1st Edition

Bronchopulmonary Dysplasia

Edited By Steven H. Abman Copyright 2010
    520 Pages 250 B/W Illustrations
    by CRC Press

    520 Pages 250 B/W Illustrations
    by CRC Press

    Addressing the dramatic number of children diagnosed with bronchopulmonary dysplasia (BPD) in recent years, Bronchopulmonary Dysplasia provides pulmonologists, critical care specialists, and pediatricians with up-to-date diagnostic and treatment techniques and therapies to effectively manage all BPD cases.
    Key benefits include: groundbreaking research-covers the latest discoveries in BPD genetics, epidemiology, and pathogenesis, as well as current-and sometimes controversial-therapies to help clinicians properly detect the disease and choose the best treatment plan expert editorship-Dr. Steven H. Abman, Director of the Pediatric Heart Lung Center, and a team of 49 highly experienced and respected contributors provide authoritative advice physicians can rely on timely, stand-alone resource-this one-stop, convenient guide discusses all of the current, critical information clinicians need to manage the increase in diagnosed children well-organized content-four clear and highly structured sections give busy physicians quick access to the key diagnostic and therapeutic intricacies of BDP

    Part I: Mechanisms of Lung Growth and Development
    Genetic Mechanisms of Lung Development and Bronchopulmonary Dysplasia: An Integrative View
    David Warburton and Wei Shi
    Growth Factors and Cell-Cell Interactions During Lung Development
    Emily Fox and Martin Post
    Basic Mechanisms of Alveolarization
    Jacques R. Bourbon, Christophe Delacourt, and Olivier Boucherat
    Lung Vascular Development
    Alison A. Hislop
    Part II: Mechanisms of Disrupted Lung Development and Repair in the Pathobiology of BPD
    Oxidative and Nitrosative Stress and Bronchopulmonary Dysplasia
    Richard L. Auten and Carl White
    Prenatal Inflammation and Immune Responses of the Preterm Lung
    Suhas Kallapur, Alan H. Jobe, and Boris W. Kramer
    Inflammatory Mechanisms in Bronchopulmonary Dysplasia
    Christian P. Speer
    Disruption of Lung Vascular Development
    William M. Maniscalco and Vineet Bhandari
    Pulmonary Endothelial Progenitor Cells and Bronchopulmonary Dysplasia
    Rebecca S. Rose, David A. Ingram, and Mervin C. Yoder
    Effects of Mesenchymal Stem Cell Therapy in BPD
    Bernard TheĀ“baud and Stella Kourembanas
    Altered Growth Factor Signaling in the Pathogenesis of BPD
    A. Keith Tanswell, Sanna Padela, and Robert P. Jankov
    Part III: Clinical Aspects of BPD and its Management
    Evolving Clinical Features of the New Bronchopulmonary Dysplasia
    Eduardo Bancalari and Nelson Claure
    Epidemiology of Bronchopulmonary Dysplasia
    Linda J. Van Marter
    Definitions of Bronchopulmonary Dysplasia and the Use of Benchmarking to Compare Outcomes
    Michele C. Walsh
    Genetics of Bronchopulmonary Dysplasia
    Vineet Bhandari
    Role of Management in the Delivery Room and Beyond in the Evolution of Bronchopulmonary Dysplasia
    Maximo Vento and Ola Didrik Saugstad
    Mechanical Ventilation: Early Strategies to Decrease BPD 314
    Tina A. Leone and Neil N. Finer
    Lung Function, Structure and the Physiologic Basis for Mechanical Ventilation of Infants with Established BPD
    Robert G. Castile and Leif D. Nelin
    Pulmonary Vascular Disease in Bronchopulmonary Dysplasia: Physiology, Diagnosis, and Treatment
    Peter M. Mourani and Steven H. Abman
    Drug Therapies in the Management of BPD
    Henry L. Halliday
    Lung Function Abnormalities in Infants and Children with Bronchopulmonary Dysplasia
    Marco Filippone and Eugenio Baraldi
    Long-Term Outcomes of Infants with BPD
    Anne Greenough
    Neurodevelopmental Outcomes of Children with Bronchopulmonary Dysplasia
    Joy V. Browne
    Part IV: Emerging Therapies in the Treatment of BPD
    Inhaled Nitric Oxide in Premature Infants for the Prevention and Treatment of BPD
    John P. Kinsella, Philip L. Ballard, Roberta A. Ballard, and Michael D. Schreiber
    Vitamin A in the Prevention of Bronchopulmonary Dysplasia
    Namasivayam Ambalavanan and Waldemar Carlo
    The Use of Antioxidants to Prevent or Ameliorate Bronchopulmonary Dysplasia
    Jonathan M. Davis and Richard Parad
    Low-Dose Glucocorticoids for Prevention or Treatment of Bronchopulmonary Dysplasia
    Kristi Watterberg


    Steven H. Abman