Case Studies in Allergic Disorders is designed for undergraduate and graduate students in immunology, medical students, and resident physicians. It describes the basic cellular and molecular mechanisms involved in the pathogenesis of commonly occurring allergic diseases and introduces the rationale for targeted treatment of allergy. Replicating the successful approach of Case Studies in Immunology, the book presents mechanisms of hypersensitivity through a selection of clinical cases that reinforce and extend the basic science. The cases are largely drawn from the records of Children’s Hospital Boston. Linking the discussion of pathogenesis to actual clinical presentation establishes important connections between the bench and bedside. The book can be used as either a stand-alone text or asa companion to Janeway’s Immunobiology and The Immune System.
Table of Contents
1. Acute Systemic Anaphylaxis
2. Allergic Asthma
3. Allergic Rhinitis
4. Allergic Diseases of the Eye
5. Atopic Dermatitis
6. Contact Sensitivity to Poison Ivy
7. Transfusion Reaction
8. Drug-induced Serum Sickness
9. Immune Dysregulation, Polyendocrinopathy, Enteropathy X-linked Disease (IPEX)
10. Hereditary Angioedema
12. Food Allergy
13. Eosinophilic Esophagitis
14. Allergic Bronchopulmonary Aspergillosis
15. Hypersensitivity Pneumonitis and Occupational Lung Disease
16. Venom Hypersensitivity
17. Hypereosinophilic Syndrome
18. Churg-Strauss Syndrome
19. Aspirin-Exacerbated Respiratory Disease (AERD)
Dr. Oettgen is the Children’s Hospital Professor of Pediatric Immunology at the Harvard Medical School and Associate Chief of the Division of Immunology at Boston Children’s Hospital. He combines clinical practice with basic research on immune mechanisms in allergic diseases.
Dr. Geha is the James L. Gamble Professor of Pediatric Immunology at the Harvard Medical School and Chief of the Division of Immunology at Boston Children’s Hospital. He combines clinical practice with research on basic mechanisms of immunity and allergy.
"...Clear, concise, insightful, and useful....[Case Studies in Allergic Disorders] is a genuinely stimulating read for the immunology enthusiast." -- Yale Journal of Biology and Medicine
"The authors have succeeded in developing a volume that is useful for teaching immunologic concepts of allergic disease to undergraduate and graduate students, interns, and residents. Overall, Oettgen and Geha have done an admirable job constructing a case-based textbook that will be useful to a diverse audience." --The Quarterly Review of Biology