro-oncology

Kathy Oliver, Susan Awrey, Mark Brougham, Gloria Garcia Castellvi, Anita Granero, Rakesh Jalali, Sacha Langton-Gilks, Yuko Moue, Kathy Riley, Bonita Suckling, Hisato Tagawa, and Raees Tonse

Index

Biography

David A. Walker is Professor Paediatric Oncology, School of Medicine, University of Nottingham, Nottingham, UK
Giorgio Perilongo is Director, Department of Woman’s and Child’s Health, Division of Pediatrics, University of Padua, Padua, Italy
Roger E. Taylor is Professor of Clinical Oncology, College of Medicine, Swansea University; Honorary Consultant Clinical Oncologist, South West Wales Cancer Centre, Singleton Hospital, Swansea, UK
Ian F. Pollack is Chief, Pediatric Neurosurgery, Children's Hospital of Pittsburgh, Leland Albright Distinguished Professor of Neurological Surgery, Vice Chairman for Academic Affairs, Department of Neurological Surgery, Co-Director, UPCI Brain Tumor Program, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA

"a clearly written text that provides a relevant overview … succinct and streamlined, making it a practical yet still reasonably comprehensive resource"

- Esther Dupepe, MSPH, MD (Ochsner Health System)