1st Edition

Chemistry and Biology of Heterocycles Volume 2

Edited By Devalina Ray, Bimal Krishna Banik Copyright 2027
440 Pages 87 Color & 292 B/W Illustrations
by CRC Press

Heterocyclic systems are defined by the integration of one or more heteroatoms within a cyclic framework and serve as the structural foundation for a vast array of natural products, clinical pharmaceuticals, and advanced functional materials. This work examines the synthetic landscape of heterocycles, prioritizing the development of robust methodologies, mechanistic insights, and late-stage... Read more

List of Contributors

Editor Bios

 

Synthesis and Bioactivity of Heterocycles:

 

Sulphur, Oxygen & Related Heterocycles:

 

Chapter 16: Recent Advances in Synthetic Strategies, Mechanistic Aspects and Biological  Insights of Furan and Thiophene Anchored Heterocycles

Ankita Garg, Pawan Deep Kaur Sani, Teesha Thakral and Aman Bhalla

 

Chapter 17: Synthesis and Biochemical Application of Benzofuran

M. Amin Mir, Syed M. Hasnain and K. Andrews   

 

Chapter 18: Recent Advances in the Chemistry and Biology of Oxepines and Azepines

Rajat Ghosh, Manisha Kundu and Shital Kumar Chattopadhyay

 

Chapter 19: Chemistry and Biology of Naturally Occurring Dibenzo-alpha-pyrones

Asanjan Brahmachari and Goutam Brahmachari

 

Chapter 20: Synthetic and Biological Aspects in Selenium Heterocyclic Compounds

Shashikant Tiwari, Sangeeta Bajpai, Monika Kamboj and Shreya Dwivedi

 

Oxygen/Sulfur/Selenium-Functionalized Heterocycles:

 

Chapter 21: Investigating the Present Synthetic Strategies and Mechanistic Perspectives of Chalcogen (Oxo and Thio) Substituted Heterocycles with Biological Applications

Ankita Garg, Pawan Deep Kaur Sani, Rajat Dhiman and Aman Bhalla

 

Chapter 22: Synthetic Approaches to Selenium Containing/ Substituted Heterocyclic Compounds and Their Biological Relevance

Asha Rathee, Km Anjali, Ayush Islam, Devalina Ray, Sudeep Bose

 

Methods for Synthesis and Bioevaluation:

 

Chapter 23: An Update on Macrocyclization via Cross Coupling Strategy

Dripta De Joarder, Rajarshi Sarkar and Dilip K. Maiti

 

Chapter 24: Multistep Flow-Assisted Synthesis of N-Heterocyclic APIs: A Perception Of Modern Drug Discovery

Prakash K. Mandal, Md Tanjul Hoque, Rajesh Nandi, Antara Roy and Dilip K. Maiti

 

Chapter 25: Recent Advances in NHC Mediated Organocatalysis to Achieve Bioactive Heterocycles

Rajendra N. Mitra, Tanmoy Ghosh, Debabrata Barman, Satinath Sarkar and Dilip K. Maiti

 

Chapter 26: Chemistry, Synthesis and Uses of Deoxy Sugar Esters

Varsha Tiwari, Abhishek Tiwari, Bimal K. Banik

Chapter 27: Design and Therapeutic Potential of Heterocyclic Prodrugs

Km. Anjali, Suman Majee, Yashasvei Ahluwalia, Suman Mazumdar, Bimal K. Banik, Devalina Ray

 

Chapter 28: Quantitative Structure-Activity Relationships of Taxol and Related Compounds

Aparna Das and Bimal Krishna Banik

 

Index

Biography

Dr. Devalina Ray is an Assistant professor in Amity University, Noida, UP, India since October 2017. She has received her Ph.D from IIT Kharagpur, India in 2008. Thereafter, she pursued her postdoctoral research in University of Texas Medical Branch, Texas followed by University of Nebraska Medical Centre, Nebraska, USA. She joined Myongji University, Yongin as Research Professor and further continued her postdoctoral research in Hanyang University, Seoul, South Korea. She was employed as Research associate at IIT-Delhi and then continued to work there as Young Scientist till October 2017. Her research area included synthetic organic chemistry focused on transition metal-catalyzed and transition metal free C-H functionalization and cycloadditions, medicinal and natural product chemistry, green chemistry, peptide chemistry etc. The current area of interest deals with transition metal-free greener synthetic approaches to various coupling reactions and C-H functionalization. Dr. Ray is the recipient of “B. N. Mankad award from Indian Chemical Society, India. She is an affiliate member of Royal Chemical Society, CRSI, and editorial board member of American Journal of Heterocyclic Chemistry, Heterocyclic Letters and Asian J. Organic & Medicinal Chemistry. Recently, she has been recruited as the Executive Guest Editor of the journal Current Organocatalysis.

Professor Bimal K. Banik is a Professor of Prince Mohammad Bin Fahd University, Kingdom of Saudi Arabia. He was the Vice President of Research and Education Development of Community Health Systems of South Texas, a Tenured Full Professor and First President’s Endowed Professor at the University of Texas-Pan American Center for many years. Professor Banik was awarded Bachelor of Science Honors Degree in Chemistry from Itachuna Bejoy Narayan College and Master of Science Degree in Chemistry from Burdwan University. He obtained his Ph. D. degree based upon his thesis work performed at the Indian Association for the Cultivation of Science, Jadavpur, Calcutta. Dr. Banik was a Postdoctoral Fellow at Case Western Reserve University (Ohio) and Stevens Institute of Technology (New Jersey). He is a Fellow (FRSC) and Chartered Chemist (CChem) of the Royal Society of Chemistry and a Fellow of the Indian Chemical Society. Dr. Banik has been involved in organic and medicinal chemistry and biomedical research for many years. As Principal Investigator, he has been awarded $7.25 million USD grants from US National Institutes of Health, US National Cancer Institute, and US Kleberg Foundation. Professor Banik has 370 peer-reviewed publications along with 465 presentation abstracts. The number of citations of his publications is approximately 6400. He serves as a reviewer of 93, editorial board member of 28, editor-in-chief of 12, founder of 4, associate editor of 4 and guest editor of 6 journals.