1st Edition
Calming the Brain Benzodiazepines and Related Drugs from Laboratory to Clinic
192 Pages
by
CRC Press
192 Pages
by
CRC Press
Also available as eBook on:
This book covers the entire field of research in the area of minor tranquillizers and its application to current clinical practice in the treatment of anxiety and insomnia. These drugs are principally the benzodiazepines and related drugs with a similar mechanism of action, such as zolpidem and zopiclone. The molecular mechanism of action of benzodiazepines is described, focussing on the... Read more
1. The Story of Modern Tranquilliser Drugs 2. Interaction of the Benzodiazepines with the GABA^OA Receptor 3. Structural Characterisation of the GABA^OA Receptor 4. Functional Characterisation of the GABA^OA Receptor 5. Structures of Benzodiazepine Recognition Site Ligands 6. Behavioural Pharmacology 7. Pharmacokinetic Determinants of Clinical Activity 8. Benzodiazepines Drugs in Sleep Disorders 9. Benzodiazepines as Anxiolytics 10. Benzodiazepines: Anticonvulsant and Other Clinical Uses 11. Conclusions
Biography
Adam Doble (Author) , Ian Martin (Author) , David J. Nutt (Author)
