Chronic Lung Disease in Early Infancy: 1st Edition (Hardback) book cover

Chronic Lung Disease in Early Infancy

1st Edition

Edited by Richard D. Bland, Jacqueline J. Coalson

CRC Press

1,096 pages

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Hardback: 9780824798710
pub: 1999-09-21
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This definitive volume presents the clinical and pathological features of bronchopulmonary dysplasia, a disease that accounts for the majority of long-term hospitalizations, slow growth, and recurrent early childhood respiratory ailments that are common in low-birth-weight newborns.

Highlights relevant animal models for studying the process of chronic lung disease through its evolution and during recovery!

Written by nearly 75 leading international authorities on lung disease during early childhood development who describe the clinical, radiographic, and pathological changes that have occurred in the 30 years since bronchopulmonary dysplasia was first discovered, Chronic Lung Disease in Early Infancy

  • focuses on the development of technology, notably changes in the application of assisted ventilation

  • traces the evolution and impact of new therapies, including prenatal glucocorticoids and postnatal surfactants

  • suggests effective therapeutic and preventive strategies

  • explains how the lungs develop structurally and functionally

  • explores how lung development is altered by injury and the repair process

  • critically examines research in the field of pediatric lung pathology

  • reviews what is known and emphasizes what needs to be learned about bronchopulmonary dysplasia

  • provides direction for future research into chronic lung disease

  • and more!
  • Reviews


    …describes the clinical, radiographic, and pathologic changes that have occurred since the discovery of bronchopulmonary dysplasia 30 years ago….highlights include…animal models that can be used to study the process of chronic lung disease through its evolution and during recovery.

    "-Pulmonary Reviews

    …an extensive and detailed review of bronchopulmonary dysplasia.

    -Doody's Health Sciences Book Reviews

    "…clearly written….

    …an extremely valuable source of information for anyone who has an interest in the biology of lung….

    …should be available in the library of any hospital.

    "-Respiratory Care

    "…valuable and well organized….

    ..should be an essential book for any chemist working in the area of solid state electrochemistry.

    "-Journal of Solid State Electrochemistry

    Table of Contents

    Clinical Aspects

    Historical Perspective: Early Observations and Subsequent Evolution of Bronchopulmonary Dysplasia

    William H. Northway, Jr.

    Epidemiology of Bronchopulmonary Dysplasia: Clinical Risk Factors and Associated Clinical Conditions

    Alma Martinez, Peter Dargaville, and H. William Taeusch

    Clinical Course and Lung Function Abnormalities During Development of Neonatal Chronic Lung Disease

    Eduardo Bancalari and Alvaro Gonzalez

    Radiographic Features of BPD and Potential Application of New Imaging Techniques

    David K. Edwards and William H. Northway, Jr.

    Pathology of Chronic Lung Disease of Early Infancy

    Jacqueline J. Coalson

    The Usefulness of Bronchoalveolar Lavage in Infants with Evolving Chronic Lung Disease

    Carl W. White and Leland L. Fan

    Inflammatory Mediators in Neonatal Lung Disease

    Christian P. Speer and Peter Groneck

    Infection in the Pathogenesis of Bronchopulmonary Dysplasia

    William E. Benitz and Ann M. Arvin

    Ventilation Strategies and Bronchopulmonary Dysplasia

    W. Alan Hodson

    Effect of Respiratory Care Practices on the Development of Bronchopulmonary Dysplasia

    Michael R. Gomes and Thomas N. Hansen

    Influence of Surfactant Replacement on Development of Bronchopulmonary Dysplasia

    Alan H. Jobe

    Drug Treatment for Established BPD

    Thomas A. Hazinski

    Nutritional Issues in Chronic Lung Disease of Premature Infants

    Ilene R. S. Sosenko, Michael T. Kinter, and Robert J. Roberts

    Pulmonary Function in BPD and Its Aftermath

    Eric C. Eichenwald

    Cardiovascular Abnormalities in Bronchopulmonary Dysplasia

    Michael Apkon, Rodrigo Nehgme, and George Lister

    Long-Term Recovery from Bronchopulmonary Dysplasia

    Solomon Alkrinawi and Victor Chernick

    The Goal: Prevention of BPD

    Mildred T. Stahlman

    Normal and Abnormal Alveolar and Airway Development

    Unique Features of the Immature Lung that Make It Vulnerable to Injury

    Scott H. Randell and Stephen L. Young

    Hormonal Effects on Lung Maturation and Disease

    Philip L. Ballard and Roberta A. Ballard

    Mechanisms and Physiological Sequelae of Reactive Species Injury to the Alveolar Epithelium

    Imad Y. Haddad, Sha Zhu, Samuel J. Tilden, and Sadid Matalon

    Surfactant in Chronic Lung Injury

    Richard J. King and Samuel Hagwood

    The Regulation of the Formation of Pulmonary Alveoli

    Donald J. Massaro and Gloria D. Massaro

    Factors Mediating Cell Growth in Lung Injury

    A. Keith Tanswell, Shilpa Buch, Mingyao Liu, and Martin Post

    Developmental Airway Structure and Function in Health and Chronic Lung Injury

    Howard B. Panitch and Thomas H. Shaffer

    Normal and Abnormal Development of the Lung Circulation and Interstitium

    Lung Development and the Effects of Chronic Hypoxia

    Sheila G. Haworth

    Altered Development of the Pulmonary Circulation in Chronic Lung Injury

    Marlene Rabinovitch

    Pulmonary Hypertension in Chronic Lung Disease of Infancy: Pathogenesis, Pathophysiology, and Treatment

    Steven H. Abman

    Connective Tissues in Lung Development and Diseases in Early Infancy

    David J. Riley

    Pulmonary Edema After Premature Birth: Progression from Acute to Chronic Lung Disease

    Richard D. Bland and David P. Carlton

    Mechanisms of Lung Injury and Repair During Development

    Molecular Mechanisms of Oxygen-Induced Lung Injury

    Charles Vincent Smith and Stephen E. Welty

    Assessment of Tissue Injury from Reactive Oxygen Metabolites

    Michael J. Thomas, Timothy W. Robison, and Henry Jay Forman

    Chronic Lung Disease of Early Infancy: Role of Neutrophils

    Diane E. Lorant, Kurt Albertine, and John F. Bohnsack

    The Role of Pulmonary Macrophages in Chronic Lung Disease of Early Infancy

    Michael P. Sherman and William E. Truog

    Oxidants and Antioxidants: What Role Do They Play in Chronic Lung Disease

    H. Lee Frank and Ilene R. S. Sosenko

    Proteolytic Enzymes and Their Inhibitor in Lung Health and Disease

    John R. Hoidal and Mari K. Hoidal

    Site and Mechanism-Directed Interventions for Tissue Free Radical Injury

    William R. Berrington, Margaret M. Tarpey, Bruce A. Freeman, and Bruce R. Pitt

    Models of Lung Injury and Repair During Development

    Genetic Models for the Study of Autocrine-Paracrine Signaling in Lung Development and Repair

    Jeffrey A. Whitsett and Thomas R. Korfhagen

    Animal Models of Chronic Lung Injury

    Jacqueline J. Coalson, Steven R. Seidner, and Robert A. De Lemos

    Subject Categories

    BISAC Subject Codes/Headings:
    MEDICAL / General
    MEDICAL / Infectious Diseases
    MEDICAL / Pediatrics
    MEDICAL / Pulmonary & Thoracic Medicine