Preface
1. Introduction
2. Randomized Controlled Clinical Trials
3. Missing Data Handling
4. Intercurrent Events Handling
5. Longitudinal Studies
6. Real-World Evidence Studies
7. The Art of Estimation (I): M-estimation
8. The Art of Estimation (II): TMLE
9. The Art of Estimation (III): LTMLE
10. Sensitivity Analysis
11. A Roadmap for Causal Inference
12. Applications of the Roadmap
Bibliography
Index
Biography
Yixin Fang, Ph.D. is Director of Statistics and Research Fellow at AbbVie Inc. He obtained his Ph.D. in Statistics from Columbia University and is an experienced statistician and data scientist who has a history of working in both the biopharmaceutical industry and academia.
"This book can serve as a reference for experienced statisticians interested in extending their research to semiparametric efficiency theory and incorporating machine learning approaches into their causal methodology, as well as an introductory resource for graduate students in statistics, bio-statistics, or data science interested in causal inference and applications to pharmacy."
-Ashley L. Buchanan in theĀ Journal of the American Statistical Association, July 2025.






