Bronchopulmonary Dysplasia: 1st Edition (Paperback) book cover

Bronchopulmonary Dysplasia

1st Edition

Edited by Steven H. Abman

CRC Press

520 pages | 250 B/W Illus.

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Paperback: 9781138115040
pub: 2017-05-31
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Hardback: 9781420076912
pub: 2009-09-24
eBook (VitalSource) : 9780429147692
pub: 2009-09-24
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Addressing the dramatic number of children diagnosed with bronchopulmonary dysplasia (BPD) in recent years, Bronchopulmonary Dysplasia provides pulmonologists, critical care specialists, and pediatricians with up-to-date diagnostic and treatment techniques and therapies to effectively manage all BPD cases.

Key benefits include: groundbreaking research-covers the latest discoveries in BPD genetics, epidemiology, and pathogenesis, as well as current-and sometimes controversial-therapies to help clinicians properly detect the disease and choose the best treatment plan expert editorship-Dr. Steven H. Abman, Director of the Pediatric Heart Lung Center, and a team of 49 highly experienced and respected contributors provide authoritative advice physicians can rely on timely, stand-alone resource-this one-stop, convenient guide discusses all of the current, critical information clinicians need to manage the increase in diagnosed children well-organized content-four clear and highly structured sections give busy physicians quick access to the key diagnostic and therapeutic intricacies of BDP

Table of Contents

Part I: Mechanisms of Lung Growth and Development

Genetic Mechanisms of Lung Development and Bronchopulmonary Dysplasia: An Integrative View

David Warburton and Wei Shi

Growth Factors and Cell-Cell Interactions During Lung Development

Emily Fox and Martin Post

Basic Mechanisms of Alveolarization

Jacques R. Bourbon, Christophe Delacourt, and Olivier Boucherat

Lung Vascular Development

Alison A. Hislop

Part II: Mechanisms of Disrupted Lung Development and Repair in the Pathobiology of BPD

Oxidative and Nitrosative Stress and Bronchopulmonary Dysplasia

Richard L. Auten and Carl White

Prenatal Inflammation and Immune Responses of the Preterm Lung

Suhas Kallapur, Alan H. Jobe, and Boris W. Kramer

Inflammatory Mechanisms in Bronchopulmonary Dysplasia

Christian P. Speer

Disruption of Lung Vascular Development

William M. Maniscalco and Vineet Bhandari

Pulmonary Endothelial Progenitor Cells and Bronchopulmonary Dysplasia

Rebecca S. Rose, David A. Ingram, and Mervin C. Yoder

Effects of Mesenchymal Stem Cell Therapy in BPD

Bernard The´baud and Stella Kourembanas

Altered Growth Factor Signaling in the Pathogenesis of BPD

A. Keith Tanswell, Sanna Padela, and Robert P. Jankov

Part III: Clinical Aspects of BPD and its Management

Evolving Clinical Features of the New Bronchopulmonary Dysplasia

Eduardo Bancalari and Nelson Claure

Epidemiology of Bronchopulmonary Dysplasia

Linda J. Van Marter

Definitions of Bronchopulmonary Dysplasia and the Use of Benchmarking to Compare Outcomes

Michele C. Walsh

Genetics of Bronchopulmonary Dysplasia

Vineet Bhandari

Role of Management in the Delivery Room and Beyond in the Evolution of Bronchopulmonary Dysplasia

Maximo Vento and Ola Didrik Saugstad

Mechanical Ventilation: Early Strategies to Decrease BPD 314

Tina A. Leone and Neil N. Finer

Lung Function, Structure and the Physiologic Basis for Mechanical Ventilation of Infants with Established BPD

Robert G. Castile and Leif D. Nelin

Pulmonary Vascular Disease in Bronchopulmonary Dysplasia: Physiology, Diagnosis, and Treatment

Peter M. Mourani and Steven H. Abman

Drug Therapies in the Management of BPD

Henry L. Halliday

Lung Function Abnormalities in Infants and Children with Bronchopulmonary Dysplasia

Marco Filippone and Eugenio Baraldi

Long-Term Outcomes of Infants with BPD

Anne Greenough

Neurodevelopmental Outcomes of Children with Bronchopulmonary Dysplasia

Joy V. Browne

Part IV: Emerging Therapies in the Treatment of BPD

Inhaled Nitric Oxide in Premature Infants for the Prevention and Treatment of BPD

John P. Kinsella, Philip L. Ballard, Roberta A. Ballard, and Michael D. Schreiber

Vitamin A in the Prevention of Bronchopulmonary Dysplasia

Namasivayam Ambalavanan and Waldemar Carlo

The Use of Antioxidants to Prevent or Ameliorate Bronchopulmonary Dysplasia

Jonathan M. Davis and Richard Parad

Low-Dose Glucocorticoids for Prevention or Treatment of Bronchopulmonary Dysplasia

Kristi Watterberg

About the Series

Lung Biology in Health and Disease

Learn more…

Subject Categories

BISAC Subject Codes/Headings:
MEDICAL / Pediatrics
MEDICAL / Pulmonary & Thoracic Medicine