1st Edition

Carotid Atherosclerotic Disease Pathologic Basis for Treatment

    Carotid Atherosclerotic Disease: Pathologic Basis for Treatment reviews the natural history of carotid atherosclerotic plaque and outlines different pathologic characteristics of asymptomatic and symptomatic carotid plaque with the intent to give a pathology-based rationale for assessment, risk stratification and decision-making therapeutic strateg

    Section 1: Epidemiology. Incidence and Prevalence of Carotid Atherosclerosis. Section 2: Pathologic Basis of Carotid Atherosclerotic Disease. Carotid Atherogenesis: from Experimental Models to Human. Natural History of Carotid Atherosclerotic Plaque. Pathobiologic Determinants of Carotid Plaque Development. Anatomo-clinical Correlation Between Symptomatic Plaque and Ischemic Damage. Risk Factors and the Morphology of Atherosclerotic Carotid Plaque From Coronaries to Carotids: Shifting the Paradigm of Plaque Vulnerability. Section 3: Imaging of the Carotid Plaque. Imaging Modalities to Identify High-risk Subgroups. EcoDoppler: Diagnostic Tool or also an Impact on Indication and Treatment? Role of Angiography and IVUS 110. Optimal Utilization of Spiral-CT and MRI. Section 4: Carotid Atherosclerosis Treatment. Medical Treatment for Carotid Atherosclerosis Prevention. Two Similar Stories: From CABG to PCI and from CEA to CAS 13. Registry and Trials of CAS Vs. CEA. Should Interventional Strategy be Based on Diagnostic Imaging? Protection Devices: A Must or an Option? Acute Stroke Treatment. The Role of Surgery. Credentialing for Carotid Stenting. Section 5: Future Developments. New Diagnostic Tools to Identify Vulnerable Carotid Plaques & Targeting for Pharmacologic/gene Therapy in Carotid Atherosclerotic Disease


    Sangiorgi\, Giuseppe; Holmes\, David R.; Rosenfield\, Kenneth; Hopkins\, L. Nelson; Spagnoli\, Luigi