Section I: Cardiovascular Disease
Chapter 1: Current views on the burden of cardiovascular disease M. Volpe
Section II: Cardiovascular Prevention
CHAPTER 2: Strategy of interventions and targets at individual and population levels
M. Volpe
CHAPTER 3: Cardiovascular prevention in children and adolescents
S. Bellone, C Partenope
Section III: Cardiovascular Risk Factors: Assessment and Identification
CHAPTER 4: Non modifiable risk factors
4.1- Age
G. Nati
4.2- Gender
E. Lodi, M.L. Poli, M. G. Modena
4.3- Genetics
S. Rubattu
CHAPTER 5: Modifiable-Risk factors
5.1- High blood pressure
G. Nardoianni, G. Tocci
5.2- High cholesterol levels
V. Bianconi, M.R. Mannarino, M. Pirro
5.3:Smoking
C. Ferri, G. Baldini
5.4- Diabetes
S. Gugliandolo, A. Giaccari, F. Cinti
CHAPTER 6: Additional and emerging risk factors
6.1- Body Weight
C. Savoia
6.2- Low HDL-Cholesterol
M.R. Mannarino, V. Bianconi, M. Pirro
- 6.3- Hypertriglyceridemia
M. Bertolotti
- 6.4- Lipoprotein(a)
M. Pirro, M.R. Mannarino, V. Bianconi
G. Liuzzo, D. Pedicino, A. d’Aiello
- 6.6- Uric acid and gout
C. Borghi, F Piani
- 6.7- Non-adherence to therapies
E. Ettorre, G. Cecchini, G. Desideri
- 6.8- Viral Infections
A. Battistoni
- 6.9- Air pollution and climate change
A. V. Mattioli, S. Sciomer
- 6.10- Antineoplastic therapy
P. Ameri, A. Battistoni, A. Minghini, L. Piras
CHAPTER 7: Subclinical Organ Damage
D. Rizzoni
7.1- Heart
M. L. Muiesan, C. Agabiti Rosei, M. Lemoli, G. Buso
7.2- Vessels
M. Salvetti, A. Paini, G. Buso, C. Agabiti Rosei, C. De Ciuceis
7.3- Kidneys
R. Pontremoli, G Leoncini
7.4- Liver
C. Savoia
CHAPTER 8: Stratification of Cardiovascular Risk in Practice
G. Gallo
CHAPTER 9: Individual Genetic Assessment for analyzing the risk of cardiovascular diseases
G.L. Condorelli
Section IV: Cardiovascular Prevention:
CHAPTER 10: Clinical approach to cardiovascular prevention in the general practice
M. Petino
CHAPTER 11: Prevention of cardiovascular risk factors in children and adolescents
S. Bellone, C Partenope
CHAPTER 12: Non pharmacological interventions
12.1- Dietary interventions
R. Volpe
12.2- Physical activity and exercise
M. L. Poli, M.G. Modena, E. Lodi
12.3- The Practice of Sport in Cardiovascular Prevention
A. Biffi, S. Palermi, L. De Martino, F. Fernando
12.4- Quit smoking
C. Ferri, L. Ferri
CHAPTER 13: Pharmacological interventions
13.1- Antihypertensive therapies
G. Nardoianni, G. Tocci
13.2- Lipid-lowering drug therapies
S. A. Di Fusco, G. Marino, F. Colivicchi
13.3- Hypolipidemic drugs: New interventions
N. Ferri, A. Corsini
13.4- Diabetes
C. Morciano, A. Giaccari, F. Cinti
13.5- Antiplatelet drugs
C. Patrono
13.6- Antiobesity drugs
D. Pedicino, A. d’Aiello
CHAPTER 14: Secondary Prevention
C. Morisco, A. Bellis, C. Mauro, B. Trimarco
CHAPTER 15: Tertiary Prevention and Rehabilitation 327
M. Volterrani
Biography
Massimo Volpe is Emeritus Professor of Sapienza University of Rome and Professor of Cardiology Department of Clinical and Molecular Medicine, Sapienza University of Rome. He is President of the Italian Society of Cardiovascular Prevention and a member of the Scientific Committee of the Italian Society of Hypertension and is a scientific consultant at IRCCS San Raffaele in Rome. He is the former Dean of the Faculty of Medicine and Psychology and Deputy Rector for Research Planning at the University of Rome Sapienza. He has been Assistant Professor at New York Hospital-Cornell University Medical College, National Coordinator of the Research Evaluation Process for the Area of Medicine (VQR) Ministry of University and Research and a member of the National Committee for Research Supervision (CNGR). He was conferred the 2021 Peter Van Zwieten Award for Research – European Society of Hypertension.
Professor Volpe’s primary research interests are neurohormonal control of circulation and cardiovascular structural and functional abnormalities in hypertension and heart failure. He is a Fellow of the American Heart Association (High Blood Pressure Council), and European Society of Cardiology, and a Hypertension Specialist of the European Society of Hypertension. He has served as President of the Italian Society of Hypertension and of the Italian College of Cardiology.
Professor Volpe has authored more than 1000 publications in prestigious cardiovascular, peer-reviewed, international journals with an H-index of 108 and more than 106,570 citations. He has lectured in major international congresses and at leading universities worldwide and has served on the editorial boards of major cardiovascular journals.






