1st Edition

Carbon-Based Nanocarriers for Drug Delivery

    348 Pages 55 B/W Illustrations
    by CRC Press

    Carbon-Based Nanocarriers for Drug Delivery enlists the latitudes and advancements in the synthesis processes, functionalization, and applications of carbon-based nanomaterials (CBNs) in targeted drug delivery systems (DDSs). It covers the applicability and suitability of CBNs as nanocarriers for efficient drug delivery application via elucidating the recent advancements in CBNs, their functionalized and innovative derivatives, and the relevant case studies. The book explores the necessity, efficacy, toxicological aspects, and challenges for the application of CBN in targeted DDSs. Some of the features of this book are provided as follows:

    • Provides elaborative description on significance and adaptability of carbon-based nanomaterial in targeted drug delivery for wide ranges of therapeutics
    • Delivers a full-spectrum discussion on drug delivery through carbon-based nanocarriers
    • Explores each carbon-based nanocarrier fundamentally for its drug and gene-delivery-related applications
    • Describes critical discussion on various toxicological effects over the utilization of these nanocarriers
    • Embraces existing as well as novel technologies/methodologies related to the synthesis and functionalization of CBNs, including graphene, graphene oxide, carbon quantum dots, carbon nanotube, fullerene, and smart carbon-based nanocarriers

    This book is aimed at researchers and graduate students in materials and pharmaceutical engineering, including drug delivery systems.

    1. Fundamentals of carbon-based nanomaterials. 2. Advancement in drug delivery systems. 3. Graphene-based nanocarriers as drug delivery system. 4. Drug delivery with graphene oxide-based nanocarriers. 5. Carbon nanotubes for drug delivery system. 6. Graphene quantum dots for drug delivery. 7. Fullerene-based drug delivery system. 8. Carbon-based nanocomposites for drug delivery. 9. Smart carbon-based nanocarriers for drug delivery. 10. Toxicological studies of carbon-based nanocarriers. 11. Challenges and opportunities of carbon-based nanomaterials as nanocarriers. 12. Journey of nano-drug delivery systems from lab to
    clinics: Case studies.


    Dr. Mihir Kumar Purkait is a Professor in the Department of Chemical Engineering at Indian Institute of Technology Guwahati (IITG). Presently he is Chair professor of National Jal Jeevan Mission (NJJM), Min. of Jal Shakti (Govt. of India). He is energetically involved in frontier areas of Chemical Engineering with his major research interest in the field of advanced separation processes and material science.

    Prof. Purkait has done outstanding contribution in translational and applied research. Quality and quantity of his research is reflected in terms of large number of publications, patents, technology transfer, start-ups, projects, consultancies and involvement with various national and international scientific committees. His work has remarkable relevance in societal as well as industrial sectors.

    He has more than 20 years of experience in research & academics and published more than 300 papers in different reputed international journals with h-index of 69 and 12 granted patents and made 3 technology transfer. He has authored 15 books, completed 42 sponsored projects/consultancies from various funding agencies. Prof. Purkait has supervised 22 PhD students on fundamental and applied research.

    Dr. Ankush D. Sontakke is currently pursuing his Ph.D. in the Department of Chemical Engineering from the Indian Institute of Technology, Guwahati (IITG). He received his Master’s Degree (2016) in Chemical Engineering from Sant Longowal Institute of Engineering and Technology, Longowal, Punjab and B. Tech (2013) from Jawaharlal Darda Institute of Engineering and Technology, Yavatmal, Maharashtra. He worked at Multi Organics Private Limited, Chandrapur, Maharashtra, for 1 year (2013-14). Also, he served as an Assistant Professor in the Department of Chemical Engineering at Chandigarh University, Gharuan, Mohali, Punjab, during 2016-2017. His research activities are focused on Graphene and related materials such as Graphene oxide (GO), Graphene oxide nanoscrolls (GONS), Graphene quantum dots (GQDs) and their application in drug delivery systems (DDS). He is working on the advancement in DDS using various structural, morphological and functional modifications of carbon-based nanocarriers to improve their surface characteristics, biocompatibility, toxicity toward cancer cells, loading and release behavior. He has been closely working in the area of carbon-based nanocarriers and nanohybrids for their sustainable synthesis as well as application in anticancer drug delivery and stimuli-responsive carriers for the controlled release of drugs. He is also exploring strategies for therapeutic targeting and controlled drug delivery. He has published many peer-reviewed articles in reputed international journals and published several book chapters.

    Mr. Anweshan received his B. Tech (2012) degree in Chemical Engineering and Technology from the National Institute of Technology Durgapur, West Bengal, India. After completing his B. Tech, he joined the Tinplate Company of India Limited (manufacturing sector) and continued his services there as a Senior Engineer for three years (2012-2016). He then explored the start-up ecosystem growing in India and joined the Grow Green India Foundation as a Junior Research Associate and then transferred to RD Grow Green India Pvt. Ltd., an enterprise of the foundation, as a Research Associate (2016-2018). He is currently pursuing his Ph.D. degree in Chemical Engineering from the Indian Institute of Technology Guwahati, Assam, India. His research work is dedicated to the detection of contaminants in water and wastewater using low-cost green synthesized nanoparticles and their subsequent treatment through electrocoagulation. He is working on the fabrication of metallic oxide nanomaterials via green pathways for sensing trace organic compounds and pathogens in water. Presently, he is working on synthesizing carbon-based nanohybrids focused on metal-impregnated nanohybrids and hydrogels for their applications as absorbents to remove pathogens. Further, his works involve the design of standalone electrocoagulation reactors and integrated systems for the remediation of arsenic, fluoride, and iron-infested groundwater. He has several patents and published many peer-reviewed articles in reputed international journals.