This two-volume handbook provides important information concerning the development, implementation, evaluation, uses, advantages, and limitations of a wide variety of animal model of pulmonary disease. While the work focuses on stepwise procedures for inducing and quantifying disease, additional emphasis is placed on each model's relationship to human counterparts and on comparisons with similar models of injury. Thus, even the novice researcher will be able to more sharply define a particular research question, find suitable animal models for study, gain access to specialized techniques, and evaluate results within the context of an up-to-date body of information about related forms of lung diseases.
Table of Contents
1. Animal Models of Hyperoxic Lung Injury 2. Ozone-Induced Lung Injury 3. Sheep as an Animal Model of Endotoxemia-Induced Diffuse Lung Injury 4. injury to the Isolated, Perfused Lung Induced by Phorbol Myristate Acetate 5. Nitrosourethane-Induced Lung Injury 5. Immune Complex Injury 6. Bleomycin-Induced Pulmonary Fibrosis 7. Amiodarone-Induced Pulmonary Fibrosis 8. The Paraquat Model of Lung Fibrosis 9. Radiation-Induced Interstitial Lung Disease 10. Silica-Induced Pulmonary Fibrosis 11. Lung Response to Cigarette Smoke Inhalation: An Animal Model