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1st Edition

CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases



  • Available for pre-order. Item will ship after October 30, 2021
ISBN 9780367542863
October 30, 2021 Forthcoming by CRC Press
268 Pages 3 Color & 12 B/W Illustrations

 
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Book Description

The CRISPR-Cas9 genome-editing system is creating a revolution in the science world. In the laboratory, CRISPR-Cas9 can efficiently be used to target specific genes, correct mutations and regulate gene expression of a wide array of cells and organisms, including human cells. CRISPR-/Cas9 Based Genome Editing for Treating Genetic Disorders and Diseases is a unique reading material for college students, academicians, and other health professionals interested in learning about the broad range of applications of CRISPR/Cas9 genetic scissors. Some topics included in this book are: the role of the CRISPR/Cas9 system in neuroscience, gene therapy, epigenome editing, genome mapping, cancer, virus infection control strategies, regulatory challenges and bioethical considerations.

Table of Contents

The CRISPR/Cas9 Genome-editing System: Principles and Applications

Cecilia Pop-Bica, Andreea Nutu, Roxana Cojocneanu, Sergiu Chira and Ioana Berindan-Neagoe

Recent Applications of CRISPR-Cas9 in Genome Mapping and Sequencing

Dharma Varapula, Lahari Uppuluri and Ming Xiao

Gene Editing and Genetic Disorders: Ethical and Legal Concerns

Vicente Bellver and Federico de Montalvo

Political, Regulatory and Ethical Considerations of the CRISPR/Cas Genome Editing Technology

Eduardo Rodriguez Yunta and Luis María Vaschetto

CRISPR/Cas and Gene Therapy: An Overview

Luis María Vaschetto

CRISPR and Cancer: From Bench to Clinic

Muhammad Usama Tariq and Amina Chaudhry

The Advances of the CRISPR/Cas9 Technology for Correcting Genetic Disorders: Using Sarcoma as a Model System

Pichaya Thanindratarn, Dylan C. Dean, Francis J. Hornicek and Zhenfeng Duan

CRISPR/Cas9 Technology as a Strategy Against Viral Infections

Huafeng Lin, Haizhen Wang, Jun He, Xiangwen Peng, Aimin Deng, Lei Shi, Lei Ye and Hanyue Gong

CRISPR/Cas9-based Genome and Epigenome Editing in Neuroscience Research

Nereo Kalebic and Wieland B. Huttner

Non-viral Alternatives to delivery of CRISPR-Cas Gene Editing Components

Kate Senger and Benjamin Haley

CRISPR Medicine: Advance, Progress and Challenges

Guillermo Ureña-Bailén, Justin S Antony, Yujuan Hou, Janani Raju, Andres Lamsfus-Calle, Alberto Daniel-Moreno, Rupert Handgretinger and Markus Mezger

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Editor(s)

Biography

Luis María Vaschetto received his Doctorate in Biological Sciences from Universidad Nacional de Córdoba (Argentina). He was a postdoctoral researcher at the Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET) and a Research Associate at the South Dakota State University (SDSU). His research focuses on understanding the epigenetic mechanisms involved in plant and animal development, as well as their effects on human health and diseases.