Cells in Evolutionary Biology: Translating Genotypes into Phenotypes - Past, Present, Future, 1st Edition (Hardback) book cover

Cells in Evolutionary Biology

Translating Genotypes into Phenotypes - Past, Present, Future, 1st Edition

Edited by Brian K. Hall, Sally A. Moody

CRC Press

280 pages | 15 Color Illus. | 13 B/W Illus.

Book Content Available Open Access*
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*Open Access content has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives (CC-BY-NC-ND) license

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Hardback: 9781498787864
pub: 2018-06-12
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This book is the first in a projected series on Evolutionary Cell Biology, the intent of which is to demonstrate the essential role of cellular mechanisms in transforming the genotype into the phenotype by transforming gene activity into evolutionary change in morphology. This book —Cells in Evolutionary Biology — evaluates the evolution of cells themselves and the role cells have been viewed to play as agents of change at other levels of biological organization. Chapters explore Darwin’s use of cells in his theory of evolution and how Weismann’s theory of the separation of germ plasm from body cells brought cells to center stage in understanding how acquired changes to cells within generations are not passed on to future generations. The study of evolution through the analysis of cell lineages during embryonic development dominated evolutionary cell biology until usurped by the switch to genes as the agents of heredity in the first decades of the 20th century. Discovery that cells exchanged organelles via symbiosis led to a fundamental reevaluation of prokaryotic and eukaryotic cells and to a reorganizations of the Tree of Life. Identification of cellular signaling centers, of mechanisms responsible for cellular patterning, and of cell behavior and cellular condensations as mediating the plasticity that enables phenotypic change during evolution, provided powerful new synergies between cell biology and evolutionary theory and the basis for Evolutionary Cell Biology.

Key Selling Features:

  • Summarizes the long history of the essential role of cells in evolutionary change.
  • Demonstrates that cellular processes transform genetic change into phenotypic change in development and in evolution.
  • Documents the evidence that cells provide the missing mechanistic link between the genotype and the phenotype in evolutionary theory.
  • Illustrates the necessity of integrating cell biology into evolutionary theory.

Table of Contents

The Role of Cells and Cell Theory in Evolutionary Thought, ca. 1840–1872

Andrew Reynolds

Germ Cells and Somatic Cells in Evolutionary Biology: August Weismann’s Germ Plasm Theory

Ariane Drösher

Cell Lineages in Ontogeny and Phylogeny from 1900

Jane Maienschein

Protists and Multiple Routes to the Evolution of Multicellularity

Vidyanand Nanjundiah, Iñaki Ruiz-Trillo, and David Kirk

Symbiosis in Eukaryotic Cell Evolution: Genomic Consequences and Changing Classification

Shinichiro Maruyama and Eunsoo Kim

Cellular Control of Time, Size, and Shape in Development and Evolution

Richard A. Schneider

Cellular Basis of Evolution in Animals: An Evo-Devo Perspective

R. Craig Albertson

Dynamical Patterning Modules Link Genotypes to Morphological Phenotypes in Multicellular Evolution

Stuart A. Newman and Karl J. Niklas

About the Editors

Brian K. Hall, University Research Professor Emeritus at Dalhousie University, was trained in Australia as an experimental embryologist. His research concentrated on the differentiation of skeletal tissues, especially, how epithelial–mesenchymal signaling initiates osteogenesis and chondrogenesis through the formation of cellular condensations. These studies led him to earlier stages of development and the origin and function of skeletogenic neural crest cells. Comparative studies, using embryos from all five classes of vertebrates provided a strong evolutionary component to his research. These studies, along with analyses of the developmental basis of homology, played significant roles in the establishing of evolutionary developmental biology. He is a Fellow of the Royal Society of Canada, Foreign Fellow of the American Academy of Arts and Science, and recipient of a Killam Prize. He was one of eight individuals awarded the first Kovalevsky Medals in 2000 to recognize the most distinguished scientists of the twentieth century in comparative zoology and evolutionary embryology.

Sally A. Moody, Professor and Chair of the Department of Anatomy and Regenerative Biology at George Washington University, received her PhD in Neuroscience during which she studied motor axon guidance cues in the trigeminal system of the chick embryo. Throughout her career, she has continued her interest in understanding the mechanisms of axon guidance, studying the role of lineage factors in Xenopus, extracellular matrix proteins in chick, and genetic mutations in mouse. As a postdoctoral fellow, Sally was introduced to Xenopus embryos, which has remained a favorite. She made extensive fate maps of cleavage stage Xenopus embryos, identified maternal mRNAs that contribute to neural fate, elucidated proteomic and metabolomic changes that occur within specific lineages during cleavage, and demonstrated lineage influences on the determination of amacrine cell fate in the retina. Currently, her laboratory is studying the gene regulatory network that stabilizes neural fate downstream of neural induction, and identifying novel factors that are required for cranial sensory placode development. Dr. Moody has served on several editorial boards in the fields of neuroscience and developmental biology, on the board of directors of several societies focused on developmental processes, and edited the books: Cell Fate and Lineage Determination and Principles in Developmental Genetics.

About the Series

Evolutionary Cell Biology

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Subject Categories

BISAC Subject Codes/Headings:
NATURE / Animals / General
SCIENCE / Life Sciences / Cytology
SCIENCE / Life Sciences / Evolution
SCIENCE / Life Sciences / General