1st Edition

Carbohydrate-Modifying Biocatalysts

Edited By Peter Grunwald Copyright 2012
    846 Pages 82 Color & 191 B/W Illustrations
    by Jenny Stanford Publishing

    This book provides an actual overview of structure, function, and application of carbohydrate-modifying biocatalysts. Unlike amino acids and nucleic acids, carbohydrates have been disregarded for a long time by the scientific community, mainly due to their complex structure and a lack of suited experimental methods for structure determination. Meanwhile, the situation changed with increasing knowledge about carbohydrates, glycoconjugates, and carbohydrate-modifying enzymes together with the key roles they play in biological processes such as recognition, signal transduction, and immune responses. An outcome of research activities in glycoscience, which, at the same time, is of great general interest, is the development of several new pharmaceuticals against serious diseases such as malaria, cancer, and various storage diseases.

    Basics in Carbohydrate Chemistry, H. Hühnerfuss

    Glycoconjugates: An Overview, P. Grunwald

    Oligosaccharides and Glycoconjugates in Recognition Processes, T. K. Lindhorst

    Glycoside Hydrolases, M. Kitaoka

    Disaccharide Phosphorylases: Mechanistic Diversity and Application in Glycosciences, C. Luley-Goedl and B. Nidetzky

    Enzymatic and Chemo-Enzymatic Synthesis of Nucleotide Sugars: Novel Enzymes, Novel Substrates, Novel Products, and Novel Routs, L. Engels and L. Elling

    Iteratively Acting Glycosyltransferases, M. Luzhetska and A. Bechthold

    Bacterial Glycosyltransferases Involved in Molecular Mimicry of Mammalian Glycans, W. Wakarchuk

    Sulfotransferases and Sulfatases: Sulfate Modification of Carbohydrates, Eli Chapman and Sarah R. Hanson

    Glycosylation in Health and Disease, P. Grunwald

    Sialic Acid Derivatives, Analogs and Mimetics as Biological Probes and Inhibitors of Sialic Acid Recognizing Proteins, J. Tiralongo and T. Haselhorst

    Enzymes of the Carbohydrate Metabolism and Catabolism for Chemoenzymatic Syntheses of Complex Oligosaccharides, J. Thimm and J. Thiem

    From Gene to Product — Tailor-Made Oligosaccharides and Polysaccharides by Enzyme and Substrate Engineering, J. Seibel

    Synthesis and Modification of Carbohydrates via Metabolic Pathway Engineering in Microorganisms, X.-W. Liu, L. Li, H.-T. Gao, L.-J. Dang, and P. G. Wang

    Metabolic Pathway Engineering for Hyaluronic Acid Production, E. Marcellin, Wendy Y. Chen, and L. K. Nielsen

    Microbial Rhamnolipids, M. M. Müller, B. Hörmann, C. Syldatk, and R. Hausmann

    Chitin-Converting Enzymes, K. Moß, S. Zibek, T. Hirth, and S. Rupp

    Linear and Cyclic Oligosaccharides, H. Taniguchi

    Fungal Degradation of Plant Oligo- and Polysaccharides, R. P. de Vries, M. Nadal, J. van der Brink, D. A. Vivas-Duarte, and H. Stålbrand

    Bacterial Strategies for Plant Cell Wall Degradation and Their Genomic Information, Y. Tamaru and R. H. Doi

    Design of Efficient Multi-Enzymatic Reactions for Cellulosic Biomass Processing, Anne S. Meyer


    Peter Grunwald

    "This is an excellent compilation of the latest research in the field of carbohydrate-modifying biocatalysts written by highly recognized experts in the field. With glycoscience and biocatalysis emerging as fundamental contributors to a diverse array of scientific disciplines ranging from pharmaceutical development to renewable energy, this book is particularly timely and should serve as an excellent reference for inspiring scientists and students."
    —Prof. Jon S. Thorson - University of Wisconsin School of Pharmacy, USA