1st Edition

Case Reports in Cardiology Congenital Heart Disease

Edited By William C. Roberts Copyright 2024
    328 Pages 216 B/W Illustrations
    by CRC Press

    328 Pages 216 B/W Illustrations
    by CRC Press

    From the earliest days of medicine to the present, case reports have been a critical aspect of clinical education and knowledge development. In this comprehensive volume, Dr. William C. Roberts, a renowned expert in the field, explores the rich history and ongoing importance of case reports in cardiology.

    Through engaging and insightful analysis, the book demonstrates how case reports have provided physicians with crucial insights into rare diseases, complex conditions, and groundbreaking treatments. Drawing on a vast range of sources, from ancient manuscripts to cutting-edge journals, it offers a unique perspective on the role of case reports in medical education and practice of congenital heart diseases and associated cardiac complications. It underscores how case reports can be used to enhance diagnostic accuracy, identify new treatment options, and promote innovation in the field. In addition, the book provides valuable insights into the process of writing and publishing case reports, including tips for young physicians looking to break into the field.

    The book will be an indispensable guide to the history, practice, and ongoing significance of case reports for medical students, physicians, and researchers alike.

    Key features:

    • Provides a rich repository of diverse case reports in cardiology published by the editor and his colleagues over 61 years
    • Features 52 clinical case studies related to Congenital Heart Disease useful for medical students and practicing cardiologists
    • Valuable resource for young physicians seeking to establish a foothold in medical research and academics

    *Note: Cases are numbered based on their number in WCR’s CV.


    1. Braunwald E, Ross RS, Morrow AG, Roberts WC. Differential diagnosis of mitral regurgitation in childhood; Clinical pathological conference at the National Institutes of Health. Ann Intern Med. 1961;54(6):1223-1242

    3. Folse R, Roberts WC, Cornell WP. Increased bronchial collateral circulation in a patient with transposition of the great vessels and pulmonary hypertension. Am J Cardiol. 1961;8(2):282-287.

    12. Roberts WC. Anomalous origin of both coronary arteries from the pulmonary artery. Am J Cardiol. 1962;10(4):595-600.

    15. Roberts WC, Mason DT, Braunwald E. Survival to adulthood in a patient with complete transposition of the great vessels: including a note on the association of endocrine tumors with heart disease. Ann Intern Med. 1962;57(5):834-842.

    16. Roberts WC, Goldblatt A, Mason DT, Morrow AG. Combined congenital pulmonic and mitral stenosis. N Engl J Med. 1962;267(25):1298-1299.

    17. Roberts WC, Berry WB, Morrow AG. The significance of asplenia in the recognition of inoperable congenital heart disease. Circulation. 1962;26(6):1251-1253.

    18. Roberts WC, Morrow AG, Mason DT, Braunwald E. Spontaneous closure of ventricular septal defect, anatomic proof in an adult with tricuspid atresia. Circulation. 1963;27(1):90-94.

    30. Roberts WC, Morrow AG. Aortico-left ventricular tunnel. A cause of massive aortic regurgitation and of intracardiac aneurysm. Am J Med. 1965;39(4):662-667.

    51. Roberts WC, Eggleston JC, Humphries JO. Complex congenital cardiac malformation: corrected transposition, origin of both great vessels from the anatomic right ventricle, common ventricle, and dextroversion. Johns Hopkins Med J. 1967;120(3):155-161.

    79. Perloff JK, Urschell CW, Roberts WC, Caulfield WH Jr. Aneurysmal dilatation of the coronary arteries in cyanotic congenital cardiac disease. Report of a forty-year-old patient with the Taussig-Bing complex. Am J Med. 1968;45(5):802-810.

    84. Glancy DL, Braunwald NS, O’Brien KP, Roberts WC. Scimitar syndrome associated with patent ductus arteriosus, aortic coarctation and irreversible pulmonary hypertension. Johns Hopkins Med J. 1968;123(6):297-304.

    92. Roberts WC. Anomalous left ventricular band. An unemphasized cause of a precordial musical murmur. Am J Cardiol. 1969;23(5):735-738.

    93. Dean DC, Pamukcoglu T, Roberts WC. Rocks in the right ventricle. A complication of congenital right ventricular infundibular obstruction associated with chronic pulmonary parenchymal disease. Am J Cardiol. 1969;23(5):744-747.

    94. Simon AL, Friedman WF, Roberts WC. The angiographic features of a case of parachute mitral valve. Am Heart J. 1969;77(6):809-813.

    108. Liddy TJ, Roberts WC. Chronic intravascular hemolysis (renal hemosiderosis) after incomplete prosthetic closure of a ventricular septal defect and noncalcific aortic regurgitation. Am J Clin Pathol. 1970;53(6):839-842.

    122. Fortuin NJ, Roberts WC. Congenital atresia of the left main coronary artery. Am J Med. 1971;50(3):385-389.

    138. Falcone MW, Perloff JK, Roberts WC. Aneurysm of the nonpatent ductus arteriosus. Am J Cardiol. 1972;29(3):422-426.

    145. Falcone MW, Roberts WC. Atresia of the right atrial ostium of the coronary sinus unassociated with persistence of the left superior vena cava: a clinicopathologic study of four adult patients. Am Heart J. 1972;83(5):604-611.

    215. Fishbein MC, Obma R, Roberts WC. Unruptured sinus of Valsalva aneurysm. Am J Cardiol. 1975;35(6):918-922.

    327. Scott LP, Chandra RS, Roberts WC. Complex congenital heart disease: a multiplicity of therapeutic options. Am Heart J. 1978;96(6):806-810.

    332. Covarrubias EA, Sheikh MU, Isner JM, Gomes M, Hufnagel CA, Roberts WC. Calcific pulmonic stenosis in adulthood: treatment by valve replacement (porcine xenograft) with postoperative hemodynamic evaluation. Chest. 1979;75(3):399-402.

    387. Cabin HS, Lester LA, Roberts WC. Congenital heart disease with trisomy 13: use of the echocardiogram in delineating the location of a left-to-right shunt. Am Heart J. 1980;100(4):563-566.

    399. Arnett EN, Aisner SC, Lewis KB, Tecklenberg P, Brawley RK, Roberts WC. Pulmonic valve stenosis, atrial septal defect and left-to-right interatrial shunting with intact ventricular septum. A distinct hemodynamic-morphologic syndrome. Chest. 1980;78(5):759-762.

    406. Waller BF, Sheikh MU, Roberts WC. Prolapsing atrioventricular valve in partial atrioventricular defect. Am Heart J. 1981;101(1):108-110.

    435. Cabin HS, Wood TP, Smith JO, Roberts WC. Structure—function correlations in cardiovascular and pulmonary diseases (CPC): Ebstein’s anomaly in the elderly. Chest. 1981;80(2):212-214.

    460. McManus BM, Luetzeler J, Roberts WC. Total anomalous pulmonary venous connection: survival for 62 years without surgical intervention. Am Heart J. 1982;103(2):298-301.

    479. Waller BF, Smith FA, Kerwin DM, Roberts WC. Fetal rubella 27 years later. Chest. 1982;81(6):735-738.

    482. Dicicco BS, McManus BM, Waller BF, Roberts WC. Separate aortic ostium of the left anterior descending and left circumflex coronary arteries from the left aortic sinus of Valsalva (absent left main coronary artery). Am Heart J. 1982;104(1):153-154.

    490. Roberts WC, Dicicco BS, Waller BF, et al. Origin of the left main from the right coronary artery or from the right aortic sinus with intramyocardial tunneling to the left side of the heart via the ventricular septum. The case against clinical significance of myocardial bridge or coronary tunnel. Am Heart J. 1982;104(2 Pt 1):303-305.

    508. Roberts WC, Spray TL, Shemin RJ, Maron BJ. Crisscrossed atrioventricular valves and prolonged survival. Am J Cardiol. 1982;50(6):1436-1439.

    534. Saffitz JE, McIntosh CL, Roberts WC. Massive right ventricular outflow tract aneurysm after ventriculotomy for subvalvular pulmonic stenosis associated with peripheral pulmonary arterial stenoses. Am J Cardiol. 1983;51(8):1460-1462.

    598. Warnes CA, Boger JE, Roberts WC. Eisenmenger ventricular septal defect with prolonged survival. Am J Cardiol. 1984;54(3):460-462.

    599. McManus BM, Hahn PF, Smith JA, Roberts WC, Jackson JH. Eisenmenger ductus arteriosus with prolonged survival. Am J Cardiol. 1984;54(3):462-464.

    604. Warnes CA, Shugoll GI, Wallace RB, Roberts WC. Atrioventricular septal defect (primum atrial septal defect) with prolonged survival (despite severe mitral regurgitation and pulmonary hypertension) and associated cardiac calcification (mitral anulus, coronary artery and pulmonary trunk). Am J Cardiol. 1984;54(6):689-69.

    605. Ross EM, McIntosh CL, Roberts WC. "Massive" calcification of a right ventricular outflow parietal pericardial patch in tetralogy of Fallot. Am J Cardiol. 1984;54(6):691-692.

    616. Roberts WC, Robinowitz M. Anomalous origin of the left anterior descending coronary artery from the pulmonary trunk with origin of the right and left circumflex coronary arteries from the aorta. Am J Cardiol. 1984;54(10):1381-1383.

    617. Warnes CA, Maron BJ, Jones M, Roberts WC. Asymptomatic sinus of Valsalva aneurysm causing right ventricular outflow obstruction before and after rupture. Am J Cardiol. 1984;54(10):1383-1384.

    635. Barbour DJ, Roberts WC. Origin of the right from the left main coronary artery (single coronary ostium in aorta). Am J Cardiol. 1985;55(5):609.

    642. Barth CW III, Dibdin JD, Roberts WC. Mitral valve cleft without cardiac septal defect causing severe mitral regurgitation but allowing long survival. Am J Cardiol. 1985;55(9):1229-1231.

    673. Barth CW III, Bray M, Roberts WC. Sudden death in infancy associated with origin of both left main and right coronary arteries from a common ostium above the left sinus of Valsalva. Am J Cardiol. 1986;57(4):365-366.

    725. Barbour DJ, Roberts WC. Aneurysm of the pulmonary trunk unassociated with intracardiac or great vessel left-to-right shunting. Am J Cardiol. 1987;59(1):192-194.

    848. Dollar AL, Roberts WC. Retroaortic epicardial course of the left circumflex coronary artery and anteroaortic intramyocardial (ventricular septum) course of the left anterior descending coronary artery: an unusual coronary anomaly and a proposed classification based on the number of coronary ostia in the aorta. Am J Cardiol. 1989;64(12):828-829.

    897. Brabham KR, Roberts WC. Fatal intrapericardial rupture of sinus of Valsalva aneurysm. Am Heart J. 1990;120(6 Pt 1):1455-1456.

    968. Fernicola DJ, Boodhoo VR, Roberts WC. Prolonged survival (74 years) in unoperated tetralogy of Fallot with associated mitral valve prolapse. Am J Cardiol. 1993;71(5):479-483.

    983. Shirani J, Roberts WC. Coronary ostial dimple (in the posterior aortic sinus) in the absence of other coronary arterial abnormalities. Am J Cardiol. 1993;72(1):118-119.

    990. Shirani J, Zafari AM, Roberts WC. Sudden death, right ventricular infarction, and abnormal right ventricular intramural coronary arteries in isolated congenital valvular pulmonic stenosis. Am J Cardiol. 1993;72(3):368-370.

    1545. George BA, Ko JM, Lensing FD, Kuiper JJ, Roberts WC. "Repaired" tetralogy of Fallot mimicking arrhythmogenic right ventricular cardiomyopathy (another phenocopy). Am J Cardiol. 2011;108(2):326-329.

    1629. Donaldson EE, Ko JM, Gonzalez-Stawinski G, Hall SA, Roberts WC. Secondary arrhythmogenic right ventricular cardiomyopathy decades after operative repair of tetralogy of Fallot. Am J Cardiol. 2014;114(5):806-809.

    1649. Roberts CC, Roberts WC. Large patent ductus arteriosus in a 44-year-old woman leading to calcium deposition in the left atrium and mitral and aortic valves. Tex Heart Inst J. 2015;42(3):262-264.

    1686. Roberts WC, Grayburn PA, Guileyardo JM, Stoler RC. Full development of consequences of congenital pulmonic stenosis in eighty-four years. Am J Cardiol. 2017;119(8):1284-1287.

    1697. Roberts WC, Sing AC, Guileyardo JM. Combined atresia of one left-sided and one right-sided cardiac valve in a premature newborn. Proc Bayl Univ Med Cent. 2017;30(4):437-438.

    1766. Roberts WC, Siddiqui S. Huge right ventricular outflow tract aneurysm late following total repair of tetralogy of Fallot leading to orthotopic heart transplantation. Cardiovasc Pathol. 2021;52:107332.


    William C. Roberts, MD, was born in Atlanta, Georgia, on September 11, 1932. He graduated from Southern Methodist University and Emory University School of Medicine. He did his training in internal medicine at the Boston City Hospital and at The Johns Hopkins Hospital, and his training in pathology at the National Institutes of Health. From July 1964 to March 1993, he was Chief of Pathology at the National Heart, Lung, and Blood Institute, National Institutes of Health, Bethesda, Maryland. He has published more than 1,700 articles, authored or edited 31 books, and lectured in more than 2,200 cities worldwide. He has contributed information on many cardiovascular conditions. During the past 44 years, Dr. Roberts has been program director for the Williamsburg Conference on Heart Disease held every December in Williamsburg, Virginia. The American College of Cardiology Foundation has sponsored this conference for 30 years. Since March 1993, Dr. Roberts has been the executive director of the Baylor Heart and Vascular Institute at Baylor University Medical Center in Dallas, Texas. He was also the editor-in-chief of the Baylor University Medical Center Proceedings and Dean of the A. Webb Roberts Center for Continuing Medical Education at Baylor Scott & White Health. He had been the editor-in-chief of The American Journal of Cardiology since June 1982. He received many honors including the 1978 Gifted Teacher Award from The American College of Cardiology; the 1983 College Medalist Award of the American College of Chest Physicians; the Public Health Service Commendation Medal in 1979; the 1984 Richard and Hilda Rosenthal Foundation Award from the Council of Cardiology of the American Heart Association; an honorary Doctor of Science degree from Far Eastern University, Manila, Philippines in 1995; the designation of Master from The American College of Cardiology in 2004, and the Lifetime Achievement Award of The American College of Cardiology in 2016, and the Lifetime Achievement Award for D’s CEO’s Excellence in Healthcare Awards in 2021.

    Sadly, Dr. William C. Roberts passed away in June 2023 at the age of 90, just as this book series went into production.