1st Edition

Carbohydrate-Modifying Biocatalysts

Edited By

Peter Grunwald

ISBN 9789814241670
Published October 19, 2011 by Jenny Stanford Publishing
846 Pages 82 Color & 191 B/W Illustrations

USD $420.00

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Book Description

This book provides an actual overview of structure, function, and application of carbohydrate-modifying biocatalysts. Unlike amino acids and nucleic acids, carbohydrates have been disregarded for a long time by the scientific community, mainly due to their complex structure and a lack of suited experimental methods for structure determination. Meanwhile, the situation changed with increasing knowledge about carbohydrates, glycoconjugates, and carbohydrate-modifying enzymes together with the key roles they play in biological processes such as recognition, signal transduction, and immune responses. An outcome of research activities in glycoscience, which, at the same time, is of great general interest, is the development of several new pharmaceuticals against serious diseases such as malaria, cancer, and various storage diseases.

Table of Contents

Basics in Carbohydrate Chemistry, H. Hühnerfuss

Glycoconjugates: An Overview, P. Grunwald

Oligosaccharides and Glycoconjugates in Recognition Processes, T. K. Lindhorst

Glycoside Hydrolases, M. Kitaoka

Disaccharide Phosphorylases: Mechanistic Diversity and Application in Glycosciences, C. Luley-Goedl and B. Nidetzky

Enzymatic and Chemo-Enzymatic Synthesis of Nucleotide Sugars: Novel Enzymes, Novel Substrates, Novel Products, and Novel Routs, L. Engels and L. Elling

Iteratively Acting Glycosyltransferases, M. Luzhetska and A. Bechthold

Bacterial Glycosyltransferases Involved in Molecular Mimicry of Mammalian Glycans, W. Wakarchuk

Sulfotransferases and Sulfatases: Sulfate Modification of Carbohydrates, Eli Chapman and Sarah R. Hanson

Glycosylation in Health and Disease, P. Grunwald

Sialic Acid Derivatives, Analogs and Mimetics as Biological Probes and Inhibitors of Sialic Acid Recognizing Proteins, J. Tiralongo and T. Haselhorst

Enzymes of the Carbohydrate Metabolism and Catabolism for Chemoenzymatic Syntheses of Complex Oligosaccharides, J. Thimm and J. Thiem

From Gene to Product — Tailor-Made Oligosaccharides and Polysaccharides by Enzyme and Substrate Engineering, J. Seibel

Synthesis and Modification of Carbohydrates via Metabolic Pathway Engineering in Microorganisms, X.-W. Liu, L. Li, H.-T. Gao, L.-J. Dang, and P. G. Wang

Metabolic Pathway Engineering for Hyaluronic Acid Production, E. Marcellin, Wendy Y. Chen, and L. K. Nielsen

Microbial Rhamnolipids, M. M. Müller, B. Hörmann, C. Syldatk, and R. Hausmann

Chitin-Converting Enzymes, K. Moß, S. Zibek, T. Hirth, and S. Rupp

Linear and Cyclic Oligosaccharides, H. Taniguchi

Fungal Degradation of Plant Oligo- and Polysaccharides, R. P. de Vries, M. Nadal, J. van der Brink, D. A. Vivas-Duarte, and H. Stålbrand

Bacterial Strategies for Plant Cell Wall Degradation and Their Genomic Information, Y. Tamaru and R. H. Doi

Design of Efficient Multi-Enzymatic Reactions for Cellulosic Biomass Processing, Anne S. Meyer

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"This is an excellent compilation of the latest research in the field of carbohydrate-modifying biocatalysts written by highly recognized experts in the field. With glycoscience and biocatalysis emerging as fundamental contributors to a diverse array of scientific disciplines ranging from pharmaceutical development to renewable energy, this book is particularly timely and should serve as an excellent reference for inspiring scientists and students."
—Prof. Jon S. Thorson - University of Wisconsin School of Pharmacy, USA